Synthesis and HDAC inhibitory activity of isosteric thiazoline-oxazole largazole analogs. - Wikidata - awgldk - TriplyDB

Synthesis and HDAC inhibitory activity of isosteric thiazoline-oxazole largazole analogs.

Synthesis and HDAC inhibitory activity of isosteric thiazoline-oxazole largazole analogs.

http://www.wikidata.org/entity/Q37383739

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Exploration of Novel Inhibitors for Class I Histone Deacetylase Isoforms by QSAR Modeling and Molecular Dynamics Simulation Assays Synthesis and biological evaluation of largazole analogues with modified surface recognition cap groups Comparative pharmacokinetic properties and antitumor activity of the marine HDACi Largazole and Largazole peptide isostere Variable active site loop conformations accommodate the binding of macrocyclic largazole analogues to HDAC8 Modular synthesis and biological activity of pyridyl-based analogs of the potent Class I Histone Deacetylase Inhibitor Largazole.Synthesis and biological evaluation of largazole zinc-binding group analogs.Natural and Synthetic Macrocyclic Inhibitors of the Histone Deacetylase Enzymes.Largazole Analogues as Histone Deacetylase Inhibitors and Anticancer Agents: An Overview of Structure-Activity Relationships.

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Synthesis and HDAC inhibitory activity of isosteric thiazoline-oxazole largazole analogs.

http://www.wikidata.org/entity/Q37383739

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article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on 18 June 2013

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vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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name

Synthesis and HDAC inhibitory activity of isosteric thiazoline-oxazole largazole analogs.

@en

Synthesis and HDAC inhibitory activity of isosteric thiazoline-oxazole largazole analogs.

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type

label

Synthesis and HDAC inhibitory activity of isosteric thiazoline-oxazole largazole analogs.

@en

Synthesis and HDAC inhibitory activity of isosteric thiazoline-oxazole largazole analogs.

@nl

prefLabel

Synthesis and HDAC inhibitory activity of isosteric thiazoline-oxazole largazole analogs.

@en

Synthesis and HDAC inhibitory activity of isosteric thiazoline-oxazole largazole analogs.

@nl

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J.BMCL.2013.06.012

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Bioorganic & Medicinal Chemistry Letters

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Synthesis and HDAC inhibitory activity of isosteric thiazoline-oxazole largazole analogs.

@en

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Albert A Bowers

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Guillermina Estiu

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James E Bradner

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Jennifer M Guerra-Bubb

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Olaf Wiest

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Robert M Williams

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Ronald Paranal

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William B Smith

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The role of HDAC6 in cancer

Synthesis and conformation-activity relationships of the peptide isosteres of FK228 and largazole.

Total synthesis and biological mode of action of largazole: a potent class I histone deacetylase inhibitor.

On the inhibition of histone deacetylase 8

Synthesis and histone deacetylase inhibitory activity of largazole analogs: alteration of the zinc-binding domain and macrocyclic scaffold

Discovery, biological activity, synthesis and potential therapeutic utility of naturally occurring histone deacetylase inhibitors.

Structure and activity of largazole, a potent antiproliferative agent from the Floridian marine cyanobacterium Symploca sp.

Inhibitors of human histone deacetylase: synthesis and enzyme and cellular activity of straight chain hydroxamates.

Total synthesis and molecular target of largazole, a histone deacetylase inhibitor.

Structural origin of selectivity in class II-selective histone deacetylase inhibitors.

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6025-6028

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scholarly article

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10.1016/J.BMCL.2013.06.012

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21

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23

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2013-06-18T00:00:00Z

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24035339

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3859309

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