BRCA1-dependent ubiquitination of gamma-tubulin regulates centrosome number
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Centrosome-associated regulators of the G(2)/M checkpoint as targets for cancer therapyBRCA1/BARD1 inhibition of mRNA 3' processing involves targeted degradation of RNA polymerase II.The UBXN1 protein associates with autoubiquitinated forms of the BRCA1 tumor suppressor and inhibits its enzymatic functionKIAA0101 interacts with BRCA1 and regulates centrosome numberActivity-enhancing mutations in an E3 ubiquitin ligase identified by high-throughput mutagenesisA novel role for BRCA1 in regulating breast cancer cell spreading and motilityNEDD1-dependent recruitment of the gamma-tubulin ring complex to the centrosome is necessary for centriole duplication and spindle assemblyGlobal approaches to understanding ubiquitination.A guide for functional analysis of BRCA1 variants of uncertain significanceThe BRCA1 Breast Cancer Suppressor: Regulation of Transport, Dynamics, and Function at Multiple Subcellular LocationsDrugging the addict: non-oncogene addiction as a target for cancer therapyIs there more to BARD1 than BRCA1?BRCA1 and Oxidative StressBRCA1 targets G2/M cell cycle proteins for ubiquitination and proteasomal degradationBRCA1 deficiency in skin epidermis leads to selective loss of hair follicle stem cells and their progenyEstrogen mediates Aurora-A overexpression, centrosome amplification, chromosomal instability, and breast cancer in female ACI ratsHomologs of breast cancer genes in plantsBRCA1 foci in normal S-phase nuclei are linked to interphase centromeres and replication of pericentric heterochromatin.The relative efficiency of homology-directed repair has distinct effects on proper anaphase chromosome separation.Genetic analysis of BRCA1 ubiquitin ligase activity and its relationship to breast cancer susceptibility.The UPS: a promising target for breast cancer treatment.BRCA1 represses amphiregulin gene expression.Non-visual arrestins are constitutively associated with the centrosome and regulate centrosome function.Identification of Saccharomyces cerevisiae spindle pole body remodeling factorsBRCA1 controls the cell division axis and governs ploidy and phenotype in human mammary cells.BRCA1 haploinsufficiency leads to altered expression of genes involved in cellular proliferation and development.Bcr/Abl interferes with the Fanconi anemia/BRCA pathway: implications in the chromosomal instability of chronic myeloid leukemia cells.E2F activators signal and maintain centrosome amplification in breast cancer cells.Causes and consequences of centrosome abnormalities in cancer.Weighing in on ubiquitin: the expanding role of mass-spectrometry-based proteomics.Interplay between BRCA1 and RHAMM regulates epithelial apicobasal polarization and may influence risk of breast cancer.Microtubule-associated protein Mdp3 promotes breast cancer growth and metastasisCentrosomal microtubule nucleation activity is inhibited by BRCA1-dependent ubiquitinationBRCA1 and BRCA2: breast/ovarian cancer susceptibility gene products and participants in DNA double-strand break repair.Identification of breast tumor mutations in BRCA1 that abolish its function in homologous DNA recombination.BP1, an isoform of DLX4 homeoprotein, negatively regulates BRCA1 in sporadic breast cancerAssociation of BRCA1 and BRCA2 mutations with survival, chemotherapy sensitivity, and gene mutator phenotype in patients with ovarian cancerDiffering clinical impact of BRCA1 and BRCA2 mutations in serous ovarian cancer.DNA double-strand break signaling and human disorders.Weighted frequent gene co-expression network mining to identify genes involved in genome stability.
P2860
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P2860
BRCA1-dependent ubiquitination of gamma-tubulin regulates centrosome number
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on October 2004
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
@cs
name
BRCA1-dependent ubiquitination of gamma-tubulin regulates centrosome number
@en
BRCA1-dependent ubiquitination of gamma-tubulin regulates centrosome number.
@nl
type
label
BRCA1-dependent ubiquitination of gamma-tubulin regulates centrosome number
@en
BRCA1-dependent ubiquitination of gamma-tubulin regulates centrosome number.
@nl
prefLabel
BRCA1-dependent ubiquitination of gamma-tubulin regulates centrosome number
@en
BRCA1-dependent ubiquitination of gamma-tubulin regulates centrosome number.
@nl
P2093
P2860
P1476
BRCA1-dependent ubiquitination of gamma-tubulin regulates centrosome number
@en
P2093
Brian P Schlegel
Jeffrey D Parvin
Joshua E Elias
Karen Griffin
Lea M Starita
Satish Sankaran
Yuka Machida
P2860
P304
P356
10.1128/MCB.24.19.8457-8466.2004
P407
P577
2004-10-01T00:00:00Z