Assembly of checkpoint and repair machineries at DNA damage sites.
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Structural basis of γH2AX recognition by human PTIP BRCT5-BRCT6 domains in the DNA damage response pathwayDifferential regulation of RNF8-mediated Lys48- and Lys63-based poly-ubiquitylationRing finger protein RNF169 antagonizes the ubiquitin-dependent signaling cascade at sites of DNA damageDynamics of DNA damage response proteins at DNA breaks: a focus on protein modificationsStructural basis for role of ring finger protein RNF168 RING domainStructural Insights into Recognition of MDC1 by TopBP1 in DNA Replication Checkpoint ControlAugmentation of response to chemotherapy by microRNA-506 through regulation of RAD51 in serous ovarian cancersA novel function of CRL4(Cdt2): regulation of the subunit structure of DNA polymerase δ in response to DNA damage and during the S phaseATM-dependent MiR-335 targets CtIP and modulates the DNA damage responseUSP51 deubiquitylates H2AK13,15ub and regulates DNA damage responseHistone demethylase KDM5B is a key regulator of genome stability.Histone H2A and H2B are monoubiquitinated at AID-targeted loci.Homeostatic control of polo-like kinase-1 engenders non-genetic heterogeneity in G2 checkpoint fidelity and timing.USP13 regulates the RAP80-BRCA1 complex dependent DNA damage response.Recruitment of DNA replication and damage response proteins to viral replication centers during infection with NS2 mutants of Minute Virus of Mice (MVM).Sensitivity to poly(ADP-ribose) polymerase (PARP) inhibition identifies ubiquitin-specific peptidase 11 (USP11) as a regulator of DNA double-strand break repair.NMR metabolomic profiling reveals new roles of SUMOylation in DNA damage responseA new non-catalytic role for ubiquitin ligase RNF8 in unfolding higher-order chromatin structure.DNA-PK, ATM and ATR collaboratively regulate p53-RPA interaction to facilitate homologous recombination DNA repairSpatiotemporal recruitment of human DNA polymerase delta to sites of UV damage.Chromatin remodeling, DNA damage repair and aging.The 53BP1-EXPAND1 connection in chromatin structure regulation.HERC2-USP20 axis regulates DNA damage checkpoint through Claspin.Critical roles of ring finger protein RNF8 in replication stress responses.Histone H4 lysine 16 hypoacetylation is associated with defective DNA repair and premature senescence in Zmpste24-deficient miceParaspeckle protein 1 (PSPC1) is involved in the cisplatin induced DNA damage response--role in G1/S checkpoint.DNA damage response is suppressed by the high cyclin-dependent kinase 1 activity in mitotic mammalian cellsInhibiting K63 polyubiquitination abolishes no-go type stalled translation surveillance in Saccharomyces cerevisiaeCDK-mediated RNF4 phosphorylation regulates homologous recombination in S-phase.Acetyltransferase p300 collaborates with chromodomain helicase DNA-binding protein 4 (CHD4) to facilitate DNA double-strand break repair.Tankyrases Promote Homologous Recombination and Check Point Activation in Response to DSBs.Deregulation of DNA damage response pathway by intercellular contactRequirement of ATM-dependent monoubiquitylation of histone H2B for timely repair of DNA double-strand breaks.Dissecting DNA damage response pathways by analysing protein localization and abundance changes during DNA replication stress.Direct quantification of gamma H2AX by cell-based high throughput screening for evaluation of genotoxicity of pesticides in a human thyroid cell lines.Focus on histone variant H2AX: to be or not to be.The ubiquitin specific protease USP34 promotes ubiquitin signaling at DNA double-strand breaksA phosphorylation-deubiquitination cascade regulates the BRCA2-RAD51 axis in homologous recombination.MicroRNAs: new players in the DNA damage response.The role of mitochondrial DNA damage in the citotoxicity of reactive oxygen species.
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Assembly of checkpoint and repair machineries at DNA damage sites.
description
article científic
@ca
article scientifique
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articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on 28 October 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Assembly of checkpoint and repair machineries at DNA damage sites.
@en
Assembly of checkpoint and repair machineries at DNA damage sites.
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type
label
Assembly of checkpoint and repair machineries at DNA damage sites.
@en
Assembly of checkpoint and repair machineries at DNA damage sites.
@nl
prefLabel
Assembly of checkpoint and repair machineries at DNA damage sites.
@en
Assembly of checkpoint and repair machineries at DNA damage sites.
@nl
P2860
P1476
Assembly of checkpoint and repair machineries at DNA damage sites.
@en
P2093
Junjie Chen
Michael S Y Huen
P2860
P304
P356
10.1016/J.TIBS.2009.09.001
P577
2009-10-28T00:00:00Z