Checkpoint mechanisms at the intersection between DNA damage and repair.
about
NUDT16 is a (deoxy)inosine diphosphatase, and its deficiency induces accumulation of single-strand breaks in nuclear DNA and growth arrestDynamics of DNA damage response proteins at DNA breaks: a focus on protein modificationsThe DNA damage response induced by infection with human cytomegalovirus and other virusesSlx4 and Rtt107 control checkpoint signalling and DNA resection at double-strand breaks.Radiation microbeams as spatial and temporal probes of subcellular and tissue response.Elevated levels of the polo kinase Cdc5 override the Mec1/ATR checkpoint in budding yeast by acting at different steps of the signaling pathway.The oncogenic phosphatase WIP1 negatively regulates nucleotide excision repairGenomic instability, defective spermatogenesis, immunodeficiency, and cancer in a mouse model of the RIDDLE syndromeDynamics of Rad9 chromatin binding and checkpoint function are mediated by its dimerization and are cell cycle-regulated by CDK1 activityCCAAT/enhancer binding protein delta (C/EBPdelta, CEBPD)-mediated nuclear import of FANCD2 by IPO4 augments cellular response to DNA damage.Loss of CCDC6, the first identified RET partner gene, affects pH2AX S139 levels and accelerates mitotic entry upon DNA damage.DNA methyltransferases, DNA damage repair, and cancerIn vivo and in silico analysis of PCNA ubiquitylation in the activation of the Post Replication Repair pathway in S. cerevisiae.The co-repressor SMRT delays DNA damage-induced caspase activation by repressing pro-apoptotic genes and modulating the dynamics of checkpoint kinase 2 activation.Reduction of hRNase H2 activity in Aicardi-Goutières syndrome cells leads to replication stress and genome instabilityThe role of RAD9 in tumorigenesis.Human exonuclease 1 connects nucleotide excision repair (NER) processing with checkpoint activation in response to UV irradiation.Adaptation to P element transposon invasion in Drosophila melanogaster.RNase H and postreplication repair protect cells from ribonucleotides incorporated in DNAContributions of Rad9 to tumorigenesis.AT1R blockade in adverse milieus: role of SMRT and corepressor complexes.CCT244747 is a novel potent and selective CHK1 inhibitor with oral efficacy alone and in combination with genotoxic anticancer drugs.Mature microsatellites: mechanisms underlying dinucleotide microsatellite mutational biases in human cells.The mechanism of nucleotide excision repair-mediated UV-induced mutagenesis in nonproliferating cells.DNA Replication Stress Phosphoproteome Profiles Reveal Novel Functional Phosphorylation Sites on Xrs2 in Saccharomyces cerevisiaePrinciples and concepts of DNA replication in bacteria, archaea, and eukarya.Cell-cycle and DNA damage regulation of the DNA mismatch repair protein Msh2 occurs at the transcriptional and post-transcriptional level.Regulation of endonuclease activity in human nucleotide excision repair.Mind the gap: keeping UV lesions in check.Epigenetic regulation of genomic integrity.DNA damage response in plants: conserved and variable response compared to animals.ATR- and ATM-Mediated DNA Damage Response Is Dependent on Excision Repair Assembly during G1 but Not in S Phase of Cell Cycle.Initiation of the ATM-Chk2 DNA damage response through the base excision repair pathway.A potent Chk1 inhibitor is selectively cytotoxic in melanomas with high levels of replicative stress.The preference for error-free or error-prone postreplication repair in Saccharomyces cerevisiae exposed to low-dose methyl methanesulfonate is cell cycle dependent.Break-induced ATR and Ddb1-Cul4(Cdt)² ubiquitin ligase-dependent nucleotide synthesis promotes homologous recombination repair in fission yeast.Immunohistochemical analysis of mismatch proteins in carcinogenesis of the lower lip.RAD-6: pyrimidine synthesis and radiation sensitivity in Caenorhabditis elegans.Proteomic identification of histone post-translational modifications and proteins enriched at a DNA double-strand break.Recruitment kinetics of the homologous recombination pathway in procyclic forms of Trypanosoma brucei after ionizing radiation treatment.
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Checkpoint mechanisms at the intersection between DNA damage and repair.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on 03 June 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Checkpoint mechanisms at the intersection between DNA damage and repair.
@en
Checkpoint mechanisms at the intersection between DNA damage and repair.
@nl
type
label
Checkpoint mechanisms at the intersection between DNA damage and repair.
@en
Checkpoint mechanisms at the intersection between DNA damage and repair.
@nl
prefLabel
Checkpoint mechanisms at the intersection between DNA damage and repair.
@en
Checkpoint mechanisms at the intersection between DNA damage and repair.
@nl
P50
P1433
P1476
Checkpoint mechanisms at the intersection between DNA damage and repair.
@en
P2093
Magda Granata
P304
P356
10.1016/J.DNAREP.2009.04.022
P577
2009-06-03T00:00:00Z