The carbohydrate domain of calicheamicin gamma I1 determines its sequence specificity for DNA cleavage.
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Cleavage behavior of calicheamicin gamma 1 and calicheamicin TChemistry and biology of natural and designed enediynesThe DNA-damage signature in Saccharomyces cerevisiae is associated with single-strand breaks in DNA.Calicheamicin-DNA complexes: warhead alignment and saccharide recognition of the minor groove.The cytotoxicity of (-)-lomaiviticin A arises from induction of double-strand breaks in DNA.Interaction of calicheamicin gamma1(I) and its related carbohydrates with DNA-protein complexes.Crystal structure of O-methyltransferase CalO6 from the calicheamicin biosynthetic pathway: a case of challenging structure determination at low resolution.Organic synthesis and cell biology: partners in controlling gene expression.Specific inhibition of formation of transcription complexes by a calicheamicin oligosaccharide: a paradigm for the development of transcriptional antagonists.Kedarcidin chromophore: an enediyne that cleaves DNA in a sequence-specific manner.Simultaneous determination of helical unwinding angles and intrinsic association constants in ligand-DNA complexes: the interaction between DNA and calichearubicin B.Intervention of carbohydrate recognition by proteins and nucleic acids.Probing the biology of natural products: molecular editing by diverted total synthesis.Natural glycoconjugates with antitumor activity.Structural and conformational features relevant to the anti-tumor activity of calicheamicin γ 1I.Heteroatom-Heteroatom Bond Formation in Natural Product Biosynthesis.Designed enediynes: a new class of DNA-cleaving molecules with potent and selective anticancer activity.Novel insights on the DNA interaction of calicheamicin γ1I
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The carbohydrate domain of calicheamicin gamma I1 determines its sequence specificity for DNA cleavage.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on September 1991
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
The carbohydrate domain of cal ...... specificity for DNA cleavage.
@en
The carbohydrate domain of cal ...... specificity for DNA cleavage.
@nl
type
label
The carbohydrate domain of cal ...... specificity for DNA cleavage.
@en
The carbohydrate domain of cal ...... specificity for DNA cleavage.
@nl
prefLabel
The carbohydrate domain of cal ...... specificity for DNA cleavage.
@en
The carbohydrate domain of cal ...... specificity for DNA cleavage.
@nl
P2093
P2860
P356
P1476
The carbohydrate domain of cal ...... specificity for DNA cleavage.
@en
P2093
D M Crothers
S Danishefsky
P2860
P304
P356
10.1073/PNAS.88.17.7464
P407
P577
1991-09-01T00:00:00Z