Identification of eukaryotic peptide deformylases reveals universality of N-terminal protein processing mechanisms - Wikidata - awgldk - TriplyDB

Identification of eukaryotic peptide deformylases reveals universality of N-terminal protein processing mechanisms

Identification of eukaryotic peptide deformylases reveals universality of N-terminal protein processing mechanisms

http://www.wikidata.org/entity/Q24597763

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Identification and analysis of the acetylated status of poplar proteins reveals analogous N-terminal protein processing mechanisms with other eukaryotes An unusual peptide deformylase features in the human mitochondrial N-terminal methionine excision pathway Human mitochondrial peptide deformylase, a new anticancer target of actinonin-based antibiotics The metalloendopeptidase nardilysin (NRDc) is potently inhibited by heparin-binding epidermal growth factor-like growth factor (HB-EGF)The two authentic methionine aminopeptidase genes are differentially expressed in Bacillus subtilis.N-terminal modifications of cellular proteins: The enzymes involved, their substrate specificities and biological effects Trapping conformational states along ligand-binding dynamics of peptide deformylase: the impact of induced fit on enzyme catalysis Structural variation and inhibitor binding in polypeptide deformylase from four different bacterial species Structure and Activity of Human Mitochondrial Peptide Deformylase, a Novel Cancer Target Understanding the highly efficient catalysis of prokaryotic peptide deformylases by shedding light on the determinants specifying the low activity of the human counterpart Yeast methionine aminopeptidase type 1 is ribosome-associated and requires its N-terminal zinc finger domain for normal function in vivo.Eukaryotic peptide deformylases. Nuclear-encoded and chloroplast-targeted enzymes in Arabidopsis Sorting signals, N-terminal modifications and abundance of the chloroplast proteome The biological functions of Naa10 - From amino-terminal acetylation to human disease Generation of Artificial N-end Rule Substrate Proteins In Vivo and In Vitro.High-throughput identification of inhibitors of human mitochondrial peptide deformylase.N-myristoylation regulates the SnRK1 pathway in Arabidopsis.Target of rapamycin regulates development and ribosomal RNA expression through kinase domain in Arabidopsis.System for expression of microsporidian methionine amino peptidase type 2 (MetAP2) in the yeast Saccharomyces cerevisiae Cell and plastid division are coordinated through the prereplication factor AtCDT1 Ligand-induced changes in the structure and dynamics of Escherichia coli peptide deformylase Megadalton complexes in the chloroplast stroma of Arabidopsis thaliana characterized by size exclusion chromatography, mass spectrometry, and hierarchical clustering Methionine aminopeptidase 2 is a new target for the metastasis-associated protein, S100A4.Expression of Escherichia coli methionyl-tRNA formyltransferase in Saccharomyces cerevisiae leads to formylation of the cytoplasmic initiator tRNA and possibly to initiation of protein synthesis with formylmethionine.Identification of protein stability determinants in chloroplasts Exploration of the core metabolism of symbiotic bacteria.Peptide deformylase: a target for novel antibiotics?Control of protein life-span by N-terminal methionine excision The crystal structure of mitochondrial (Type 1A) peptide deformylase provides clear guidelines for the design of inhibitors specific for the bacterial forms.Impact of the N-terminal amino acid on targeted protein degradation.Overexpression of peptide deformylase in breast, colon, and lung cancers.Identification of crucial amino acids of bacterial Peptide deformylases affecting enzymatic activity in response to oxidative stress Novel agents for the treatment of resistant Gram-positive infections.Peptide deformylase inhibitors as potent antimycobacterial agents.An N-terminal formyl methionine on COX 1 is required for the assembly of cytochrome c oxidase.Genome-wide identification and in silico analysis of poplar peptide deformylases.Structure-Based Drug Design of Small Molecule Peptide Deformylase Inhibitors to Treat Cancer.The plastid-derived organelle of protozoan human parasites as a target of established and emerging drugs.Zinc is the metal cofactor of Borrelia burgdorferi peptide deformylase.Delineation of alternative conformational states in Escherichia coli peptide deformylase via thermodynamic studies for the binding of actinonin.

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P2860

Identification of eukaryotic peptide deformylases reveals universality of N-terminal protein processing mechanisms

http://www.wikidata.org/entity/Q24597763

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2000 nî lūn-bûn

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2000 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

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Identification of eukaryotic p ...... protein processing mechanisms

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Identification of eukaryotic p ...... protein processing mechanisms

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Identification of eukaryotic p ...... protein processing mechanisms

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Identification of eukaryotic p ...... protein processing mechanisms

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Identification of eukaryotic p ...... protein processing mechanisms

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A Serero

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P2860

A Gene Map of the Human Genome

Eukaryotic methionyl aminopeptidases: two classes of cobalt-dependent enzymes

Removal of a cryptic intron and subcellular localization of green fluorescent protein are required to mark transgenic Arabidopsis plants brightly

Genetic characterization of polypeptide deformylase, a distinctive enzyme of eubacterial translation

The N-end rule: functions, mysteries, uses

The anti-angiogenic agent fumagillin covalently binds and inhibits the methionine aminopeptidase, MetAP-2

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

Basic local alignment search tool

Escherichia coli methionine aminopeptidase: implications of crystallographic analyses of the native, mutant, and inhibited enzymes for the mechanism of catalysis

Crystal structure of methionine aminopeptidase from hyperthermophile, Pyrococcus furiosus

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