Efficient immortalization of luminal epithelial cells from human mammary gland by introduction of simian virus 40 large tumor antigen with a recombinant retrovirus
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A novel gene (PLU-1) containing highly conserved putative DNA/chromatin binding motifs is specifically up-regulated in breast cancerEpigenetic CRBP downregulation appears to be an evolutionarily conserved (human and mouse) and oncogene-specific phenomenon in breast cancerMammary epithelial cell transformation: insights from cell culture and mouse models.Purification and characterization of a complex containing matriptase and a Kunitz-type serine protease inhibitor from human milkSpecific association of CD63 with the VLA-3 and VLA-6 integrinsThe relative activities of the C2GnT1 and ST3Gal-I glycosyltransferases determine O-glycan structure and expression of a tumor-associated epitope on MUC1.Stem cells in the human breastTissue architecture and breast cancer: the role of extracellular matrix and steroid hormonesThe importance of the microenvironment in breast cancer progression: recapitulation of mammary tumorigenesis using a unique human mammary epithelial cell model and a three-dimensional culture assay.PLU-1 nuclear protein, which is upregulated in breast cancer, shows restricted expression in normal human adult tissues: a new cancer/testis antigen?Immortalization of distinct human mammary epithelial cell types by human papilloma virus 16 E6 or E7.A cohesin-independent role for NIPBL at promoters provides insights in CdLS.The ST6GalNAc-I sialyltransferase localizes throughout the Golgi and is responsible for the synthesis of the tumor-associated sialyl-Tn O-glycan in human breast cancer.hTERT extends the life of human fibroblasts without compromising type I interferon signaling.HTLV-1 Tax oncoprotein inhibits the estrogen-induced-ER α-Mediated BRCA1 expression by interaction with CBP/p300 cofactors.Differential subcellular localization renders HAI-2 a matriptase inhibitor in breast cancer cells but not in mammary epithelial cellsChoosing a mouse model: experimental biology in context--the utility and limitations of mouse models of breast cancer.Modelling breast cancer requires identification and correction of a critical cell lineage-dependent transduction biasOverexpression of ERBB2 in human mammary epithelial cells signals inhibition of transcription of the E-cadherin geneDevelopment and characterisation of a 3D multi-cellular in vitro model of normal human breast: a tool for cancer initiation studiesMalignant progression of SV40-immortalised human milk epithelial cells.Matriptase Complexes and Prostasin Complexes with HAI-1 and HAI-2 in Human Milk: Significant Proteolysis in LactationExpression of the ERBB3 gene product in breast cancer.Regulation of Wnt5a expression in human mammary cells by protein kinase C activity and the cytoskeletonDefective interleukin six expression and responsiveness in human mammary cells transformed by an adeno 5/SV40 hybrid virus.Natural Endogenous Human Matriptase and Prostasin Undergo Zymogen Activation via Independent Mechanisms in an Uncoupled Manner.DNA tumor virus oncoproteins and retinoblastoma gene mutations share the ability to relieve the cell's requirement for cyclin D1 function in G1p53-dependent and p53-independent activation of apoptosis in mammary epithelial cells reveals a survival function of EGF and insulin.A transfected sialyltransferase that is elevated in breast cancer and localizes to the medial/trans-Golgi apparatus inhibits the development of core-2-based O-glycans.Functional analysis of the transcription repressor PLU-1/JARID1B.c-erbB-3: a nuclear protein in mammary epithelial cells.Alterations in p53 and p16INK4 expression and telomere length during spontaneous immortalization of Li-Fraumeni syndrome fibroblastsSp1 binding plays a critical role in Erb-B2- and v-ras-mediated downregulation of alpha2-integrin expression in human mammary epithelial cells.Apoptosis of estrogen-receptor negative breast cancer and colon cancer cell lines by PTP alpha and src RNAi.Regulation of epidermal growth factor receptor signaling by endocytosis and intracellular traffickingDifferential effects of HTLV-1 Tax oncoprotein on the different estrogen-induced-ER α-mediated transcriptional activities.Characterization of novel complexes on the cell surface between integrins and proteins with 4 transmembrane domains (TM4 proteins).BRCA1-dependent ubiquitination of gamma-tubulin regulates centrosome numberCytogenetic characterization of HB2 epithelial cells from the human breast.A formylated hexapeptide ligand mimics the ability of Wnt-5a to impair migration of human breast epithelial cells.
P2860
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P2860
Efficient immortalization of luminal epithelial cells from human mammary gland by introduction of simian virus 40 large tumor antigen with a recombinant retrovirus
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on May 1991
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Efficient immortalization of l ...... with a recombinant retrovirus
@en
Efficient immortalization of l ...... with a recombinant retrovirus.
@nl
type
label
Efficient immortalization of l ...... with a recombinant retrovirus
@en
Efficient immortalization of l ...... with a recombinant retrovirus.
@nl
prefLabel
Efficient immortalization of l ...... with a recombinant retrovirus
@en
Efficient immortalization of l ...... with a recombinant retrovirus.
@nl
P2093
P2860
P4510
P356
P1476
Efficient immortalization of l ...... with a recombinant retrovirus
@en
P2093
Bartkova J
Kyprianou N
Staskova Z
Taylor-Papadimitriou J
P2860
P304
P356
10.1073/PNAS.88.9.3520
P407
P577
1991-05-01T00:00:00Z