Mechanical motion promotes expression of Prg4 in articular cartilage via multiple CREB-dependent, fluid flow shear stress-induced signaling pathways.
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The autocrine role of proteoglycan-4 (PRG4) in modulating osteoarthritic synoviocyte proliferation and expression of matrix degrading enzymes.Friction-Induced Mitochondrial Dysregulation Contributes to Joint Deterioration in Prg4 Knockout Mice.The mechanobiology of articular cartilage: bearing the burden of osteoarthritis.Integrin αv in the mechanical response of osteoblast lineage cells.Biomechanical forces promote blood development through prostaglandin E2 and the cAMP-PKA signaling axis.Flow-induced protein kinase A-CREB pathway acts via BMP signaling to promote HSC emergence.Early postnatal ablation of the microRNA-processing enzyme, Drosha, causes chondrocyte death and impairs the structural integrity of the articular cartilage.Cartilage Derived from Bone Marrow Mesenchymal Stem Cells Expresses Lubricin In Vitro and In Vivo.Messenger RNA delivery of a cartilage-anabolic transcription factor as a disease-modifying strategy for osteoarthritis treatment.Deletion of Panx3 Prevents the Development of Surgically Induced OsteoarthritisPterosin B prevents chondrocyte hypertrophy and osteoarthritis in mice by inhibiting Sik3.Stem Cells in Skeletal Tissue Engineering: Technologies and Models.Co-Expression and Co-Localization of Cartilage Glycoproteins CHI3L1 and Lubricin in Osteoarthritic Cartilage: Morphological, Immunohistochemical and Gene Expression ProfilesBuilding and maintaining joints by exquisite local control of cell fate.Signaling networks in joint development.Meniscus, articular cartilage and nucleus pulposus: a comparative review of cartilage-like tissues in anatomy, development and function.Identification of a Prg4-expressing articular cartilage progenitor cell population in mice.Hyperbaric oxygen protects type II collagen in interleukin-1β-induced mandibular condylar chondrocyte via inhibiting the JNK/c-Jun signaling pathway.Physical activity ameliorates cartilage degeneration in a rat model of aging: a study on lubricin expression.Cartilage-specific deletion of Alk5 gene results in a progressive osteoarthritis-like phenotype in mice.Acoustically modulated biomechanical stimulation for human cartilage tissue engineering.Definition of a Critical Size Osteochondral Knee Defect and its Negative Effect on the Surrounding Articular Cartilage in the Rat.Role of follistatin in muscle and bone alterations induced by gravity change in mice.Superficial cells are self-renewing chondrocyte progenitors, which form the articular cartilage in juvenile mice.Tissue Force Programs Cell Fate and Tumor Aggression.Association of lubricin concentration in synovial fluid and clinical status of osteoarthritic knee.Different Chondrogenic Potential among Human Induced Pluripotent Stem Cells from Diverse Origin Primary Cells.Biofabrication of in situ Self Assembled 3D Cell Cultures in a Weightlessness Environment Generated using Magnetic Levitation.Repair of Damaged Articular Cartilage: Current Approaches and Future DirectionsThe Resting Potential and K Currents in Primary Human Articular Chondrocytes
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Mechanical motion promotes expression of Prg4 in articular cartilage via multiple CREB-dependent, fluid flow shear stress-induced signaling pathways.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on January 2014
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Mechanical motion promotes exp ...... ss-induced signaling pathways.
@en
Mechanical motion promotes exp ...... ss-induced signaling pathways.
@nl
type
label
Mechanical motion promotes exp ...... ss-induced signaling pathways.
@en
Mechanical motion promotes exp ...... ss-induced signaling pathways.
@nl
prefLabel
Mechanical motion promotes exp ...... ss-induced signaling pathways.
@en
Mechanical motion promotes exp ...... ss-induced signaling pathways.
@nl
P2093
P2860
P356
P1433
P1476
Mechanical motion promotes exp ...... ss-induced signaling pathways.
@en
P2093
Alan J Grodzinsky
Andrew B Lassar
Elena Kozhemyakina
Han-Hwa Hung
Hiroyasu Ogawa
P2860
P304
P356
10.1101/GAD.231969.113
P577
2014-01-01T00:00:00Z