Transient oxidative stress damages mitochondrial machinery inducing persistent beta-cell dysfunction.
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Interventions to preserve beta-cell function in the management and prevention of type 2 diabetesPhysiological effects and therapeutic potential of proinsulin C-peptideZinc and zinc transporter regulation in pancreatic islets and the potential role of zinc in islet transplantationStress-induced dissociations between intracellular calcium signaling and insulin secretion in pancreatic isletsHeterozygous SOD2 deletion impairs glucose-stimulated insulin secretion, but not insulin action, in high-fat-fed mice.Resveratrol potentiates glucose-stimulated insulin secretion in INS-1E beta-cells and human islets through a SIRT1-dependent mechanism.Glucose metabolism determines resistance of cancer cells to bioenergetic crisis after cytochrome-c release.Changes in mitochondrial carriers exhibit stress-specific signatures in INS-1Eβ-cells exposed to glucose versus fatty acids.Preservation of cellular glutathione status and mitochondrial membrane potential by N-acetylcysteine and insulin sensitizers prevent carbonyl stress-induced human brain endothelial cell apoptosis.In-Utero Low-Dose Irradiation Leads to Persistent Alterations in the Mouse Heart ProteomeMitochondrial hormesis in pancreatic β cells: does uncoupling protein 2 play a role?Robust glyoxalase activity of Hsp31, a ThiJ/DJ-1/PfpI family member protein, is critical for oxidative stress resistance in Saccharomyces cerevisiae.NADPH oxidase NOX2 defines a new antagonistic role for reactive oxygen species and cAMP/PKA in the regulation of insulin secretion.Oxidative stress in diabetes: implications for vascular and other complications.U-Shaped Association between Plasma Manganese Levels and Type 2 DiabetesReactive aldehydes--second messengers of free radicals in diabetes mellitus.Intracellular and extracellular adenosine triphosphate in regulation of insulin secretion from pancreatic β cells (β).Redox control of enzymatic functions: The electronics of life's circuitry.Therapeutic concentrations of antidepressants inhibit pancreatic beta-cell function via mitochondrial complex inhibition.C-peptide antioxidant adaptive pathways in β cells and diabetes.Diabetogenic milieus induce specific changes in mitochondrial transcriptome and differentiation of human pancreatic islets.Inhibitor of differentiation proteins protect against oxidative stress by regulating the antioxidant-mitochondrial response in mouse beta cells.Autocrine C-peptide mechanism underlying INS1 beta cell adaptation to oxidative stress.Oxidative metabolism genes are not responsive to oxidative stress in rodent Beta cell linesGelam Honey Attenuates the Oxidative Stress-Induced Inflammatory Pathways in Pancreatic Hamster Cells.ROS accumulation and IGF-IR inhibition contribute to fenofibrate/PPARalpha -mediated inhibition of glioma cell motility in vitro.Upregulation of UCP2 in beta-cells confers partial protection against both oxidative stress and glucotoxicity.Signaling of reactive oxygen and nitrogen species in Diabetes mellitus.Mitochondrial oxidative stress contributes differently to rat pancreatic islet cell apoptosis and insulin secretory defects after prolonged culture in a low non-stimulating glucose concentration.Effect of gelam honey on the oxidative stress-induced signaling pathways in pancreatic hamster cells.Effect of the Zinc Oxide Nanoparticles and Thiamine for the Management of Diabetes in Alloxan-Induced Mice: a Stereological and Biochemical Study.Hepatocyte Nuclear Factor-1β Controls Mitochondrial Respiration in Renal Tubular Cells.Mitochondrial protein S-nitrosation protects against ischemia reperfusion-induced denervation at neuromuscular junction in skeletal muscle.Epicatechin potentiation of glucose-stimulated insulin secretion in INS-1 cells is not dependent on its antioxidant activity.The effects of oral carvacrol treatment against H2O2 induced injury on isolated pancreas islet cells of rats.Mitochondrial DNA oxidative damage contributes to cardiomyocyte ischemia/reperfusion-injury in rats: cardioprotective role of lycopene.Redox-Dependent Inflammation in Islet Transplantation Rejection.
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P2860
Transient oxidative stress damages mitochondrial machinery inducing persistent beta-cell dysfunction.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on 22 June 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Transient oxidative stress dam ...... sistent beta-cell dysfunction.
@en
Transient oxidative stress dam ...... sistent beta-cell dysfunction.
@nl
type
label
Transient oxidative stress dam ...... sistent beta-cell dysfunction.
@en
Transient oxidative stress dam ...... sistent beta-cell dysfunction.
@nl
prefLabel
Transient oxidative stress dam ...... sistent beta-cell dysfunction.
@en
Transient oxidative stress dam ...... sistent beta-cell dysfunction.
@nl
P2093
P2860
P356
P1476
Transient oxidative stress dam ...... sistent beta-cell dysfunction.
@en
P2093
Daniel A Cunha
Decio L Eizirik
Thierry Brun
P2860
P304
23602-23612
P356
10.1074/JBC.M109.024323
P407
P577
2009-06-22T00:00:00Z