Ranolazine decreases diastolic calcium accumulation caused by ATX-II or ischemia in rat hearts.
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Ranolazine: A Contemporary ReviewThe role of late I Na in development of cardiac arrhythmiasNew treatment options for late Na current, arrhythmias, and diastolic dysfunctionLate sodium current contributes to diastolic cell Ca2+ accumulation in chronic heart failure.Cardiac contractile dysfunction during acute hyperglycemia due to impairment of SERCA by polyol pathway-mediated oxidative stress.Ranolazine: a new approach to treating an old problem.Complex excitation dynamics underlie polymorphic ventricular tachycardia in a transgenic rabbit model of long QT syndrome type 1Mechanism of action of the new anti-ischemia drug ranolazine.Ranolazine inhibits NaV1.5-mediated breast cancer cell invasiveness and lung colonizationEffect of ranolazine on left ventricular dyssynchrony in patients with coronary artery disease.Antagonism of Nav channels and α1-adrenergic receptors contributes to vascular smooth muscle effects of ranolazine.Late sodium current in failing heart: friend or foe?Utility of ranolazine in chronic stable angina patients.Inhibition of late sodium current to reduce electrical and mechanical dysfunction of ischaemic myocardium.The cardiac persistent sodium current: an appealing therapeutic target?Ranolazine combined with enalapril or metoprolol prevents progressive LV dysfunction and remodeling in dogs with moderate heart failure.Diastolic transient inward current in long QT syndrome type 3 is caused by Ca2+ overload and inhibited by ranolazineThe arrhythmogenic consequences of increasing late INa in the cardiomyocyte.Dynamics of the late Na(+) current during cardiac action potential and its contribution to afterdepolarizations.Taking diabetes to heart--deregulation of myocardial lipid metabolism in diabetic cardiomyopathy.Ranolazine: an anti-anginal drug with further therapeutic potential.Ranolazine: an antianginal drug with antiarrhythmic properties.Late sodium current inhibition in acquired and inherited ventricular (dys)function and arrhythmias.Ranolazine: a review of its use as add-on therapy in patients with chronic stable angina pectoris.Ranolazine: clinical applications and therapeutic basis.New antiarrhythmic targets to control intracellular calcium handling.The late sodium current in heart failure: pathophysiology and clinical relevance.The Significance of the Late Na+ Current for Arrhythmia Induction and the Therapeutic Antiarrhythmic Potential of Ranolazine.Na+ dysregulation coupled with Ca2+ entry through NCX1 promotes muscular dystrophy in mice.Therapeutic inhibition of fatty acid oxidation in right ventricular hypertrophy: exploiting Randle's cycle.Late INa increases diastolic SR-Ca2+-leak in atrial myocardium by activating PKA and CaMKII.Ranolazine decreases mechanosensitivity of the voltage-gated sodium ion channel Na(v)1.5: a novel mechanism of drug action.Nav1.5-dependent persistent Na+ influx activates CaMKII in rat ventricular myocytes and N1325S mice.Ranolazine as an adjunct to cardioplegia: a potential new therapeutic application.The antianginal agent, ranolazine, reduces myocardial infarct size but does not alter anatomic no-reflow or regional myocardial blood flow in ischemia/reperfusion in the rabbit.An increase of late sodium current induces delayed afterdepolarizations and sustained triggered activity in atrial myocytes.Inhibition of late Na+ current, a novel target to improve diastolic function and electrical abnormalities in Dahl salt-sensitive rats.Relaxation and the Role of Calcium in Isolated Contracting Myocardium From Patients With Hypertensive Heart Disease and Heart Failure With Preserved Ejection Fraction.Late sodium current associated cardiac electrophysiological and mechanical dysfunction.
P2860
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P2860
Ranolazine decreases diastolic calcium accumulation caused by ATX-II or ischemia in rat hearts.
description
2006 nî lūn-bûn
@nan
2006 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Ranolazine decreases diastolic ...... -II or ischemia in rat hearts.
@ast
Ranolazine decreases diastolic ...... -II or ischemia in rat hearts.
@en
Ranolazine decreases diastolic ...... -II or ischemia in rat hearts.
@nl
type
label
Ranolazine decreases diastolic ...... -II or ischemia in rat hearts.
@ast
Ranolazine decreases diastolic ...... -II or ischemia in rat hearts.
@en
Ranolazine decreases diastolic ...... -II or ischemia in rat hearts.
@nl
prefLabel
Ranolazine decreases diastolic ...... -II or ischemia in rat hearts.
@ast
Ranolazine decreases diastolic ...... -II or ischemia in rat hearts.
@en
Ranolazine decreases diastolic ...... -II or ischemia in rat hearts.
@nl
P2093
P1476
Ranolazine decreases diastolic ...... X-II or ischemia in rat hearts
@en
P2093
Alexander S Clanachan
Heather Fraser
Jeffrey J McVeigh
Luiz Belardinelli
Peter E Light
P304
P356
10.1016/J.YJMCC.2006.08.012
P50
P577
2006-10-05T00:00:00Z