Amphotericin B selection of mutant Chinese hamster cells with defects in the receptor-mediated endocytosis of low density lipoprotein and cholesterol biosynthesis
about
LDLC encodes a brefeldin A-sensitive, peripheral Golgi protein required for normal Golgi functionMurine SR-BI, a high density lipoprotein receptor that mediates selective lipid uptake, is N-glycosylated and fatty acylated and colocalizes with plasma membrane caveolaeA novel casein kinase 2 alpha-subunit regulates membrane protein traffic in the human hepatoma cell line HuH-7.Identification of a pharmaceutical compound that partially corrects the Niemann-Pick C phenotype in cultured cells.Use of a mutant cell line to study the kinetics and function of O-linked glycosylation of low density lipoprotein receptorsElimination or rescue of cells in culture by specifically targeted liposomes containing methotrexate or formyl-tetrahydrofolate.Three types of low density lipoprotein receptor-deficient mutant have pleiotropic defects in the synthesis of N-linked, O-linked, and lipid-linked carbohydrate chains.Unusual forms of low density lipoprotein receptors in hamster cell mutants with defects in the receptor structural geneDisruptions in Golgi structure and membrane traffic in a conditional lethal mammalian cell mutant are corrected by epsilon-COP.Loss of transcriptional activation of three sterol-regulated genes in mutant hamster cells.Isolation and characterization of an extragenic suppressor of the low-density lipoprotein receptor-deficient phenotype of a Chinese hamster ovary cell mutantCharacterization of a family of gamma-ray-induced CHO mutants demonstrates that the ldlA locus is diploid and encodes the low-density lipoprotein receptorReceptor-mediated endocytosis of low density lipoprotein: somatic cell mutants define multiple genes required for expression of surface-receptor activity.Human hepatoma cell mutant defective in cell surface protein trafficking.
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P2860
Amphotericin B selection of mutant Chinese hamster cells with defects in the receptor-mediated endocytosis of low density lipoprotein and cholesterol biosynthesis
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on September 1983
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Amphotericin B selection of mu ...... n and cholesterol biosynthesis
@en
Amphotericin B selection of mu ...... and cholesterol biosynthesis.
@nl
type
label
Amphotericin B selection of mu ...... n and cholesterol biosynthesis
@en
Amphotericin B selection of mu ...... and cholesterol biosynthesis.
@nl
prefLabel
Amphotericin B selection of mu ...... n and cholesterol biosynthesis
@en
Amphotericin B selection of mu ...... and cholesterol biosynthesis.
@nl
P2093
P2860
P356
P1476
Amphotericin B selection of mu ...... n and cholesterol biosynthesis
@en
P2093
P2860
P304
P356
10.1073/PNAS.80.18.5607
P407
P577
1983-09-01T00:00:00Z