Dynamics of the late Na(+) current during cardiac action potential and its contribution to afterdepolarizations.
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Na+ channel function, regulation, structure, trafficking and sequestrationA computational modelling approach combined with cellular electrophysiology data provides insights into the therapeutic benefit of targeting the late Na+ current.Cardiac Na Channels: Structure to FunctionEffects of Wenxin Keli on Cardiac Hypertrophy and Arrhythmia via Regulation of the Calcium/Calmodulin Dependent Kinase II Signaling Pathway.Synchronous systolic subcellular Ca2+-elevations underlie ventricular arrhythmia in drug-induced long QT type 2.Power-Law Dynamics of Membrane Conductances Increase Spiking Diversity in a Hodgkin-Huxley Model.KN-93 inhibits IKr in mammalian cardiomyocytes.The link between abnormal calcium handling and electrical instability in acquired long QT syndrome--Does calcium precipitate arrhythmic storms?Deranged sodium to sudden death.The late sodium current in heart failure: pathophysiology and clinical relevance.The Significance of the Late Na+ Current for Arrhythmia Induction and the Therapeutic Antiarrhythmic Potential of Ranolazine.Murine Electrophysiological Models of Cardiac Arrhythmogenesis.Multiple targets for flecainide action: implications for cardiac arrhythmogenesis.Role of abnormal repolarization in the mechanism of cardiac arrhythmia.Cytosolic calcium changes affect the incidence of early afterdepolarizations in canine ventricular myocytes.Electrophysiological Determination of Submembrane Na(+) Concentration in Cardiac Myocytes.Dynamics of sodium current mediated early afterdepolarizationsContribution of the late sodium current to intracellular sodium and calcium overload in rabbit ventricular myocytes treated by anemone toxin.A model of cardiac ryanodine receptor gating predicts experimental Ca2+-dynamics and Ca2+-triggered arrhythmia in the long QT syndrome.Contribution of ion currents to beat-to-beat variability of action potential duration in canine ventricular myocytes.Late sodium current associated cardiac electrophysiological and mechanical dysfunction.Beat-to-beat variability of cardiac action potential duration: underlying mechanism and clinical implications.
P2860
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P2860
Dynamics of the late Na(+) current during cardiac action potential and its contribution to afterdepolarizations.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 06 September 2013
@en
vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Dynamics of the late Na
@nl
Dynamics of the late Na(+) cur ...... ution to afterdepolarizations.
@en
type
label
Dynamics of the late Na
@nl
Dynamics of the late Na(+) cur ...... ution to afterdepolarizations.
@en
prefLabel
Dynamics of the late Na
@nl
Dynamics of the late Na(+) cur ...... ution to afterdepolarizations.
@en
P2093
P2860
P1476
Dynamics of the late Na(+) cur ...... ution to afterdepolarizations.
@en
P2093
Balazs Horvath
Leighton T Izu
Peter P Nanasi
Tamas Banyasz
Ye Chen-Izu
Zhong Jian
P2860
P356
10.1016/J.YJMCC.2013.08.010
P577
2013-09-06T00:00:00Z