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Radiation-induced alterations in histone modification patterns and their potential impact on short-term radiation effectsDynamics of DNA damage response proteins at DNA breaks: a focus on protein modificationsMRE11 and RAD50, but not NBS1, are essential for gene targeting in the moss Physcomitrella patensCellular stress response and innate immune signaling: integrating pathways in host defense and inflammation.And-1 coordinates with CtIP for efficient homologous recombination and DNA damage checkpoint maintenanceKaposi Sarcoma Herpesvirus (KSHV) Latency-Associated Nuclear Antigen (LANA) recruits components of the MRN (Mre11-Rad50-NBS1) repair complex to modulate an innate immune signaling pathway and viral latencyRNF4-dependent hybrid SUMO-ubiquitin chains are signals for RAP80 and thereby mediate the recruitment of BRCA1 to sites of DNA damage.Saccharomyces cerevisiae as a model system to study the response to anticancer agents.Recruitment kinetics of DNA repair proteins Mdc1 and Rad52 but not 53BP1 depend on damage complexity.Mre11-Rad50-Nbs1 conformations and the control of sensing, signaling, and effector responses at DNA double-strand breaksDNA double-strand break repair in Caenorhabditis elegansRegulation of DNA damage responses and cell cycle progression by hMOB2.Evidence for distinct functions of MRE11 in Arabidopsis meiosis.The DNA damage response and checkpoint adaptation in Saccharomyces cerevisiae: distinct roles for the replication protein A2 (Rfa2) N-terminus.Interactions among Trypanosoma brucei RAD51 paralogues in DNA repair and antigenic variation.Identification of Mre11 as a target for heat radiosensitization.Identification of the interactors of human nibrin (NBN) and of its 26 kDa and 70 kDa fragments arising from the NBN 657del5 founder mutation.DNA-end capping by the budding yeast transcription factor and subtelomeric binding protein Tbf1The α2 helix in the DNA ligase IV BRCT-1 domain is required for targeted degradation of ligase IV during adenovirus infection.Cohesin codes - interpreting chromatin architecture and the many facets of cohesin function.Sharpening the ends for repair: mechanisms and regulation of DNA resection.NBN Gene Polymorphisms and Cancer Susceptibility: A Systemic Review.Eukaryotic DNA damage checkpoint activation in response to double-strand breaks.The accumulation of DNA repair defects is the molecular origin of carcinogenesis.DNA damage response in plants: conserved and variable response compared to animals.A computational platform for robotized fluorescence microscopy (II): DNA damage, replication, checkpoint activation, and cell cycle progression by high-content high-resolution multiparameter image-cytometry.Multiple functions of long non-coding RNAs in oxidative stress, DNA damage response and cancer progression.Zalypsis has in vitro activity in acute myeloid blasts and leukemic progenitor cells through the induction of a DNA damage response.Mre11 regulates CtIP-dependent double-strand break repair by interaction with CDK2.Impact of the MRN Complex on Adeno-Associated Virus Integration and Replication during Coinfection with Herpes Simplex Virus 1.Regulation of DNA-end resection by hnRNPU-like proteins promotes DNA double-strand break signaling and repairRadiation-induced telomere length variations in normal and in Nijmegen Breakage Syndrome cells.Post-translational methylations of the archaeal Mre11:Rad50 complex throughout the DNA damage response.DNA resection proteins Sgs1 and Exo1 are required for G1 checkpoint activation in budding yeast.4β-Hydroxywithanolide E selectively induces oxidative DNA damage for selective killing of oral cancer cells.A dynamic allosteric pathway underlies Rad50 ABC ATPase function in DNA repair.Arabidopsis thalianaMRE11 is essential for activation of cell cycle arrest, transcriptional regulation and DNA repair upon the induction of double-stranded DNA breaks.Targeting PFKFB3 radiosensitizes cancer cells and suppresses homologous recombination
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P2860
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 28 October 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
MRN and the race to the break.
@en
MRN and the race to the break.
@nl
type
label
MRN and the race to the break.
@en
MRN and the race to the break.
@nl
prefLabel
MRN and the race to the break.
@en
MRN and the race to the break.
@nl
P2860
P1433
P1476
MRN and the race to the break.
@en
P2093
Agnieszka Rupnik
P2860
P2888
P304
P356
10.1007/S00412-009-0242-4
P577
2009-10-28T00:00:00Z