In a model of immunoglobulin heavy-chain (IGH)/MYC translocation, the Igh 3' regulatory region induces MYC expression at the immature stage of B cell development.
about
Long-range oncogenic activation of Igh-c-myc translocations by the Igh 3' regulatory region.Comparison of identical and functional Igh alleles reveals a nonessential role for Eμ in somatic hypermutation and class-switch recombinationRole of the Igh intronic enhancer Eμ in clonal selection at the pre-B to immature B cell transition.Mechanisms and impacts of chromosomal translocations in cancers.Complex oncogenic translocations with gene amplification are initiated by specific DNA breaks in lymphocytes.
P2860
In a model of immunoglobulin heavy-chain (IGH)/MYC translocation, the Igh 3' regulatory region induces MYC expression at the immature stage of B cell development.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on October 2007
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
In a model of immunoglobulin h ...... e stage of B cell development.
@en
In a model of immunoglobulin h ...... e stage of B cell development.
@nl
type
label
In a model of immunoglobulin h ...... e stage of B cell development.
@en
In a model of immunoglobulin h ...... e stage of B cell development.
@nl
prefLabel
In a model of immunoglobulin h ...... e stage of B cell development.
@en
In a model of immunoglobulin h ...... e stage of B cell development.
@nl
P2093
P2860
P356
P1476
In a model of immunoglobulin h ...... e stage of B cell development.
@en
P2093
Laurel A Eckhardt
Siegfried Janz
Sung Sup Park
P2860
P304
P356
10.1002/GCC.20480
P577
2007-10-01T00:00:00Z