Sequence-specific photo-induced cross-linking of the two strands of double-helical DNA by a psoralen covalently linked to a triple helix-forming oligonucleotide.
about
Triplex targeted genomic crosslinks enter separable deletion and base substitution pathwaysTargeted correction of an episomal gene in mammalian cells by a short DNA fragment tethered to a triplex-forming oligonucleotide.Padlock oligonucleotides as a tool for labeling superhelical DNA.Site-directed recombination via bifunctional PNA-DNA conjugates.Psoralen interstrand cross-link repair is specifically altered by an adjacent triple-stranded structureControl of gene expression by triple helix-forming oligonucleotides. The antigene strategy.Methods for the large-scale synthesis of psoralen furan-side monoadducts and diadductsReversible photocycloaddition of a 4',5'-dihydropsoralen derivative with thymine.Oligodeoxynucleotide-directed photo-induced cross-linking of HIV proviral DNA via triple-helix formation.Specific inhibition of transcription by triple helix-forming oligonucleotidesHuman MLH1 protein participates in genomic damage checkpoint signaling in response to DNA interstrand crosslinks, while MSH2 functions in DNA repairPeptide conjugates for chromosomal gene targeting by triplex-forming oligonucleotidesTargeting and processing of site-specific DNA interstrand crosslinks.A molecular anchor for stabilizing triple-helical DNA.Polymorphic nucleic Acid binding of bioactive isoquinoline alkaloids and their role in cancer.Photoswitchable formation of a DNA interstrand cross-link by a coumarin-modified nucleotide.Triplex technology in studies of DNA damage, DNA repair, and mutagenesisDNA binding and antigene activity of a daunomycin-conjugated triplex-forming oligonucleotide targeting the P2 promoter of the human c-myc gene.Rapid and efficient hybridization-triggered crosslinking within a DNA duplex by an oligodeoxyribonucleotide bearing a conjugated cyclopropapyrroloindole.Triplex formation by a psoralen-conjugated oligodeoxyribonucleotide containing the base analog 8-oxo-adenine.Effect of third strand composition on the triple helix formation: purine versus pyrimidine oligodeoxynucleotidesDetection of covalent triplex within human cellsExtension of the range of DNA sequences available for triple helix formation: stabilization of mismatched triplexes by acridine-containing oligonucleotides.Fluorescence energy transfer as a probe for nucleic acid structures and sequences.Site-specific targeting of psoralen photoadducts with a triple helix-forming oligonucleotide: characterization of psoralen monoadduct and crosslink formation.Sequence specific inhibition of DNA restriction enzyme cleavage by PNA.In vivo transcription of a progesterone-responsive gene is specifically inhibited by a triplex-forming oligonucleotideUnambiguous demonstration of triple-helix-directed gene modification.Repairing the Sickle Cell mutation. III. Effect of irradiation wavelength on the specificity and type of photoproduct formed by a 3'-terminal psoralen on a third strand directed to the mutant base pair.Universal strategies for the DNA-encoding of libraries of small molecules using the chemical ligation of oligonucleotide tags.Recognition of triple-helical DNA structures by transposon Tn7.Accessibility of nuclear DNA to triplex-forming oligonucleotides: the integrated HIV-1 provirus as a targetA simple, high-yield synthesis of DNA duplexes containing a covalent, thermally cleavable interstrand cross-link at a defined locationDNA damage-dependent transcriptional arrest and termination of RNA polymerase II elongation complexes in DNA template containing HIV-1 promoter.Inhibition of gene expression by triple helix-directed DNA cross-linking at specific sites.Targeted mutagenesis of DNA using triple helix-forming oligonucleotides linked to psoralen.Targeted mutagenesis in mammalian cells mediated by intracellular triple helix formation.Oligonucleotide clamps arrest DNA synthesis on a single-stranded DNA target.Targeted mutagenesis of simian virus 40 DNA mediated by a triple helix-forming oligonucleotideThe triple helix: 50 years later, the outcome.
P2860
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P2860
Sequence-specific photo-induced cross-linking of the two strands of double-helical DNA by a psoralen covalently linked to a triple helix-forming oligonucleotide.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on July 1991
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Sequence-specific photo-induce ...... helix-forming oligonucleotide.
@en
Sequence-specific photo-induce ...... helix-forming oligonucleotide.
@nl
type
label
Sequence-specific photo-induce ...... helix-forming oligonucleotide.
@en
Sequence-specific photo-induce ...... helix-forming oligonucleotide.
@nl
prefLabel
Sequence-specific photo-induce ...... helix-forming oligonucleotide.
@en
Sequence-specific photo-induce ...... helix-forming oligonucleotide.
@nl
P2093
P2860
P356
P1476
Sequence-specific photo-induce ...... helix-forming oligonucleotide.
@en
P2093
Chassignol M
Guendouz A
Takasugi M
P2860
P304
P356
10.1073/PNAS.88.13.5602
P407
P577
1991-07-01T00:00:00Z