Inhibition of heterotrimeric G protein signaling by a small molecule acting on Galpha subunit. - Wikidata - awgldk - TriplyDB

Inhibition of heterotrimeric G protein signaling by a small molecule acting on Galpha subunit.

Inhibition of heterotrimeric G protein signaling by a small molecule acting on Galpha subunit.

http://www.wikidata.org/entity/Q37431269

about

Calcium-sensing receptors signal constitutive macropinocytosis and facilitate the uptake of NOD2 ligands in macrophages.The oligomeric state sets GABA(B) receptor signalling efficacy Ligand-based peptide design and combinatorial peptide libraries to target G protein-coupled receptors Inhibitory G proteins and their receptors: emerging therapeutic targets for obesity and diabetes.A critical role of Gbetagamma in tumorigenesis and metastasis of breast cancer.Atypical signaling and functional desensitization response of MAS receptor to peptide ligands.Functional interaction between angiotensin II receptor type 1 and chemokine (C-C motif) receptor 2 with implications for chronic kidney disease Assessing Gonadotropin Receptor Function by Resonance Energy Transfer-Based Assays.Heteromeric MT1/MT2 melatonin receptors modulate photoreceptor function.Interaction of Protease-Activated Receptor 2 with G Proteins and β-Arrestin 1 Studied by Bioluminescence Resonance Energy Transfer.Probing heterotrimeric G protein activation: applications to biased ligands.BRET biosensors to study GPCR biology, pharmacology, and signal transduction.Molecular targeting of Gα and Gβγ subunits: a potential approach for cancer therapeutics.Biophysical Detection of Diversity and Bias in GPCR Function.Genetic, structural, and molecular insights into the function of ras of complex proteins domains.A cell-permeable inhibitor to trap Gαq proteins in the empty pocket conformation.Crosstalk between angiotensin and the nonamyloidogenic pathway of Alzheimer's amyloid precursor protein.The Gαi-GIV binding interface is a druggable protein-protein interaction Lysophosphatidic acid increases proximal tubule cell secretion of profibrotic cytokines PDGF-B and CTGF through LPA2- and Gαq-mediated Rho and αvβ6 integrin-dependent activation of TGF-β Receptor-G protein interaction studied by bioluminescence resonance energy transfer: lessons from protease-activated receptor 1.The vasoactive peptides urotensin II and urotensin II-related peptide regulate astrocyte activity through common and distinct mechanisms: involvement in cell proliferation.Potent and Selective Peptide-based Inhibition of the G Protein Gαq.Molecular Approaches To Target GPCRs in Cancer Therapy.Bruton's tyrosine kinase and RAC1 promote cell survival in MLL-rearranged acute myeloid leukemia.

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P2860

Inhibition of heterotrimeric G protein signaling by a small molecule acting on Galpha subunit.

http://www.wikidata.org/entity/Q37431269

description

article científic

@ca

article scientifique

@fr

articolo scientifico

@it

artigo científico

@pt

bilimsel makale

@tr

scientific article published on 31 July 2009

@en

vedecký článok

@sk

vetenskaplig artikel

@sv

videnskabelig artikel

@da

vědecký článek

@cs

name

Inhibition of heterotrimeric G ...... cule acting on Galpha subunit.

@en

Inhibition of heterotrimeric G ...... cule acting on Galpha subunit.

@nl

type

label

Inhibition of heterotrimeric G ...... cule acting on Galpha subunit.

@en

Inhibition of heterotrimeric G ...... cule acting on Galpha subunit.

@nl

prefLabel

Inhibition of heterotrimeric G ...... cule acting on Galpha subunit.

@en

Inhibition of heterotrimeric G ...... cule acting on Galpha subunit.

@nl

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P356

JBC.M109.042333

P1433

Journal of Biological Chemistry

P1476

Inhibition of heterotrimeric G ...... cule acting on Galpha subunit.

@en

P2093

Christian Gespach

http://www.w3.org/2001/XMLSchema#string

Eric Ferrandis

http://www.w3.org/2001/XMLSchema#string

Grégoire Pierre Prévost

http://www.w3.org/2001/XMLSchema#string

Jean-Louis Banères

http://www.w3.org/2001/XMLSchema#string

Jean-Philippe Pin

http://www.w3.org/2001/XMLSchema#string

Marjorie Damian

http://www.w3.org/2001/XMLSchema#string

Mohammed Akli Ayoub

http://www.w3.org/2001/XMLSchema#string

Olivier De Wever

http://www.w3.org/2001/XMLSchema#string

Olivier Lavergne

http://www.w3.org/2001/XMLSchema#string

P2860

Heterotrimeric G proteins precouple with G protein-coupled receptors in living cells.

Monitoring of ligand-independent dimerization and ligand-induced conformational changes of melatonin receptors in living cells by bioluminescence resonance energy transfer

How many drug targets are there?

Proinvasive activity of BMP-7 through SMAD4/src-independent and ERK/Rac/JNK-dependent signaling pathways in colon cancer cells

Structure-based analysis of GPCR function: evidence for a novel pentameric assembly between the dimeric leukotriene B4 receptor BLT1 and the G-protein.

Pharmacology. Hitting the hot spots of cell signaling cascades.

Differential targeting of Gbetagamma-subunit signaling with small molecules.

Latest development in drug discovery on G protein-coupled receptors.

G proteins as drug targets.

G protein antagonists.

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29136-29145

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scholarly article

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10.1074/JBC.M109.042333

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P433

42

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284

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2009-07-31T00:00:00Z

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19648112

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2781458

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