Elevated levels of the polo kinase Cdc5 override the Mec1/ATR checkpoint in budding yeast by acting at different steps of the signaling pathway.
about
Use of quantitative mass spectrometric analysis to elucidate the mechanisms of phospho-priming and auto-activation of the checkpoint kinase Rad53 in vivo.Slx4 and Rtt107 control checkpoint signalling and DNA resection at double-strand breaks.Sae2 promotes DNA damage resistance by removing the Mre11-Rad50-Xrs2 complex from DNA and attenuating Rad53 signaling.The budding yeast Polo-like kinase localizes to distinct populations at centrosomes during mitosis.Regulatory functional territory of PLK-1 and their substrates beyond mitosis.A novel checkpoint and RPA inhibitory pathway regulated by Rif1Polo-like kinase 3 regulates CtIP during DNA double-strand break repair in G1.Pathway profiling and rational trial design for studies in advanced stage cervical carcinoma: a review and a perspective.Functional interplay between the 53BP1-ortholog Rad9 and the Mre11 complex regulates resection, end-tethering and repair of a double-strand break.Hsp90 inhibitors and drug resistance in cancer: the potential benefits of combination therapies of Hsp90 inhibitors and other anti-cancer drugsAnalysis of the ways and methods of signaling pathways in regulating cell cycle of NIH3T3 at transcriptional levelWee1 is required to sustain ATR/Chk1 signaling upon replicative stress.RPA Stabilization of Single-Stranded DNA Is Critical for Break-Induced Replication.Rad53 downregulates mitotic gene transcription by inhibiting the transcriptional activator Ndd1.Eukaryotic DNA damage checkpoint activation in response to double-strand breaks.When genome integrity and cell cycle decisions collide: roles of polo kinases in cellular adaptation to DNA damage.The budding yeast polo-like kinase Cdc5 regulates the Ndt80 branch of the meiotic recombination checkpoint pathway.ATM/Wip1 activities at chromatin control Plk1 re-activation to determine G2 checkpoint duration.Comparative phosphoproteomic analysis of checkpoint recovery identifies new regulators of the DNA damage response.Reduced kinase activity of polo kinase Cdc5 affects chromosome stability and DNA damage response in S. cerevisiae.Tid1/Rdh54 translocase is phosphorylated through a Mec1- and Rad53-dependent manner in the presence of DSB lesions in budding yeast.The RSC chromatin-remodeling complex influences mitotic exit and adaptation to the spindle assembly checkpoint by controlling the Cdc14 phosphatase.Replication checkpoint: tuning and coordination of replication forks in s phase.To trim or not to trim: progression and control of DSB end resectionFunctions and regulation of the Polo-like kinase Cdc5 in the absence and presence of DNA damage.
P2860
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P2860
Elevated levels of the polo kinase Cdc5 override the Mec1/ATR checkpoint in budding yeast by acting at different steps of the signaling pathway.
description
2010 nî lūn-bûn
@nan
2010 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Elevated levels of the polo ki ...... teps of the signaling pathway.
@ast
Elevated levels of the polo ki ...... teps of the signaling pathway.
@en
Elevated levels of the polo ki ...... teps of the signaling pathway.
@nl
type
label
Elevated levels of the polo ki ...... teps of the signaling pathway.
@ast
Elevated levels of the polo ki ...... teps of the signaling pathway.
@en
Elevated levels of the polo ki ...... teps of the signaling pathway.
@nl
prefLabel
Elevated levels of the polo ki ...... teps of the signaling pathway.
@ast
Elevated levels of the polo ki ...... teps of the signaling pathway.
@en
Elevated levels of the polo ki ...... teps of the signaling pathway.
@nl
P2093
P2860
P50
P1433
P1476
Elevated levels of the polo ki ...... teps of the signaling pathway.
@en
P2093
Benjamin Tamilselvan Nachimuthu
Matteo Ferrari
Michela Clerici
Roberto Antonio Donnianni
P2860
P304
P356
10.1371/JOURNAL.PGEN.1000763
P577
2010-01-22T00:00:00Z