p21 activated kinase signaling coordinates glycoprotein receptor VI-mediated platelet aggregation, lamellipodia formation, and aggregate stability under shear.
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p21-Activated kinase (PAK) regulates cytoskeletal reorganization and directional migration in human neutrophilsLysine acetyltransfer supports platelet function.Pak2 restrains endomitosis during megakaryopoiesis and alters cytoskeleton organization.P21-activated kinase in inflammatory and cardiovascular disease.The BCR-ABL inhibitor ponatinib inhibits platelet immunoreceptor tyrosine-based activation motif (ITAM) signaling, platelet activation and aggregate formation under shear.Gq-mediated Akt translocation to the membrane: a novel PIP3-independent mechanism in platelets.Scoparone interferes with STAT3-induced proliferation of vascular smooth muscle cells.RhoA and Rac1 GTPases Differentially Regulate Agonist-Receptor Mediated Reactive Oxygen Species Generation in PlateletsRho-GTPase and Atherosclerosis: Pleiotropic Effects of StatinsHeat shock protein 70 regulates platelet integrin activation, granule secretion and aggregation.The p21-activated kinase, PAK2, is important in the activation of numerous pancreatic acinar cell signaling cascades and in the onset of early pancreatitis eventsThe PAK system links Rho GTPase signaling to thrombin-mediated platelet activationOral administration of Bruton's tyrosine kinase inhibitors impairs GPVI-mediated platelet function.Histone deacetylase 6-mediated deacetylation of α-tubulin coordinates cytoskeletal and signaling events during platelet activation.Cdc42-dependent F-actin dynamics drive structuration of the demarcation membrane system in megakaryocytes.Assessment of roles for the Rho-specific guanine nucleotide dissociation inhibitor Ly-GDI in platelet function: a spatial systems approach.Platelet procoagulant phenotype is modulated by a p38 - MK2 axis regulating RTN4/Nogo proximal to the endoplasmic reticulum: utility of pathway analysis.Potentiation of TRAP-6-induced platelet dense granule release by blockade of P2Y12 signaling with MRS2395.
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p21 activated kinase signaling coordinates glycoprotein receptor VI-mediated platelet aggregation, lamellipodia formation, and aggregate stability under shear.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 02 May 2013
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
p21 activated kinase signaling ...... gregate stability under shear.
@en
p21 activated kinase signaling ...... gregate stability under shear.
@nl
type
label
p21 activated kinase signaling ...... gregate stability under shear.
@en
p21 activated kinase signaling ...... gregate stability under shear.
@nl
prefLabel
p21 activated kinase signaling ...... gregate stability under shear.
@en
p21 activated kinase signaling ...... gregate stability under shear.
@nl
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P2860
P1476
p21 activated kinase signaling ...... gregate stability under shear.
@en
P2093
Asako Itakura
Cassandra P Loren
Garth W Tormoen
Jiaqing Pang
Kristina M Haley
Owen J T McCarty
Sandra M Baker
P2860
P304
P356
10.1161/ATVBAHA.112.301165
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P577
2013-05-02T00:00:00Z