Variations in the neuropathology of familial Alzheimer's disease.
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Autosomal Dominant Alzheimer Disease: A Unique Resource to Study CSF Biomarker Changes in Preclinical ADInconsistencies and controversies surrounding the amyloid hypothesis of Alzheimer's diseaseDefining the earliest pathological changes of Alzheimer's diseaseThree dimensions of the amyloid hypothesis: time, space and 'wingmen'Origins of Alzheimer's disease: reconciling cerebrospinal fluid biomarker and neuropathology data regarding the temporal sequence of amyloid-beta and tau involvement.Familial dementia with frontotemporal features associated with M146V presenilin-1 mutationPresenilin/gamma-Secretase and Inflammation.Anti-aβ therapeutics in Alzheimer's disease: the need for a paradigm shiftThe Arctic AβPP mutation leads to Alzheimer's disease pathology with highly variable topographic deposition of differentially truncated AβFunctional connectivity in autosomal dominant and late-onset Alzheimer disease.Large quantities of Abeta peptide are constitutively released during amyloid precursor protein metabolism in vivo and in vitro.Immunotherapy targeting pathological tau prevents cognitive decline in a new tangle mouse modelEvolution of the diagnostic criteria for degenerative and cognitive disorders.Neuroinflammatory Cytokines-The Common Thread in Alzheimer's PathogenesisAge-related neurodegeneration and memory loss in down syndrome.Genetic Disorders with Tau Pathology: A Review of the Literature and Report of Two Patients with Tauopathy and Positive Family Histories.Distinct patterns of APP processing in the CNS in autosomal-dominant and sporadic Alzheimer diseaseBACE1 and presenilin/γ-secretase regulate proteolytic processing of KCNE1 and 2, auxiliary subunits of voltage-gated potassium channels.Similarities between familial and sporadic autopsy-proven progressive supranuclear palsy.Genetic influences on atrophy patterns in familial Alzheimer's disease: a comparison of APP and PSEN1 mutations.The pattern of atrophy in familial Alzheimer disease: volumetric MRI results from the DIAN study.Does Alzheimer's disease begin in the brainstem?Familial Alzheimer's disease-associated presenilin-1 alters cerebellar activity and calcium homeostasis.Role of biochemical Alzheimer's disease biomarkers as end points in clinical trials.Amyloid precursor protein processing and Alzheimer's diseasePresenilins function in ER calcium leak and Alzheimer's disease pathogenesis.Presenilins as endoplasmic reticulum calcium leak channels and Alzheimer's disease pathogenesis.The senescence hypothesis of disease progression in Alzheimer disease: an integrated matrix of disease pathways for FAD and SAD.Biological function of Presenilin and its role in AD pathogenesisThe Existence of Primary Age-Related Tauopathy Suggests that not all the Cases with Early Braak Stages of Neurofibrillary Pathology are Alzheimer's Disease.The DIAN-TU Next Generation Alzheimer's prevention trial: Adaptive design and disease progression model.Alzheimer's disease pathological lesions activate the spleen tyrosine kinase.Understanding the roles of mutations in the amyloid precursor protein in Alzheimer disease.P-glycoprotein (ABCB1) and Oxidative Stress: Focus on Alzheimer's Disease.APP mutations in the Aβ coding region are associated with abundant cerebral deposition of Aβ38.The Effects of Gene Mutations on Default Mode Network in Familial Alzheimer's Disease.AβPP/PS1 Transgenic Mice Show Sex Differences in the Cerebellum Associated with Aging.On the role of sidechain size and charge in the aggregation of A42 with familial mutationsExposure to Environmental and Occupational Particulate Air Pollution as a Potential Contributor to Neurodegeneration and Diabetes: A Systematic Review of Epidemiological Research
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Variations in the neuropathology of familial Alzheimer's disease.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on 22 March 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Variations in the neuropathology of familial Alzheimer's disease.
@en
Variations in the neuropathology of familial Alzheimer's disease.
@nl
type
label
Variations in the neuropathology of familial Alzheimer's disease.
@en
Variations in the neuropathology of familial Alzheimer's disease.
@nl
prefLabel
Variations in the neuropathology of familial Alzheimer's disease.
@en
Variations in the neuropathology of familial Alzheimer's disease.
@nl
P1476
Variations in the neuropathology of familial Alzheimer's disease.
@en
P2093
Heather McCann
P2888
P356
10.1007/S00401-009-0521-4
P577
2009-03-22T00:00:00Z