Frequent truncating mutations of STAG2 in bladder cancer.
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Sequencing Overview of Ewing Sarcoma: A Journey across Genomic, Epigenomic and Transcriptomic LandscapesSMC complexes link gene expression and genome architectureControversies and challenges in research on urogenital schistosomiasis-associated bladder cancerCohesin mutations in myeloid malignancies: underlying mechanismsComplete loss of STAG2 expression is an indicator of good prognosis in patients with bladder cancer.Patient Mutation Directed shRNA Screen Uncovers Novel Bladder Tumor Growth Suppressors.Defective sister chromatid cohesion is synthetically lethal with impaired APC/C function.Whole-genome sequencing of bladder cancers reveals somatic CDKN1A mutations and clinicopathological associations with mutation burden.Association between Polymorphisms in MicroRNAs and Risk of Urological Cancer: A Meta-Analysis Based on 17,019 Subjects.The genomic landscape of the Ewing Sarcoma family of tumors reveals recurrent STAG2 mutation.Glioblastoma cells containing mutations in the cohesin component STAG2 are sensitive to PARP inhibitionA randomized phase 2 trial of gemcitabine/cisplatin with or without cetuximab in patients with advanced urothelial carcinoma.Genetic alterations of the cohesin complex genes in myeloid malignancies.Cohesin gene mutations in tumorigenesis: from discovery to clinical significanceConcurrent alterations in TERT, KDM6A, and the BRCA pathway in bladder cancer.Enhancer alterations in cancer: a source for a cell identity crisis.Structure and function of cohesin's Scc3/SA regulatory subunitPan-cancer network analysis identifies combinations of rare somatic mutations across pathways and protein complexesWhole-exome sequencing of muscle-invasive bladder cancer identifies recurrent mutations of UNC5C and prognostic importance of DNA repair gene mutations on survival.Genomic predictors of survival in patients with high-grade urothelial carcinoma of the bladder.Molecular biology of bladder cancer.The UBC-40 Urothelial Bladder Cancer cell line index: a genomic resource for functional studies.Intact Cohesion, Anaphase, and Chromosome Segregation in Human Cells Harboring Tumor-Derived Mutations in STAG2.GON4L Drives Cancer Growth through a YY1-Androgen Receptor-CD24 Axis.Cohesin loss alters adult hematopoietic stem cell homeostasis, leading to myeloproliferative neoplasmsLeukemia-Associated Cohesin Mutants Dominantly Enforce Stem Cell Programs and Impair Human Hematopoietic Progenitor Differentiation.Differential clonal evolution in oesophageal cancers in response to neo-adjuvant chemotherapyThe three-dimensional cancer genome.Loss of cohesin complex components STAG2 or STAG3 confers resistance to BRAF inhibition in melanoma.STAG2 is a clinically relevant tumor suppressor in pancreatic ductal adenocarcinoma.New treatments for bladder cancer: when will we make progress?Cohesin in cancer: chromosome segregation and beyond.Functional interplay between cohesin and Smc5/6 complexes.Molecular biology of bladder cancer: new insights into pathogenesis and clinical diversity.The role of genomics in the management of advanced bladder cancer.Chromosome Dynamics during Mitosis.Targeting Signaling Transduction Pathways in Bladder Cancer.Toward personalized management in bladder cancer: the promise of novel molecular taxonomy.BAF180 promotes cohesion and prevents genome instability and aneuploidy.The role of mutations in the cohesin complex in acute myeloid leukemia.
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Frequent truncating mutations of STAG2 in bladder cancer.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 13 October 2013
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Frequent truncating mutations of STAG2 in bladder cancer.
@en
Frequent truncating mutations of STAG2 in bladder cancer.
@nl
type
label
Frequent truncating mutations of STAG2 in bladder cancer.
@en
Frequent truncating mutations of STAG2 in bladder cancer.
@nl
prefLabel
Frequent truncating mutations of STAG2 in bladder cancer.
@en
Frequent truncating mutations of STAG2 in bladder cancer.
@nl
P2093
P2860
P356
P1433
P1476
Frequent truncating mutations of STAG2 in bladder cancer.
@en
P2093
Abdel G Elkahloun
Arlene Siefker-Radtke
Björn Volkmer
Bogdan Czerniak
Brian D Robinson
C David James
Dan Theodorescu
David A Solomon
Dazhong Zhuang
George Netto
P2860
P2888
P304
P356
10.1038/NG.2800
P407
P577
2013-10-13T00:00:00Z