Hsp90, not Grp94, regulates the intracellular trafficking and stability of nascent ErbB2
about
A human MAP kinase interactomeIntegrin alphavbeta3, requirement for VEGFR2-mediated activation of SAPK2/p38 and for Hsp90-dependent phosphorylation of focal adhesion kinase in endothelial cells activated by VEGFTargeting Hsp90 in urothelial carcinomaParalog-selective Hsp90 inhibitors define tumor-specific regulation of HER2Contribution of chaperones to STAT pathway signaling.Direct activation of HSP90A transcription by c-Myc contributes to c-Myc-induced transformationAssociation between Hsp90 and the ClC-2 chloride channel upregulates channel functionMarked enhancement of lysosomal targeting and efficacy of ErbB2-targeted drug delivery by HSP90 inhibitionSerum HER-2 concentration is associated with insulin resistance and decreases after weight loss.Drug-induced ubiquitylation and degradation of ErbB receptor tyrosine kinases: implications for cancer therapy.Chaperone-dependent E3 ubiquitin ligase CHIP mediates a degradative pathway for c-ErbB2/Neu.Role of Erbin in ErbB2-dependent breast tumor growth.Geldanamycin selectively targets the nascent form of ERBB3 for degradationPnck induces ligand-independent EGFR degradation by probable perturbation of the Hsp90 chaperone complex.Anaplastic lymphoma kinase and its signalling molecules as novel targets in lymphoma therapy.HSP90 inhibitor 17-AAG selectively eradicates lymphoma stem cells.Sensitivity of epidermal growth factor receptor and ErbB2 exon 20 insertion mutants to Hsp90 inhibitionEnzymatic reduction and glutathione conjugation of benzoquinone ansamycin heat shock protein 90 inhibitors: relevance for toxicity and mechanism of action.Stability of the Hsp90 inhibitor 17AAG hydroquinone and prevention of metal-catalyzed oxidation.Enzyme specific activation of benzoquinone ansamycin prodrugs using HuCC49DeltaCH2-beta-galactosidase conjugatesThe chaperones Hsp90 and Cdc37 mediate the maturation and stabilization of protein kinase C through a conserved PXXP motif in the C-terminal tail.The role of Neuregulin-1beta/ErbB signaling in the heart.Impact of heat-shock protein 90 on cancer metastasisNovobiocin and additional inhibitors of the Hsp90 C-terminal nucleotide-binding pocket.Rab11-FIP1C Is a Critical Negative Regulator in ErbB2-Mediated Mammary Tumor ProgressionNovel therapeutic strategies in multiple myeloma: role of the heat shock protein inhibitors.Use of ultraviolet-light irradiated multiple myeloma cells as immunogens to generate tumor-specific cytolytic T lymphocytes.Expression levels of heat shock proteins in enterocyte-like Caco-2 cells after exposure to Salmonella enteritidis.The platelet-derived growth factor receptor alpha is destabilized by geldanamycins in cancer cells.Antimyeloma activity of heat shock protein-90 inhibition.Heat shock protein 90 associates with Toll-like receptors 7/9 and mediates self-nucleic acid recognition in SLE.Enantioselective effect of bifenthrin on antioxidant enzyme gene expression and stress protein response in PC12 cells.5'-N-ethylcarboxamidoadenosine is not a paralog-specific Hsp90 inhibitor.STK33 participates to HSP90-supported angiogenic program in hypoxic tumors by regulating HIF-1α/VEGF signaling pathway.
P2860
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P2860
Hsp90, not Grp94, regulates the intracellular trafficking and stability of nascent ErbB2
description
article científic
@ca
article scientifique
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articolo scientifico
@it
artigo científico
@pt
bilimsel makale
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scientific article published on January 2002
@en
vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Hsp90, not Grp94, regulates the intracellular trafficking and stability of nascent ErbB2
@en
Hsp90, not Grp94, regulates the intracellular trafficking and stability of nascent ErbB2.
@nl
type
label
Hsp90, not Grp94, regulates the intracellular trafficking and stability of nascent ErbB2
@en
Hsp90, not Grp94, regulates the intracellular trafficking and stability of nascent ErbB2.
@nl
prefLabel
Hsp90, not Grp94, regulates the intracellular trafficking and stability of nascent ErbB2
@en
Hsp90, not Grp94, regulates the intracellular trafficking and stability of nascent ErbB2.
@nl
P2093
P2860
P1476
Hsp90, not Grp94, regulates the intracellular trafficking and stability of nascent ErbB2
@en
P2093
Edward G Mimnaugh
Jane B Trepel
Jung-Sik Kim
Leonard M Neckers
Wanping Xu
P2860
P356
10.1379/1466-1268(2002)007<0091:HNGRTI>2.0.CO;2
P577
2002-01-01T00:00:00Z