Ligand and structure-based methodologies for the prediction of the activity of G protein-coupled receptor ligands
about
Invited review: GPCR structural characterization: Using fragments as building blocks to determine a complete structure.Ligand and structure-based models for the prediction of ligand-receptor affinities and virtual screenings: Development and application to the beta(2)-adrenergic receptorAn unbiased method to build benchmarking sets for ligand-based virtual screening and its application to GPCRsThe use of G-protein coupled receptor models in lead optimization.Computational ligand-based rational design: Role of conformational sampling and force fields in model development.Current progress in Structure-Based Rational Drug Design marks a new mindset in drug discoveryMedicinal chemistry of the A3 adenosine receptor: agonists, antagonists, and receptor engineering.Predicting the biological activities through QSAR analysis and docking-based scoring.Structure-activity relationships and molecular modeling of 1,2,4-triazoles as adenosine receptor antagonistsMolecular docking and 3D-QSAR-based virtual screening of flavonoids as potential aromatase inhibitors against estrogen-dependent breast cancer.Comparative docking study of anibamine as the first natural product CCR5 antagonist in CCR5 homology models.GPCR Homology Model Generation for Lead Optimization.
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Ligand and structure-based methodologies for the prediction of the activity of G protein-coupled receptor ligands
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 16 May 2008
@en
vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Ligand and structure-based met ...... otein-coupled receptor ligands
@en
Ligand and structure-based met ...... tein-coupled receptor ligands.
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type
label
Ligand and structure-based met ...... otein-coupled receptor ligands
@en
Ligand and structure-based met ...... tein-coupled receptor ligands.
@nl
prefLabel
Ligand and structure-based met ...... otein-coupled receptor ligands
@en
Ligand and structure-based met ...... tein-coupled receptor ligands.
@nl
P2860
P1476
Ligand and structure-based met ...... otein-coupled receptor ligands
@en
P2093
Irina G Tikhonova
T Kendall Harden
P2860
P2888
P304
P356
10.1007/S10822-008-9218-3
P577
2008-05-16T00:00:00Z