Vaccinia virus K1L and C7L inhibit antiviral activities induced by type I interferons.
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Structure Function Studies of Vaccinia Virus Host Range Protein K1 Reveal a Novel Functional Surface for Ankyrin Repeat ProteinsPotent Neutralization of Vaccinia Virus by Divergent Murine Antibodies Targeting a Common Site of Vulnerability in L1 ProteinPoxviral ankyrin proteinsModulation of NF-κB signalling by microbial pathogensImproved NYVAC-based vaccine vectorsM062 is a host range factor essential for myxoma virus pathogenesis and functions as an antagonist of host SAMD9 in human cellsInsertion of vaccinia virus C7L host range gene into NYVAC-B genome potentiates immune responses against HIV-1 antigensEffective control of viral infections by the adaptive immune system requires assistance from innate immunity.Enhancement of vaccinia virus based oncolysis with histone deacetylase inhibitors.C7L family of poxvirus host range genes inhibits antiviral activities induced by type I interferons and interferon regulatory factor 1.Attenuation of vaccinia Tian Tan strain by removal of viral TC7L-TK2L and TA35R genes.Redundancy complicates the definition of essential genes for vaccinia virus.Glycosaminoglycans mediate retention of the poxvirus type I interferon binding protein at the cell surface to locally block interferon antiviral responses.Deletion of major nonessential genomic regions in the vaccinia virus Lister strain enhances attenuation without altering vaccine efficacy in mice.Molecular genetic analysis of orf virus: a poxvirus that has adapted to skinComparative analysis of poxvirus orthologues of the vaccinia virus E3 protein: modulation of protein kinase R activity, cytokine responses, and virus pathogenicityMutational analysis of vaccinia virus E3 protein: the biological functions do not correlate with its biochemical capacity to bind double-stranded RNAIdentification of Restriction Factors by Human Genome-Wide RNA Interference Screening of Viral Host Range Mutants Exemplified by Discovery of SAMD9 and WDR6 as Inhibitors of the Vaccinia Virus K1L-C7L- Mutant.In vitro inhibition of monkeypox virus production and spread by Interferon-β.Structural basis for antagonizing a host restriction factor by C7 family of poxvirus host-range proteins.The poxvirus C7L host range factor superfamily.Attenuation of monkeypox virus by deletion of genomic regionsThe N-terminus of vaccinia virus host range protein C7L is essential for function.Myxoma virus M064 is a novel member of the poxvirus C7L superfamily of host range factors that controls the kinetics of myxomatosis in European rabbits.Vaccinia virus encodes a novel inhibitor of apoptosis that associates with the apoptosome.Deletion of the K1L Gene Results in a Vaccinia Virus That Is Less Pathogenic Due to Muted Innate Immune Responses, yet Still Elicits Protective Immunity.SAMD9 is an innate antiviral host factor with stress response properties that can be antagonized by poxviruses.Sequence and phylogenetic analysis of host-range (E3L, K3L, and C7L) and structural protein (B5R) genes of buffalopox virus isolates from buffalo, cattle, and human in India.A paralogous pair of mammalian host restriction factors form a critical host barrier against poxvirus infection.Modulating Vaccinia Virus Immunomodulators to Improve Immunological Memory.
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P2860
Vaccinia virus K1L and C7L inhibit antiviral activities induced by type I interferons.
description
article científic
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article scientifique
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articolo scientifico
@it
artigo científico
@pt
bilimsel makale
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scientific article published on 05 August 2009
@en
vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Vaccinia virus K1L and C7L inhibit antiviral activities induced by type I interferons.
@en
Vaccinia virus K1L and C7L inhibit antiviral activities induced by type I interferons.
@nl
type
label
Vaccinia virus K1L and C7L inhibit antiviral activities induced by type I interferons.
@en
Vaccinia virus K1L and C7L inhibit antiviral activities induced by type I interferons.
@nl
prefLabel
Vaccinia virus K1L and C7L inhibit antiviral activities induced by type I interferons.
@en
Vaccinia virus K1L and C7L inhibit antiviral activities induced by type I interferons.
@nl
P2093
P2860
P356
P1433
P1476
Vaccinia virus K1L and C7L inhibit antiviral activities induced by type I interferons.
@en
P2093
Canhua Jiang
Janilyn Arsenio
Jingxin Cao
Kevin Dick
Xiangzhi Meng
P2860
P304
10627-10636
P356
10.1128/JVI.01260-09
P407
P577
2009-08-05T00:00:00Z