Hyperproinsulinemia is associated with increased beta cell demand after hemipancreatectomy in humans
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Lessons learned from more than 1,000 pancreas transplants at a single institutionRecovery of endocrine function after islet and pancreas transplantation{beta}-Cell secretory capacity and demand in recipients of islet, pancreas, and kidney transplantsDual and opposing roles of the unfolded protein response regulated by IRE1alpha and XBP1 in proinsulin processing and insulin secretion.Elevated Intact Proinsulin Levels During an Oral Glucose Challenge Indicate Progressive ß-Cell Dysfunction and May Be Predictive for Development of Type 2 Diabetes.Effect of glucagon-like peptide-1 on beta- and alpha-cell function in isolated islet and whole pancreas transplant recipientsShort- and long-term outcome for living pancreas donors.Metabolic Stress and Compromised Identity of Pancreatic Beta Cells.Review of approved pioglitazone combinations for type 2 diabetes.Development of diabetes mellitus in living pancreas donors and recipients.Islet transplantation: factors in short-term islet survival.Exposure of human islets to cytokines can result in disproportionately elevated proinsulin release.Risk of glucose intolerance and diabetes in hemipancreatectomized donors selected for normal preoperative glucose metabolism.Overnight inhibition of insulin secretion restores pulsatility and proinsulin/insulin ratio in type 2 diabetes.Role of reduced β-cell mass versus impaired β-cell function in the pathogenesis of type 2 diabetes.Middle segment pancreatectomy: a useful tool in the management of pancreatic neoplasms.Disproportionate hyperproinsulinemia, beta-cell restricted prohormone convertase 2 deficiency, and cell cycle inhibitors expression by human islets transplanted into athymic nude mice: insights into nonimmune-mediated mechanisms of delayed islet graEffects of mitiglinide, a short-acting insulin secretagogue, on daily glycemic variability and oxidative stress markers in Japanese patients with type 2 diabetes mellitus.Reduced postprandial proinsulinaemia and 32-33 split proinsulinaemia after a mixed meal in type 2 diabetic patients following sensitization to insulin with pioglitazone.Misfolded proinsulin in the endoplasmic reticulum during development of beta cell failure in diabetes.Proinsulin/C-peptide ratio, glucagon and remission in new-onset Type 1 diabetes mellitus in young adults.
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P2860
Hyperproinsulinemia is associated with increased beta cell demand after hemipancreatectomy in humans
description
article científic
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article scientifique
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articolo scientifico
@it
artigo científico
@pt
bilimsel makale
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scientific article published on January 1996
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Hyperproinsulinemia is associa ...... r hemipancreatectomy in humans
@en
Hyperproinsulinemia is associa ...... hemipancreatectomy in humans.
@nl
type
label
Hyperproinsulinemia is associa ...... r hemipancreatectomy in humans
@en
Hyperproinsulinemia is associa ...... hemipancreatectomy in humans.
@nl
prefLabel
Hyperproinsulinemia is associa ...... r hemipancreatectomy in humans
@en
Hyperproinsulinemia is associa ...... hemipancreatectomy in humans.
@nl
P2093
P2860
P356
P1476
Hyperproinsulinemia is associa ...... r hemipancreatectomy in humans
@en
P2093
P2860
P304
P356
10.1172/JCI118435
P407
P577
1996-01-01T00:00:00Z