Isolation and characterization of a T-lymphocyte somatic mutant with altered signal transduction by the antigen receptor.
about
P1343
Phosphoprotein associated with glycosphingolipid-enriched microdomains (PAG), a novel ubiquitously expressed transmembrane adaptor protein, binds the protein tyrosine kinase csk and is involved in regulation of T cell activationThe kinase, SH3, and SH2 domains of Lck play critical roles in T-cell activation after ZAP-70 membrane localizationCo-localization of HIV-1 Nef with the AP-2 adaptor protein complex correlates with Nef-induced CD4 down-regulationL-selectin activates the Ras pathway via the tyrosine kinase p56lckSignaling advances from immunogenetics to immunogenomicsAurora A drives early signalling and vesicle dynamics during T-cell activation.Cytokine-independent Jak3 activation upon T cell receptor (TCR) stimulation through direct association of Jak3 and the TCR complexLAT, the linker for activation of T cells: a bridge between T cell-specific and general signaling pathwaysT cell Ig and mucin domain-1-mediated T cell activation requires recruitment and activation of phosphoinositide 3-kinaseHerpes simplex virus requires VP11/12 to induce phosphorylation of the activation loop tyrosine (Y394) of the Src family kinase Lck in T lymphocytes.The lck SH3 domain is required for activation of the mitogen-activated protein kinase pathway but not the initiation of T-cell antigen receptor signaling.Identification of gene function by cyclical packaging rescue of retroviral cDNA libraries.Zeta chain of the T-cell receptor interacts with nef of simian immunodeficiency virus and human immunodeficiency virus type 2At least two non-antigen-binding molecules are required for signal transduction by the T-cell antigen receptor.Genetic evidence for differential coupling of Syk family kinases to the T-cell receptor: reconstitution studies in a ZAP-70-deficient Jurkat T-cell line.Genetic evidence of a role for Lck in T-cell receptor function independent or downstream of ZAP-70/Syk protein tyrosine kinases.Vav-Rac1-mediated activation of the c-Jun N-terminal kinase/c-Jun/AP-1 pathway plays a major role in stimulation of the distal NFAT site in the interleukin-2 gene promoterBasal LAT-diacylglycerol-RasGRP1 signals in T cells maintain TCRα gene expressionLigand-induced association between the T-cell antigen receptor and two glycoproteins.Modulation of T-cell receptor signal transduction by herpesvirus signaling adaptor protein.Integrin-mediated tyrosine phosphorylation of Shc in T cells is regulated by protein kinase C-dependent phosphorylations of LckCooperative interactions of simian immunodeficiency virus Nef, AP-2, and CD3-zeta mediate the selective induction of T-cell receptor-CD3 endocytosis.The Syk protein tyrosine kinase can function independently of CD45 or Lck in T cell antigen receptor signalingA CRISPR-Based Toolbox for Studying T Cell Signal Transduction.Regions of the T cell receptor alpha and beta chains that are responsible for interactions with CD3.Functional characterization of a signal transducing motif present in the T cell antigen receptor zeta chain.T cell receptor engagement leads to phosphorylation of clathrin heavy chain during receptor internalization.The SH3 domain of Lck modulates T-cell receptor-dependent activation of extracellular signal-regulated kinase through activation of Raf-1.A functional T-cell receptor signaling pathway is required for p95vav activity.Cell-type-specific tyrosine phosphorylation of the herpes simplex virus tegument protein VP11/12 encoded by gene UL46.Defective expression of p56lck in an infant with severe combined immunodeficiency.Functional activation of the T-cell antigen receptor induces tyrosine phosphorylation of phospholipase C-gamma 1.The right team at the right time to go for a home run: tyrosine kinase activation by the TCR.Structure and function of the T cell antigen receptor.The role of membrane rafts in Lck transport, regulation and signalling in T-cells.Redox regulation of T-cell receptor signaling.2B4 utilizes ITAM-containing receptor complexes to initiate intracellular signaling and cytolysis.Generation and analysis of a T-lymphocyte somatic mutant for studying molecular aspects of signal transduction by the antigen receptor.Src-like adaptor protein down-regulates T cell receptor (TCR)-CD3 expression by targeting TCRzeta for degradation.Identification of cells deficient in signaling-induced alternative splicing by use of somatic cell genetics.
P2860
Q22254014-9648659C-1744-4D60-8CCD-8811333E27F5Q24324202-FEA7CDB7-DB20-422C-8219-870B91B978C2Q24532862-5C8E1C4A-B03D-47A4-8FD1-3DF033C1CC30Q24653696-BCA38E11-2B17-4852-81F0-7F72494C36A1Q24793529-3265A5AF-C2C8-4800-9C27-D0762653BA6CQ27318948-7532CFFC-596E-4F63-AA83-4257C5952A49Q28188446-C30E317F-1DBB-4794-8797-4BAD50085EAEQ28213042-E2CA31BB-E71A-4497-A7E1-69CD15AACD62Q28755503-3DA3CB46-6514-4527-B122-DAE874ED9C0EQ30157107-3A9DDDEA-F6C3-4050-82F1-65959368A466Q30175876-54E4FC82-BB89-4D3B-B274-D7838B41D1C3Q31088303-0E7A46A9-E0F8-4A16-8A8B-09089CA69E74Q31976743-42FB602D-B56E-4893-A304-406248CFD875Q33671547-B805EADF-CBFA-4C8A-8988-B8AC516E4F3FQ33772316-316B09AE-3768-4BC1-AFFB-5A32E2D8E6F5Q33786556-2A0A4E30-6640-43D2-97E7-FA53EAB54421Q33968015-8AD7C7F6-9736-4592-809C-3DBA7E6325C2Q34038396-C70A6E67-D256-4298-93F8-79D1D0BAD70DQ34304264-02C2BD84-5DDE-4C72-8119-A0F3F7DD7E7DQ34347767-9A071816-3224-46FE-BB89-2C892A9D9DADQ34763949-9A1B42C7-3971-42CA-93A0-440BE13E0C03Q35105271-5852B35E-0B58-4304-AEF0-3163C3467989Q35914986-54E00FB5-ABD0-4C52-B6CB-DE6ECD178FE5Q35983356-C0E36DBB-1B7D-4013-A2C3-36BD60114DF8Q36230059-E4F7E65C-4F2B-4770-8A91-5A6703BA5A63Q36361637-0BCFCD8B-3B3B-46E3-90FB-2A26EF7D0254Q36399415-150C463F-23D0-4999-8A16-47E0E5081646Q36421433-7F4D315A-AACC-43B7-AD6F-915400A29DB8Q36553748-1E99E055-574B-468A-873E-62A96F3E0CFAQ36747946-18A17610-2BC6-4A49-B9A7-D193BAC468E7Q37383981-CC628DF4-B056-4465-8E4D-6B04A108A40EQ37536882-6486F668-B269-4509-A895-1565BF6FB2C6Q37677539-2BC222D1-2884-47A9-B912-A90BC8666E14Q37961459-DDBAFF91-B57A-43F4-842D-4D94AB241312Q38127836-4AD4C5B9-C1D4-4D64-8999-8F1F6190C912Q38381498-B773A77B-DC01-4CC2-BB08-404E675B9602Q39570265-A19C943A-19A2-41CE-8297-DCC8C1FBAD7BQ39574545-FBAE0656-2514-44D6-96A9-0C2C77E7D05FQ40396154-7784B3EC-5475-4BD0-9216-31C80DD1DF47Q40679291-BC21761E-C9AD-4E28-A2A0-B9C523281724
P2860
Isolation and characterization of a T-lymphocyte somatic mutant with altered signal transduction by the antigen receptor.
description
1987 nî lūn-bûn
@nan
1987 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1987 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
1987年の論文
@ja
1987年学术文章
@wuu
1987年学术文章
@zh-cn
1987年学术文章
@zh-hans
1987年学术文章
@zh-my
1987年学术文章
@zh-sg
1987年學術文章
@yue
name
Isolation and characterization ...... ction by the antigen receptor.
@ast
Isolation and characterization ...... ction by the antigen receptor.
@en
Isolation and characterization ...... ction by the antigen receptor.
@nl
type
label
Isolation and characterization ...... ction by the antigen receptor.
@ast
Isolation and characterization ...... ction by the antigen receptor.
@en
Isolation and characterization ...... ction by the antigen receptor.
@nl
prefLabel
Isolation and characterization ...... ction by the antigen receptor.
@ast
Isolation and characterization ...... ction by the antigen receptor.
@en
Isolation and characterization ...... ction by the antigen receptor.
@nl
P2860
P356
P1476
Isolation and characterization ...... ction by the antigen receptor.
@en
P2093
P2860
P304
P356
10.1073/PNAS.84.19.6879
P407
P4510
P577
1987-10-01T00:00:00Z