Farnesyltransferase haplodeficiency reduces neuropathology and rescues cognitive function in a mouse model of Alzheimer disease.

Farnesyltransferase haplodeficiency reduces neuropathology and rescues cognitive function in a mouse model of Alzheimer disease.

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http://www.wikidata.org/entity/Q37388833
Protein prenylation and synaptic plasticity: implications for Alzheimer's diseaseTriptolide preserves cognitive function and reduces neuropathology in a mouse model of Alzheimer's diseaseInhibiting geranylgeranylation increases neurite branching and differentially activates cofilin in cell bodies and growth conesSimvastatin treatment enhances NMDAR-mediated synaptic transmission by upregulating the surface distribution of the GluN2B subunit.Human Cortical Neural Stem Cells Expressing Insulin-Like Growth Factor-I: A Novel Cellular Therapy for Alzheimer's Disease.Impaired geranylgeranyltransferase-I regulation reduces membrane-associated Rho protein levels in aged mouse brain.The Role of Geranylgeranyltransferase I-Mediated Protein Prenylation in the Brain.Exploring the biochemistry of the prenylome and its role in disease through proteomics: progress and potential.Haplodeficiency of Cathepsin D does not affect cerebral amyloidosis and autophagy in APP/PS1 transgenic mice.Systemic or Forebrain Neuron-Specific Deficiency of Geranylgeranyltransferase-1 Impairs Synaptic Plasticity and Reduces Dendritic Spine Density.Isoprenoids and protein prenylation: implications in the pathogenesis and therapeutic intervention of Alzheimer's disease.
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Farnesyltransferase haplodeficiency reduces neuropathology and rescues cognitive function in a mouse model of Alzheimer disease.

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http://www.wikidata.org/entity/Q37388833
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 17 October 2013
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Farnesyltransferase haplodefic ...... se model of Alzheimer disease.
@en
Farnesyltransferase haplodefic ...... se model of Alzheimer disease.
@nl
type
label
Farnesyltransferase haplodefic ...... se model of Alzheimer disease.
@en
Farnesyltransferase haplodefic ...... se model of Alzheimer disease.
@nl
prefLabel
Farnesyltransferase haplodefic ...... se model of Alzheimer disease.
@en
Farnesyltransferase haplodefic ...... se model of Alzheimer disease.
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P698
P921
P932
P356
P1433
P1476
Farnesyltransferase haplodefic ...... se model of Alzheimer disease.
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P698
P921
P932