The peroxisome proliferator-activated receptor gamma agonist pioglitazone improves cardiometabolic risk and renal inflammation in murine lupus. - Wikidata - awgldk - TriplyDB

The peroxisome proliferator-activated receptor gamma agonist pioglitazone improves cardiometabolic risk and renal inflammation in murine lupus.

The peroxisome proliferator-activated receptor gamma agonist pioglitazone improves cardiometabolic risk and renal inflammation in murine lupus.

http://www.wikidata.org/entity/Q37395321

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Cardiovascular disease in lupus: insights and updates Type I interferons promote fatal immunopathology by regulating inflammatory monocytes and neutrophils during Candida infections An essential role of caspase 1 in the induction of murine lupus and its associated vascular damage The peroxisome-proliferator activated receptor-γ agonist pioglitazone modulates aberrant T cell responses in systemic lupus erythematosus.Peroxisome proliferator-activated receptor gamma negatively regulates IFN-beta production in Toll-like receptor (TLR) 3- and TLR4-stimulated macrophages by preventing interferon regulatory factor 3 binding to the IFN-beta promoter.Pioglitazone restores phagocyte mitochondrial oxidants and bactericidal capacity in chronic granulomatous disease.Engraftment of peripheral blood mononuclear cells from systemic lupus erythematosus and antiphospholipid syndrome patient donors into BALB-RAG-2-/- IL-2Rγ-/- mice: a promising model for studying human disease.The PPAR-γ antagonist GW9662 elicits differentiation of M2c-like cells and upregulation of the MerTK/Gas6 axis: a key role for PPAR-γ in human macrophage polarization Cross-species transcriptional network analysis defines shared inflammatory responses in murine and human lupus nephritis Type I interferons modulate vascular function, repair, thrombosis, and plaque progression in murine models of lupus and atherosclerosis Nephropathy in Pparg-null mice highlights PPARγ systemic activities in metabolism and in the immune system.Epidermal injury promotes nephritis flare in lupus-prone mice.Peptidylarginine deiminase inhibition is immunomodulatory and vasculoprotective in murine lupus Anti-inflammatory Agents: Present and Future Milk fat globule-EGF factor 8 suppresses the aberrant immune response of systemic lupus erythematosus-derived neutrophils and associated tissue damage.Cardiovascular risk in rheumatoid arthritis and systemic autoimmune rheumatic disorders: a suggested model of preventive strategy.Why are kids with lupus at an increased risk of cardiovascular disease?Update on cardiovascular disease in lupus.Immunometabolism in systemic lupus erythematosus.Metabolic abnormalities and oxidative stress in lupus.PPARγ expression is increased in systemic lupus erythematosus patients and represses CD40/CD40L signaling pathway.Endothelial cell peroxisome proliferator-activated receptor γ reduces endotoxemic pulmonary inflammation and injury.Pioglitazone improves the cardiovascular profile in patients with uncomplicated systemic lupus erythematosus: a double-blind randomized clinical trial.

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The peroxisome proliferator-activated receptor gamma agonist pioglitazone improves cardiometabolic risk and renal inflammation in murine lupus.

http://www.wikidata.org/entity/Q37395321

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articolo scientifico

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bilimsel makale

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scientific article published on 20 July 2009

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vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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name

The peroxisome proliferator-ac ...... inflammation in murine lupus.

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The peroxisome proliferator-ac ...... inflammation in murine lupus.

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The peroxisome proliferator-ac ...... inflammation in murine lupus.

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The peroxisome proliferator-ac ...... inflammation in murine lupus.

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The peroxisome proliferator-ac ...... inflammation in murine lupus.

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The peroxisome proliferator-ac ...... inflammation in murine lupus.

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JIMMUNOL.0804341

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Journal of Immunology

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The peroxisome proliferator-ac ...... l inflammation in murine lupus

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Ann Randolph

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Frank C Brosius

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Hongyu Zhang

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James L Park

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Jeffrey B Hodgin

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Jeffrey H Wang

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Mariana J Kaplan

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Matthias Kretzler

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Seth G Thacker

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Subramaniam Pennathur

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P2860

The mechanisms of action of PPARs

Circulating endothelial progenitor cells and cardiovascular outcomes

Troglitazone inhibits vascular smooth muscle cell growth and intimal hyperplasia

The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity

The peroxisome proliferator-activated receptor gamma agonist rosiglitazone ameliorates murine lupus by induction of adiponectin

Inflammation, atherosclerosis, and coronary artery disease

PPAR-gamma agonists inhibit production of monocyte inflammatory cytokines

The peroxisome proliferator-activated receptor-gamma is a negative regulator of macrophage activation

Short-term treatment with rosiglitazone improves glucose tolerance, insulin sensitivity and endothelial function in renal transplant recipients.

Peroxisome proliferator-activated receptors in the cardiovascular system.

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10.4049/JIMMUNOL.0804341

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