Activators of protein kinase C down-regulate and phosphorylate the T3/T-cell antigen receptor complex of human T lymphocytes.
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The CD4 and CD8 antigens are coupled to a protein-tyrosine kinase (p56lck) that phosphorylates the CD3 complexPrimary structure of the T3 gamma subunit of the T3/T cell antigen receptor complex deduced from cDNA sequences: evolution of the T3 gamma and delta subunitsHuman type II Fcgamma receptors inhibit B cell activation by interacting with the p21(ras)-dependent pathwayIdentity of the elusive IgM Fc receptor (FcmuR) in humans.Activation of human T lymphocytes: differential effects of CD3- and CD8-mediated signals.Human immunodeficiency virus type 2 produces a defect in CD3-gamma gene transcripts similar to that observed for human immunodeficiency virus type 1.Exogenous ATP and other nucleoside phosphates modulate epidermal growth factor receptors of A-431 epidermoid carcinoma cells.Early events of human T lymphocyte activation are associated with type I protein kinase A activity.Immunomodulatory effects of therapeutic gold compounds. Gold sodium thiomalate inhibits the activity of T cell protein kinase C.Isolation and characterization of a T-lymphocyte somatic mutant with altered signal transduction by the antigen receptor.Expression of the human B-cell surface protein CD20: alteration by phorbol 12-myristate 13-acetate.Biosynthesis, glycosylation, and partial N-terminal amino acid sequence of the T-cell-activating protein TAP.T3 glycoprotein is functional although structurally distinct on human T-cell receptor gamma T lymphocytesModulation of the human T cell response by a novel non-mitogenic anti-CD3 antibodyAdhesion molecules of cultured hematopoietic malignancies. A calcium-dependent lectin is the principle mediator of binding to the high endothelial venule of lymph nodes.Multiformat T-cell-engaging bispecific antibodies targeting human breast cancers.Protein kinase C and beyond.Endocytosis and recycling of the T3-T cell receptor complex. The role of T3 phosphorylation.Cloning and sequencing of murine T3 gamma cDNA from a subtractive cDNA library.Postnatal disappearance of self-reactive (V beta 6+) cells from the thymus of Mlsa mice. Implications for T cell development and autoimmunity.Dissociation of intracellular signaling pathways in response to partial agonist ligands of the T cell receptor.Calcium-dependent immediate-early gene induction in lymphocytes is negatively regulated by p21Ha-rasCD22-mediated stimulation of T cells regulates T-cell receptor/CD3-induced signaling.Downregulation of T cell receptor expression by CD8(+) lymphocytes in kidney allograftsIntracytoplasmic phosphorylation sites of Tac antigen (p55) are not essential for the conformation, function, and regulation of the human interleukin 2 receptor.Transient alteration of T cell fine specificity by a strong primary stimulus correlates with T cell receptor down-regulation.The immunological synapse: a focal point for endocytosis and exocytosis.Structure and function of the T cell antigen receptor.Serine-threonine kinases in TCR signaling.High expression of CD26 accurately identifies human bacteria-reactive MR1-restricted MAIT cells.12-0-Tetradecanoyl Phorbol-13-Acetate (TPA) and Its Effect on Leukaemic Cells, In-vitro-A Review.The T-cell antigen receptor. Structure and mechanism of activation.Generation and analysis of a T-lymphocyte somatic mutant for studying molecular aspects of signal transduction by the antigen receptor.Oncogenic K-RAS subverts the antiapoptotic role of N-RAS and alters modulation of the N-RAS:gelsolin complex.Masking of the CD3 gamma di-leucine-based motif by zeta is required for efficient T-cell receptor expression.Role of protein kinase C in T-cell antigen receptor regulation of p21ras: evidence that two p21ras regulatory pathways coexist in T cellsSignal transduction in primary human T lymphocytes in altered gravity - results of the MASER-12 suborbital space flight mission.CD3 gamma contains a phosphoserine-dependent di-leucine motif involved in down-regulation of the T cell receptor.Antigen-induced TCR-CD3 down-modulation does not require CD3delta or CD3gamma cytoplasmic domains, necessary in response to anti-CD3 antibody.Molecular characterization of the di-leucine-based internalization motif of the T cell receptor.
P2860
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P2860
Activators of protein kinase C down-regulate and phosphorylate the T3/T-cell antigen receptor complex of human T lymphocytes.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on December 1985
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Activators of protein kinase C ...... omplex of human T lymphocytes.
@en
Activators of protein kinase C ...... omplex of human T lymphocytes.
@nl
type
label
Activators of protein kinase C ...... omplex of human T lymphocytes.
@en
Activators of protein kinase C ...... omplex of human T lymphocytes.
@nl
prefLabel
Activators of protein kinase C ...... omplex of human T lymphocytes.
@en
Activators of protein kinase C ...... omplex of human T lymphocytes.
@nl
P2093
P2860
P356
P1476
Activators of protein kinase C ...... omplex of human T lymphocytes.
@en
P2093
Cantrell DA
Crumpton MJ
P2860
P304
P356
10.1073/PNAS.82.23.8158
P407
P577
1985-12-01T00:00:00Z