Photodamage generates 7-keto- and 7-hydroxycholesterol in the rat retina via a free radical-mediated mechanism.
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7-Dehydrocholesterol-derived oxysterols and retinal degeneration in a rat model of Smith-Lemli-Opitz syndromeCholesterol oxidation in the retina: implications of 7KCh formation in chronic inflammation and age-related macular degeneration7-ketocholesterol-induced inflammation: involvement of multiple kinase signaling pathways via NFκB but independently of reactive oxygen species formationConversion of 7-ketocholesterol to oxysterol metabolites by recombinant CYP27A1 and retinal pigment epithelial cells.7-Ketocholesterol increases retinal microglial migration, activation, and angiogenicity: a potential pathogenic mechanism underlying age-related macular degenerationNovel oxysterols observed in tissues and fluids of AY9944-treated rats: a model for Smith-Lemli-Opitz syndrome.Free radical oxidation of cholesterol and its precursors: Implications in cholesterol biosynthesis disorders.Examining the role of lipid mediators in diabetic retinopathy.Pretreatment with pyridoxamine mitigates isolevuglandin-associated retinal effects in mice exposed to bright light.Retinal light damage: mechanisms and protection.Probes for protein adduction in cholesterol biosynthesis disorders: Alkynyl lanosterol as a viable sterol precursor.Conversion of 7-dehydrocholesterol to 7-ketocholesterol is catalyzed by human cytochrome P450 7A1 and occurs by direct oxidation without an epoxide intermediate.The role of dyslipidemia in diabetic retinopathy.Bestrophinopathy: An RPE-photoreceptor interface disease.Evidence for altered cholesterol metabolism in Huntington's disease post mortem brain tissue.A reduced zinc diet or zinc transporter 3 knockout attenuate light induced zinc accumulation and retinal degeneration.Brain Cholesterol Synthesis and Metabolism is Progressively Disturbed in the R6/1 Mouse Model of Huntington's Disease: A Targeted GC-MS/MS Sterol Analysis.Propagation rate constants for the peroxidation of sterols on the biosynthetic pathway to cholesterol.Effect of sevoflurane preconditioning on light-induced retinal damage in diabetic rats.Oxysterols and Retinal Degeneration in a Rat Model of Smith-Lemli-Opitz Syndrome: Implications for an Improved Therapeutic Intervention
P2860
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P2860
Photodamage generates 7-keto- and 7-hydroxycholesterol in the rat retina via a free radical-mediated mechanism.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 20 May 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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Photodamage generates 7-keto- ...... ee radical-mediated mechanism.
@en
Photodamage generates 7-keto- ...... ee radical-mediated mechanism.
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type
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Photodamage generates 7-keto- ...... ee radical-mediated mechanism.
@en
Photodamage generates 7-keto- ...... ee radical-mediated mechanism.
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Photodamage generates 7-keto- ...... ee radical-mediated mechanism.
@en
Photodamage generates 7-keto- ...... ee radical-mediated mechanism.
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P2860
P1476
Photodamage generates 7-keto- ...... ee radical-mediated mechanism.
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P2093
Ignacio R Rodriguez
Steven J Fliesler
P2860
P304
P356
10.1111/J.1751-1097.2009.00568.X
P577
2009-05-20T00:00:00Z