Matrix metalloproteinase 12 overexpression in lung epithelial cells plays a key role in emphysema to lung bronchioalveolar adenocarcinoma transition.
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Influence of Immune Myeloid Cells on the Extracellular Matrix During Cancer MetastasisSugar-Based Arylsulfonamide Carboxylates as Selective and Water-Soluble Matrix Metalloproteinase-12 InhibitorsSynthesis and in Vitro and in Vivo Evaluation of MMP-12 Selective Optical ProbesAre healthy smokers really healthy?ATXN1 protein family and CIC regulate extracellular matrix remodeling and lung alveolarizationApi6/AIM/Spα/CD5L overexpression in alveolar type II epithelial cells induces spontaneous lung adenocarcinomaSTAT3 knockdown reduces pancreatic cancer cell invasiveness and matrix metalloproteinase-7 expression in nude mice.Stat3 downstream gene product chitinase 3-like 1 is a potential biomarker of inflammation-induced lung cancer in multiple mouse lung tumor models and humans.Global gene expression profile progression in Gaucher disease mouse modelsCritical roles of lysosomal acid lipase in myelopoiesis.Myeloid-derived suppressor cells are involved in lysosomal acid lipase deficiency-induced endothelial cell dysfunctions.Validation of a blood protein signature for non-small cell lung cancerA comparative study of matrix remodeling in chronic models for COPD; mechanistic insights into the role of TNF-α.Macrophage metalloelastase (MMP-12) deficiency mitigates retinal inflammation and pathological angiogenesis in ischemic retinopathy.Interleukin 6, but not T helper 2 cytokines, promotes lung carcinogenesis.Overexpression of dominant negative peroxisome proliferator-activated receptor-γ (PPARγ) in alveolar type II epithelial cells causes inflammation and T-cell suppression in the lung.Matrix metalloproteinase 12 overexpression in myeloid lineage cells plays a key role in modulating myelopoiesis, immune suppression, and lung tumorigenesis.FRET-based and other fluorescent proteinase probes.Myeloid-specific expression of human lysosomal acid lipase corrects malformation and malfunction of myeloid-derived suppressor cells in lal-/- miceSignal transducer and activator of transcription 3 (Stat3C) promotes myeloid-derived suppressor cell expansion and immune suppression during lung tumorigenesis.Inhibition of PPARγ in myeloid-lineage cells induces systemic inflammation, immunosuppression, and tumorigenesis.Myeloid-specific Fos-related antigen-1 regulates cigarette smoke-induced lung inflammation, not emphysema, in miceExperimental Pneumocystis lung infection promotes M2a alveolar macrophage-derived MMP12 productionDifferential transcriptomic analysis of spontaneous lung tumors in B6C3F1 mice: comparison to human non-small cell lung cancer.Critical role of PPARγ in myeloid-derived suppressor cell-stimulated cancer cell proliferation and metastasis.Fibrotic response of tissue remodeling in COPD.Negative regulation of myeloid-derived suppressor cells in cancer.Chronic exposure to particles caused bronchioloalveolar carcinoma in a patient with cryptogenic organizing pneumonia evaluated by elemental analysis.Senolytic drugs target alveolar epithelial cell function and attenuate experimental lung fibrosis ex vivo.Hepatocyte-Specific Expression of Human Lysosome Acid Lipase Corrects Liver Inflammation and Tumor Metastasis in lal(-/-) Mice.Knockdown of MMP12 inhibits the growth and invasion of lung adenocarcinoma cells.MMP-12, a Promising Therapeutic Target for Neurological Diseases.Matrix metalloproteinases: their functional role in lung cancer.Lung Epithelial Cell-Specific Expression of Human Lysosomal Acid Lipase Ameliorates Lung Inflammation and Tumor Metastasis in Lipa(-/-) MiceLung inflammatory effects, tumorigenesis, and emphysema development in a long-term inhalation study with cigarette mainstream smoke in mice.Effects of short-term cigarette smoke exposure on Fischer 344 rats and on selected lung proteins.[Research progress of matrix metalloproteinase 12 in non-small cell lung cancer].Expression and network analysis of YBX1 interactors for identification of new drug targets in lung adenocarcinoma.Deregulated Stat3 signaling dissociates pulmonary inflammation from emphysema in gp130 mutant mice
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Matrix metalloproteinase 12 overexpression in lung epithelial cells plays a key role in emphysema to lung bronchioalveolar adenocarcinoma transition.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on 25 August 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Matrix metalloproteinase 12 ov ...... lar adenocarcinoma transition.
@en
Matrix metalloproteinase 12 ov ...... lar adenocarcinoma transition.
@nl
type
label
Matrix metalloproteinase 12 ov ...... lar adenocarcinoma transition.
@en
Matrix metalloproteinase 12 ov ...... lar adenocarcinoma transition.
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prefLabel
Matrix metalloproteinase 12 ov ...... lar adenocarcinoma transition.
@en
Matrix metalloproteinase 12 ov ...... lar adenocarcinoma transition.
@nl
P2093
P2860
P1433
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Matrix metalloproteinase 12 ov ...... lar adenocarcinoma transition.
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P2093
P2860
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10.1158/0008-5472.CAN-09-0577
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P577
2009-08-25T00:00:00Z