Lupus-specific antibodies reveal an altered pattern of somatic mutation
about
Perturbations in the impact of mutational activity on Vlambda genes in systemic lupus erythematosusImmunoglobulin heavy chain variable region gene replacement As a mechanism for receptor revision in rheumatoid arthritis synovial tissue B lymphocytesB cells in autoimmune diseases: insights from analyses of immunoglobulin variable (Ig V) gene usage.The rise and fall of long-lived humoral immunity: terminal differentiation of plasma cells in health and disease.Immunoglobulin variable-region gene usage in systemic autoimmune diseases.The effect of anti-CD40 ligand antibody on B cells in human systemic lupus erythematosus.Receptor revision and systemic lupus.Activation-induced deaminase-deficient MRL/lpr mice secrete high levels of protective antibodies against lupus nephritis.Initial clinical trial of epratuzumab (humanized anti-CD22 antibody) for immunotherapy of systemic lupus erythematosusSurrogate light chain expressing human peripheral B cells produce self-reactive antibodies.Vaccination with minigenes encoding V(H)-derived major histocompatibility complex class I-binding epitopes activates cytotoxic T cells that ablate autoantibody-producing B cells and inhibit lupus.Defective B cell tolerance checkpoints in systemic lupus erythematosusA genetic lesion that arrests plasma cell homing to the bone marrow.Autoreactive IgG memory antibodies in patients with systemic lupus erythematosus arise from nonreactive and polyreactive precursors.Mucosal immunology of HIV infection.Immunoglobulin kappa chain receptor editing in systemic lupus erythematosus.Role of Structure-Based Changes due to Somatic Mutation in Highly Homologous DNA-Binding and DNA-Hydrolyzing Autoantibodies Exemplified by A23P Substitution in the VH Domain.Time between onset of apoptosis and release of nucleosomes from apoptotic cells: putative implications for systemic lupus erythematosus.Mathematical analysis of antigen selection in somatically mutated immunoglobulin genes associated with autoimmunity.Expression of Y7 cross-reactive idiotope on human IgM molecules.
P2860
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P2860
Lupus-specific antibodies reveal an altered pattern of somatic mutation
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年学术文章
@wuu
1997年学术文章
@zh-cn
1997年学术文章
@zh-hans
1997年学术文章
@zh-my
1997年学术文章
@zh-sg
1997年學術文章
@yue
1997年學術文章
@zh
1997年學術文章
@zh-hant
name
Lupus-specific antibodies reveal an altered pattern of somatic mutation
@en
Lupus-specific antibodies reveal an altered pattern of somatic mutation.
@nl
type
label
Lupus-specific antibodies reveal an altered pattern of somatic mutation
@en
Lupus-specific antibodies reveal an altered pattern of somatic mutation.
@nl
prefLabel
Lupus-specific antibodies reveal an altered pattern of somatic mutation
@en
Lupus-specific antibodies reveal an altered pattern of somatic mutation.
@nl
P2093
P2860
P356
P1476
Lupus-specific antibodies reveal an altered pattern of somatic mutation
@en
P2093
A J Manheimer-Lory
P2860
P304
P356
10.1172/JCI119796
P407
P577
1997-11-01T00:00:00Z