Adenoviral delivery of E2F-1 directs cell cycle reentry and p53-independent apoptosis in postmitotic adult myocardium in vivo.
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Role of cardiac stem cells in cardiac pathophysiology: a paradigm shift in human myocardial biologyOrigin of cardiomyocytes in the adult heartInhibition of E2F abrogates the development of cardiac myocyte hypertrophyForced expression of the cyclin B1-CDC2 complex induces proliferation in adult rat cardiomyocytesEnhanced proliferation of monolayer cultures of embryonic stem (ES) cell-derived cardiomyocytes following acute loss of retinoblastoma.The retinoblastoma tumor-suppressor gene, the exception that proves the ruleDevelopmental defects and tumor predisposition in Rb mutant mice.Induction of transformation and p53-dependent apoptosis by adenovirus type 5 E4orf6/7 cDNA.The oxygen-rich postnatal environment induces cardiomyocyte cell-cycle arrest through DNA damage responseRestrictions in cell cycle progression of adult vestibular supporting cells in response to ectopic cyclin D1 expression.BNIP3 subfamily BH3-only proteins: mitochondrial stress sensors in normal and pathological functions.Cardiac progenitor cells and bone marrow-derived very small embryonic-like stem cells for cardiac repair after myocardial infarction.Cardiac muscle regeneration: lessons from development.Strategies for cardiac regeneration and repair.Adenovirus E2F1 overexpression sensitizes LNCaP and PC3 prostate tumor cells to radiation in vivo.The role of E2F1 in the development of hypertrophic cardiomyopathyCell senescence and hypermitogenic arrest.Targeting the cell cycle machinery for the treatment of cardiovascular disease.Cardiac regeneration based on mechanisms of cardiomyocyte proliferation and differentiationInhibition of p53 function prevents renin-angiotensin system activation and stretch-mediated myocyte apoptosisCDK9 and its repressor LARP7 modulate cardiomyocyte proliferation and response to injury in the zebrafish heartIntense myocyte formation from cardiac stem cells in human cardiac hypertrophy.Mechanisms of myocardial regeneration.MEF2D deficiency in neonatal cardiomyocytes triggers cell cycle re-entry and programmed cell death in vitro.Cardiac stem cells and mechanisms of myocardial regeneration.Sequestration of p27 within the cytoplasm of cardiac myocytes in chronic ischemic heart disease: pathogenic implications for ischemic cardiomyopathyCardiac myocyte cell cycle control in development, disease, and regeneration.Acute myocardial infarction induced functional cardiomyocytes to re-enter the cell cycleNotch activates cell cycle reentry and progression in quiescent cardiomyocytes.Muscle ring finger 1 and muscle ring finger 2 are necessary but functionally redundant during developmental cardiac growth and regulate E2F1-mediated gene expression in vivo.Cardiac stem cells and progenitors: developmental biology and therapeutic challenges.Innate regeneration in the aging heart: healing from within.Harnessing the power of dividing cardiomyocytes.Signaling Pathways in Cardiac Myocyte Apoptosis.Evolving approaches to heart regeneration by therapeutic stimulation of resident cardiomyocyte cell cycle.The role of E2F-1 and downstream target genes in mediating ischemia/reperfusion injury in vivo.Akt promotes survival of cardiomyocytes in vitro and protects against ischemia-reperfusion injury in mouse heart.Differential regulation of cardiomyocyte survival and hypertrophy by MDM2, an E3 ubiquitin ligase.Loss of Adult Cardiac Myocyte GSK-3 Leads to Mitotic Catastrophe Resulting in Fatal Dilated Cardiomyopathy.Mdm2 inhibition of p53 induces E2F1 transactivation via p21.
P2860
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P2860
Adenoviral delivery of E2F-1 directs cell cycle reentry and p53-independent apoptosis in postmitotic adult myocardium in vivo.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on December 1997
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Adenoviral delivery of E2F-1 d ...... otic adult myocardium in vivo.
@en
Adenoviral delivery of E2F-1 d ...... otic adult myocardium in vivo.
@nl
type
label
Adenoviral delivery of E2F-1 d ...... otic adult myocardium in vivo.
@en
Adenoviral delivery of E2F-1 d ...... otic adult myocardium in vivo.
@nl
prefLabel
Adenoviral delivery of E2F-1 d ...... otic adult myocardium in vivo.
@en
Adenoviral delivery of E2F-1 d ...... otic adult myocardium in vivo.
@nl
P2093
P2860
P356
P1476
Adenoviral delivery of E2F-1 d ...... otic adult myocardium in vivo.
@en
P2093
L A Kirshenbaum
L D Truong
L H Michael
M Abdellatif
M D Schneider
S Chakraborty
P2860
P304
P356
10.1172/JCI119817
P407
P577
1997-12-01T00:00:00Z