Generation of mutant mice by pronuclear injection of circular plasmid expressing Cas9 and single guided RNA.
about
CRISPR-Cas9: A Revolutionary Tool for Cancer ModellingAdvantages of using the CRISPR/Cas9 system of genome editing to investigate male reproductive mechanisms using mouse modelsCRISPR/Cas9 mediated genome editing in ES cells and its application for chimeric analysis in miceCRISPR/Cas9-Mediated Rapid Generation of Multiple Mouse Lines Identified Ccdc63 as Essential for SpermiogenesisCpf1 nucleases demonstrate robust activity to induce DNA modification by exploiting homology directed repair pathways in mammalian cells.CRISPR/Cas9-mediated genome editing in wild-derived mice: generation of tamed wild-derived strains by mutation of the a (nonagouti) gene.Next-generation mammalian genetics toward organism-level systems biologyRapid generation of mouse models with defined point mutations by the CRISPR/Cas9 system.Highly efficient targeted mutagenesis in one-cell mouse embryos mediated by the TALEN and CRISPR/Cas systems.A single blastocyst assay optimized for detecting CRISPR/Cas9 system-induced indel mutations in miceCRISPR/Cas9-mediated gene knockout in the mouse brain using in utero electroporationConditional targeting of Ispd using paired Cas9 nickase and a single DNA template in mice.Somatic mosaicism and allele complexity induced by CRISPR/Cas9 RNA injections in mouse zygotes.A mouse geneticist's practical guide to CRISPR applications.2015 Guidelines for Establishing Genetically Modified Rat Models for Cardiovascular Research.Mutations in GANAB, Encoding the Glucosidase IIα Subunit, Cause Autosomal-Dominant Polycystic Kidney and Liver DiseaseDetailed phenotypic and molecular analyses of genetically modified mice generated by CRISPR-Cas9-mediated editingSingle-step generation of rabbits carrying a targeted allele of the tyrosinase gene using CRISPR/Cas9.Large genomic fragment deletions and insertions in mouse using CRISPR/Cas9.Production of knockout mice by DNA microinjection of various CRISPR/Cas9 vectors into freeze-thawed fertilized oocytesEfficient Multiple Genome Modifications Induced by the crRNAs, tracrRNA and Cas9 Protein Complex in Zebrafish.CRISPR/Cas9-mediated reporter knock-in in mouse haploid embryonic stem cells.Generation of mutant mice via the CRISPR/Cas9 system using FokI-dCas9Electroporation enables the efficient mRNA delivery into the mouse zygotes and facilitates CRISPR/Cas9-based genome editing.Double strand break repair by capture of retrotransposon sequences and reverse-transcribed spliced mRNA sequences in mouse zygotesMouse Genome Editing Using the CRISPR/Cas System.Gtsf1l and Gtsf2 Are Specifically Expressed in Gonocytes and Spermatids but Are Not Essential for Spermatogenesis.Peri-implantation lethality in mice carrying megabase-scale deletion on 5qc3.3 is caused by Exoc1 null mutationGeneration of VDR Knock-Out Mice via Zygote Injection of CRISPR/Cas9 System.Loss of maternal ANNEXIN A10 via a 34-kb deleted-type copy number variation is associated with embryonic mortality in Japanese Black cattleΔ40p53α suppresses tumor cell proliferation and induces cellular senescence in hepatocellular carcinoma cellsSplitAx: A novel method to assess the function of engineered nucleases.Finding of a highly efficient ZFN pair for Aqpep gene functioning in murine zygotesMouse genome engineering via CRISPR-Cas9 for study of immune function.A non-inheritable maternal Cas9-based multiple-gene editing system in miceNon-canonical NF-κB signalling and ETS1/2 cooperatively drive C250T mutant TERT promoter activation.Hepatocyte Factor JMJD5 Regulates Hepatitis B Virus Replication through Interaction with HBxGPI-AP release in cellular, developmental, and reproductive biology.Targeted mutagenesis in chicken using CRISPR/Cas9 system.Highly Efficient CRISPR/Cas9-Mediated Cloning and Functional Characterization of Gastric Cancer-Derived Epstein-Barr Virus Strains.
P2860
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P2860
Generation of mutant mice by pronuclear injection of circular plasmid expressing Cas9 and single guided RNA.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年学术文章
@wuu
2013年学术文章
@zh-cn
2013年学术文章
@zh-hans
2013年学术文章
@zh-my
2013年学术文章
@zh-sg
2013年學術文章
@yue
2013年學術文章
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2013年學術文章
@zh-hant
name
Generation of mutant mice by p ...... ng Cas9 and single guided RNA.
@en
Generation of mutant mice by p ...... ng Cas9 and single guided RNA.
@nl
type
label
Generation of mutant mice by p ...... ng Cas9 and single guided RNA.
@en
Generation of mutant mice by p ...... ng Cas9 and single guided RNA.
@nl
prefLabel
Generation of mutant mice by p ...... ng Cas9 and single guided RNA.
@en
Generation of mutant mice by p ...... ng Cas9 and single guided RNA.
@nl
P2860
P50
P356
P1433
P1476
Generation of mutant mice by p ...... ing Cas9 and single guided RNA
@en
P2093
Ayako Isotani
Haruhiko Miyata
P2860
P2888
P356
10.1038/SREP03355
P407
P577
2013-11-27T00:00:00Z