Critical roles of the S3 segment and S3-S4 linker of repeat I in activation of L-type calcium channels
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Exclusion of defects in the skeletal muscle specific regions of the DHPR alpha 1 subunit as frequent causes of malignant hyperthermiaStructural elements in domain IV that influence biophysical and pharmacological properties of human alpha1A-containing high-voltage-activated calcium channels.Critical Role of Intracellular RyR1 Calcium Release Channels in Skeletal Muscle Function and DiseaseL-type calcium channels: the low downThe S5-S6 linker of repeat I is a critical determinant of L-type Ca2+ channel conductanceGenomic organization and evolution of alternative exons in a Drosophila calcium channel geneCa2+ current activation rate correlates with alpha 1 subunit density.Control of ion conduction in L-type Ca2+ channels by the concerted action of S5-6 regions.Helical secondary structure of the external S3-S4 linker of pacemaker (HCN) channels revealed by site-dependent perturbations of activation phenotype.Control of gating mode by a single amino acid residue in transmembrane segment IS3 of the N-type Ca2+ channel.Pore stability and gating in voltage-activated calcium channelsThe impact of splice isoforms on voltage-gated calcium channel alpha1 subunits.Topology of the Shaker potassium channel probed with hydrophilic epitope insertionsRole of the S4 in cooperativity of voltage-dependent potassium channel activation.Characterization of ether-à-go-go channels present in photoreceptors reveals similarity to IKx, a K+ current in rod inner segmentsUnitary behavior of skeletal, cardiac, and chimeric L-type Ca2+ channels expressed in dysgenic myotubes.Role of the S3-S4 linker in Shaker potassium channel activation.Role of calcium permeation in dihydropyridine receptor function. Insights into channel gating and excitation-contraction coupling.Kv3.1 uses a timely resurgent K(+) current to secure action potential repolarization.Alternative splicing: functional diversity among voltage-gated calcium channels and behavioral consequences.Hair cell-specific splicing of mRNA for the alpha1D subunit of voltage-gated Ca2+ channels in the chicken's cochlea.The α2δ-1 subunit remodels CaV1.2 voltage sensors and allows Ca2+ influx at physiological membrane potentialsA CaV1.1 Ca2+ channel splice variant with high conductance and voltage-sensitivity alters EC coupling in developing skeletal muscle.Linker flexibility of IVS3-S4 loops modulates voltage-dependent activation of L-type Ca2+ channels.How and why are calcium currents curtailed in the skeletal muscle voltage-gated calcium channels?Arrhythmogenic transient dynamics in cardiac myocytes.L-type CaV1.2 calcium channels: from in vitro findings to in vivo function.Alternative splicing in the voltage-sensing region of N-Type CaV2.2 channels modulates channel kinetics.The mammalian skeletal muscle DHPR has larger Ca2+ conductance and is phylogenetically ancient to the early ray-finned fish sterlet (Acipenser ruthenus).Structural and functional modularity of voltage-gated potassium channels.Divergent biophysical properties, gating mechanisms, and possible functions of the two skeletal muscle Ca(V)1.1 calcium channel splice variantsSpecific contributions of the four voltage-sensing domains in L-type calcium channels to gating and modulation.Two distinct voltage-sensing domains control voltage sensitivity and kinetics of current activation in CaV1.1 calcium channels.Identification of a surface charged residue in the S3-S4 linker of the pacemaker (HCN) channel that influences activation gating.External Ca(2+)-dependent excitation--contraction coupling in a population of ageing mouse skeletal muscle fibres.Panulirus interruptus Ih-channel gene PIIH: modification of channel properties by alternative splicing and role in rhythmic activity.Functional roles of the extracellular segments of the sodium channel alpha subunit in voltage-dependent gating and modulation by beta1 subunits.Effects of mutations causing hypokalaemic periodic paralysis on the skeletal muscle L-type Ca2+ channel expressed in Xenopus laevis oocytes.Transfer of L-type calcium channel IVS6 segment increases phenylalkylamine sensitivity of alpha1A.Voltage-dependent inactivation in a cardiac-skeletal chimeric calcium channel.
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Critical roles of the S3 segment and S3-S4 linker of repeat I in activation of L-type calcium channels
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on February 1994
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Critical roles of the S3 segme ...... ion of L-type calcium channels
@en
Critical roles of the S3 segme ...... on of L-type calcium channels.
@nl
type
label
Critical roles of the S3 segme ...... ion of L-type calcium channels
@en
Critical roles of the S3 segme ...... on of L-type calcium channels.
@nl
prefLabel
Critical roles of the S3 segme ...... ion of L-type calcium channels
@en
Critical roles of the S3 segme ...... on of L-type calcium channels.
@nl
P2093
P2860
P356
P1476
Critical roles of the S3 segme ...... ion of L-type calcium channels
@en
P2093
P2860
P304
P356
10.1073/PNAS.91.3.1014
P407
P577
1994-02-01T00:00:00Z