Tumour suppression by p53: a role for the DNA damage response?
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Vaccinia-related kinase 1 (VRK1) is an upstream nucleosomal kinase required for the assembly of 53BP1 foci in response to ionizing radiation-induced DNA damageSOX11 expression correlates to promoter methylation and regulates tumor growth in hematopoietic malignanciesMultiple facets of p53 in senescence induction and maintenanceChemical Variations on the p53 Reactivation ThemeNoncoding RNAs in DNA repair and genome integrityPARP Inhibitors for BRCA1/2 mutation-associated and BRCA-like malignanciesAtomic Structure of Dual-Specificity Phosphatase 26, a Novel p53 PhosphataseStructural basis of how stress-induced MDMX phosphorylation activates p53The Double Role of p53 in Cancer and Autoimmunity and Its Potential as Therapeutic TargetFOXM1 in sarcoma: role in cell cycle, pluripotency genes and stem cell pathwaysRegulatory Roles of Rpl22 in Hematopoiesis: An Old Dog with New TricksRNF144A, an E3 ubiquitin ligase for DNA-PKcs, promotes apoptosis during DNA damageComparison of toxicogenomics and traditional approaches to inform mode of action and points of departure in human health risk assessment of benzo[a]pyrene in drinking watermRNA Display Selection of an Optimized MDM2-Binding Peptide That Potently Inhibits MDM2-p53 InteractionTriptolide induces growth inhibition and apoptosis of human laryngocarcinoma cells by enhancing p53 activities and suppressing E6-mediated p53 degradationHexavalent chromium-induced apoptosis of granulosa cells involves selective sub-cellular translocation of Bcl-2 members, ERK1/2 and p53SUMO-specific protease 2 in Mdm2-mediated regulation of p53The E3 Ligase CHIP Mediates p21 Degradation to Maintain Radioresistance.The yin-yang of DNA damage response: roles in tumorigenesis and cellular senescence.Akt3 is responsible for the survival and proliferation of embryonic stem cellsSelf-Renewal Signalling in Presenescent Tetraploid IMR90 Cells.p53-mediated activation of the mitochondrial protease HtrA2/Omi prevents cell invasion.Variations in dysfunction of sister chromatid cohesion in esco2 mutant zebrafish reflect the phenotypic diversity of Roberts syndromeIrradiation selects for p53-deficient hematopoietic progenitors.miR-365 promotes cutaneous squamous cell carcinoma (CSCC) through targeting nuclear factor I/B (NFIB)A team of heterochromatin factors collaborates with small RNA pathways to combat repetitive elements and germline stress.Suppression of Akt-mTOR pathway-a novel component of oncogene induced DNA damage response barrier in breast tumorigenesisSharp-1 modulates the cellular response to DNA damage.Histone methyltransferase SETDB1 regulates liver cancer cell growth through methylation of p53Alterations of tumor-related genes do not exactly match the histopathological grade in gastric adenocarcinomas.{Delta}Np73{beta} puts the brakes on DNA repair.The cancer theory of pulmonary arterial hypertension.Mutant TP53 posttranslational modifications: challenges and opportunities.The effects of fucodian on senescence are controlled by the p16INK4a-pRb and p14Arf-p53 pathways in hepatocellular carcinoma and hepatic cell lines.Rnf8 deficiency impairs class switch recombination, spermatogenesis, and genomic integrity and predisposes for cancer.Predictors of recurrence in breast cancer subtypes with negative lymph node in a Chinese population.Posttranslational modification of p53: cooperative integrators of functionClassical and Novel Prognostic Markers for Breast Cancer and their Clinical Significance.NSC109268 potentiates cisplatin-induced cell death in a p53-independent manner.p53 loss promotes acute myeloid leukemia by enabling aberrant self-renewal.
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Tumour suppression by p53: a role for the DNA damage response?
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 04 September 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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Tumour suppression by p53: a role for the DNA damage response?
@en
Tumour suppression by p53: a role for the DNA damage response?
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type
label
Tumour suppression by p53: a role for the DNA damage response?
@en
Tumour suppression by p53: a role for the DNA damage response?
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prefLabel
Tumour suppression by p53: a role for the DNA damage response?
@en
Tumour suppression by p53: a role for the DNA damage response?
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P2860
P356
P1476
Tumour suppression by p53: a role for the DNA damage response?
@en
P2093
David W Meek
P2860
P2888
P304
P356
10.1038/NRC2716
P407
P577
2009-09-04T00:00:00Z