JNK/FOXO-mediated neuronal expression of fly homologue of peroxiredoxin II reduces oxidative stress and extends life span.
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Genetics and epigenetics of aging and longevityTrpA1 Regulates Defecation of Food-Borne Pathogens under the Control of the Duox PathwayLifespan extension by preserving proliferative homeostasis in DrosophilaEnhanced neuronal glucose transporter expression reveals metabolic choice in a HD Drosophila modelThe nitric oxide-cyclic GMP pathway regulates FoxO and alters dopaminergic neuron survival in DrosophilaA Drosophila ABC transporter regulates lifespanA novel MitoTimer reporter gene for mitochondrial content, structure, stress, and damage in vivo.Whole transcriptome analysis of a reversible neurodegenerative process in Drosophila reveals potential neuroprotective genes.Light-sensing via hydrogen peroxide and a peroxiredoxin.FoxO and stress responses in the cnidarian Hydra vulgaris.Neuronal expression of Mgat1 rescues the shortened life span of Drosophila Mgat11 null mutants and increases life spanAging and brain rejuvenation as systemic events.Iron and mechanisms of neurotoxicityRedox regulation by Keap1 and Nrf2 controls intestinal stem cell proliferation in DrosophilaRegulation of Drosophila lifespan by JNK signalingIGF-1-induced enhancement of PRNP expression depends on the negative regulation of transcription factor FOXO3a.FoxO4 inhibits atherosclerosis through its function in bone marrow derived cells.FoxO limits microtubule stability and is itself negatively regulated by microtubule disruptionOvotoxicants 4-vinylcyclohexene 1,2-monoepoxide and 4-vinylcyclohexene diepoxide disrupt redox status and modify different electrophile sensitive target enzymes and genes in Drosophila melanogasterOverexpression of fatty-acid-β-oxidation-related genes extends the lifespan of Drosophila melanogasterROS regulation of axonal mitochondrial transport is mediated by Ca2+ and JNK in DrosophilaGenetic modifier screens to identify components of a redox-regulated cell adhesion and migration pathwayOxidative Stress Promotes Peroxiredoxin Hyperoxidation and Attenuates Pro-survival Signaling in Aging Chondrocytes.Cordycepin Prevents Bone Loss through Inhibiting Osteoclastogenesis by Scavenging ROS Generation.Involvement of redox state in the aging of Drosophila melanogaster.Role of reactive oxygen species-mediated signaling in aging.Dmp53, basket and drICE gene knockdown and polyphenol gallic acid increase life span and locomotor activity in a Drosophila Parkinson's disease model.Prenatal hyperbaric normoxia treatment improves healthspan and regulates chitin metabolic genes in Drosophila melanogaster.Resveratrol accelerates erythroid maturation by activation of FoxO3 and ameliorates anemia in beta-thalassemic mice.Dysregulated FOXO transcription factors in articular cartilage in aging and osteoarthritis.Joint inhibition of TOR and JNK pathways interacts to extend the lifespan of Brachionus manjavacas (Rotifera).Forkhead homeobox type O transcription factors in the responses to oxidative stress.Oxidative stress in synapse development and function.The antioxidant enzyme peroxiredoxin and its protective role in neurological disorders.Peroxiredoxins, gerontogenes linking aging to genome instability and cancer.Neuronal responses to physiological stress.Linking Peroxiredoxin and Vacuolar-ATPase Functions in Calorie Restriction-Mediated Life Span Extension.Reproducible effects of the mitochondria-targeted plastoquinone derivative SkQ1 on Drosophila melanogaster lifespan under different experimental scenarios.Urm1: an essential regulator of JNK signaling and oxidative stress in Drosophila melanogaster.A peroxiredoxin, PRDX-2, is required for insulin secretion and insulin/IIS-dependent regulation of stress resistance and longevity.
P2860
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P2860
JNK/FOXO-mediated neuronal expression of fly homologue of peroxiredoxin II reduces oxidative stress and extends life span.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 31 August 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
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name
JNK/FOXO-mediated neuronal exp ...... stress and extends life span.
@en
JNK/FOXO-mediated neuronal exp ...... stress and extends life span.
@nl
type
label
JNK/FOXO-mediated neuronal exp ...... stress and extends life span.
@en
JNK/FOXO-mediated neuronal exp ...... stress and extends life span.
@nl
prefLabel
JNK/FOXO-mediated neuronal exp ...... stress and extends life span.
@en
JNK/FOXO-mediated neuronal exp ...... stress and extends life span.
@nl
P2093
P2860
P356
P1476
JNK/FOXO-mediated neuronal exp ...... stress and extends life span.
@en
P2093
Dong-Seok Lee
Joon H Lee
Kanae Iijima-Ando
Koichi Iijima
Kyu-Sun Lee
Won-Jae Lee
P2860
P304
29454-29461
P356
10.1074/JBC.M109.028027
P407
P577
2009-08-31T00:00:00Z