Association with BiP and aggregation of class II MHC molecules synthesized in the absence of invariant chain.
about
Cloning and functional characterization of a subunit of the transporter associated with antigen processingInvariant chain made in Escherichia coli has an exposed N-terminal segment that blocks antigen binding to HLA-DR1 and a trimeric C-terminal segment that binds empty HLA-DR1Increased proteolysis of diphtheria toxin by human monocytes after heat shock: a subsidiary role for heat-shock protein 70 in antigen processing.A point mutation in the groove of HLA-DO allows egress from the endoplasmic reticulum independent of HLA-DM.Interaction of human immunodeficiency virus type 2 Vpx and invariant chain.Stoichiometry of HLA class II-invariant chain oligomersRole of heat shock proteins in protection from and pathogenesis of infectious diseases.Acute inducible ablation of GRP78 reveals its role in hematopoietic stem cell survival, lymphogenesis and regulation of stress signaling.Role of heat shock proteins in diseases and their therapeutic potential.Invariant chain protects class II histocompatibility antigens from binding intact polypeptides in the endoplasmic reticulum.Misfolded major histocompatibility complex class I molecules accumulate in an expanded ER-Golgi intermediate compartmentAggregation as a determinant of protein fate in post-Golgi compartments: role of the luminal domain of furin in lysosomal targetingThe CLIP region of invariant chain plays a critical role in regulating major histocompatibility complex class II folding, transport, and peptide occupancyBinding of major histocompatibility complex class II to the invariant chain-derived peptide, CLIP, is regulated by allelic polymorphism in class II.Invariant chain cleavage and peptide loading in major histocompatibility complex class II vesicles.Inhibition of invariant chain (Ii)-calnexin interaction results in enhanced degradation of Ii but does not prevent the assembly of alpha beta Ii complexesRelated leucine-based cytoplasmic targeting signals in invariant chain and major histocompatibility complex class II molecules control endocytic presentation of distinct determinants in a single protein.A lysosomal targeting signal in the cytoplasmic tail of the beta chain directs HLA-DM to MHC class II compartments.Increased immunogenicity is an integral part of the heat shock response following renal ischemia.Assembly of HLA DR1 molecules translated in vitro: binding of peptide in the endoplasmic reticulum precludes association with invariant chain.Evidence for a conformational change in a class II major histocompatibility complex molecule occurring in the same pH range where antigen binding is enhanced.
P2860
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P2860
Association with BiP and aggregation of class II MHC molecules synthesized in the absence of invariant chain.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on February 1994
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Association with BiP and aggre ...... he absence of invariant chain.
@en
Association with BiP and aggre ...... he absence of invariant chain.
@nl
type
label
Association with BiP and aggre ...... he absence of invariant chain.
@en
Association with BiP and aggre ...... he absence of invariant chain.
@nl
prefLabel
Association with BiP and aggre ...... he absence of invariant chain.
@en
Association with BiP and aggre ...... he absence of invariant chain.
@nl
P2093
P2860
P1433
P1476
Association with BiP and aggre ...... the absence of invariant chain
@en
P2093
Bonifacino JS
Bonnerot C
Germain RN
Robertson EJ
P2860
P304
P356
10.1002/J.1460-2075.1994.TB06338.X
P407
P577
1994-02-01T00:00:00Z