The platelet-derived growth factor receptor alpha is destabilized by geldanamycins in cancer cells.
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The cilia-regulated proteasome and its role in the development of ciliopathies and cancerContribution of chaperones to STAT pathway signaling.Biologic effects of platelet-derived growth factor receptor α blockade in uterine cancer.Validation of a high-content screening assay using whole-well imaging of transformed phenotypes.Cell surface Cdc37 participates in extracellular HSP90 mediated cancer cell invasionA first in human, safety, pharmacokinetics, and clinical activity phase I study of once weekly administration of the Hsp90 inhibitor ganetespib (STA-9090) in patients with solid malignancies.Gastrointestinal stromal tumor - an evolving concept.Emodin suppresses maintenance of stemness by augmenting proteosomal degradation of epidermal growth factor receptor/epidermal growth factor receptor variant III in glioma stem cells.Impact of heat-shock protein 90 on cancer metastasisHeat shock proteins in antigen trafficking--implications on antigen presentation to T cells.Hsp90 as a gatekeeper of tumor angiogenesis: clinical promise and potential pitfalls.Chlamydia-infected cells shed Gp96 to prevent chlamydial re-infection.Systemic therapy for advanced gastrointestinal stromal tumors: beyond imatinib.Gastrointestinal stromal tumors: what do we know now?Restoring TRAIL mediated signaling in ovarian cancer cells.Radioresistant human lung adenocarcinoma cells that survived multiple fractions of ionizing radiation are sensitive to HSP90 inhibition17-Allylamino-17-Demethoxygeldanamycin and the Enhancement of PS-341-Induced Lung Cancer Cell Death by Blocking the NF-κB and PI3K/Akt Pathways.Antitumor activity of NVP-AUY922, a novel heat shock protein 90 inhibitor, in human gastric cancer cells is mediated through proteasomal degradation of client proteins.Design and synthesis of Hsp90 inhibitors: exploring the SAR of Sansalvamide A derivatives.Macrocycles that inhibit the binding between heat shock protein 90 and TPR-containing proteins.Targeting heat-shock protein 90 improves efficacy of rapamycin in a model of hepatocellular carcinoma in mice.Akt shows variable sensitivity to an Hsp90 inhibitor depending on cell context.Synthesis of sansalvamide A peptidomimetics: triazole, oxazole, thiazole, and pseudoproline containing compounds.A heat shock protein 90 inhibitor that modulates the immunophilins and regulates hormone receptors without inducing the heat shock responseIntracellular alpha-synuclein affects early maturation of primary oligodendrocyte progenitor cellsMolecular mechanism of 17-allylamino-17-demethoxygeldanamycin (17-AAG)-induced AXL receptor tyrosine kinase degradation.Evaluation of di-sansalvamide A derivatives: synthesis, structure-activity relationship, and mechanism of actionMechanistic studies of Sansalvamide A-amide: an allosteric modulator of Hsp90.Synthesis and evaluation of biotinylated sansalvamide A analogs and their modulation of Hsp90.Dimerization of a heat shock protein 90 inhibitor enhances inhibitory activity.Heat shock factor 1 confers resistance to lapatinib in ERBB2-positive breast cancer cells.
P2860
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P2860
The platelet-derived growth factor receptor alpha is destabilized by geldanamycins in cancer cells.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
The platelet-derived growth fa ...... geldanamycins in cancer cells.
@en
type
label
The platelet-derived growth fa ...... geldanamycins in cancer cells.
@en
prefLabel
The platelet-derived growth fa ...... geldanamycins in cancer cells.
@en
P2093
P2860
P356
P1476
The platelet-derived growth fa ...... geldanamycins in cancer cells
@en
P2093
David B Donner
Minati Satpathy
Yi-Chun Lai
P2860
P304
P356
10.1074/JBC.M607012200
P407
P577
2006-11-01T00:00:00Z