Phenotypes in mTERT⁺/⁻ and mTERT⁻/⁻ mice are due to short telomeres, not telomere-independent functions of telomerase reverse transcriptase - Wikidata - awgldk - TriplyDB

Phenotypes in mTERT⁺/⁻ and mTERT⁻/⁻ mice are due to short telomeres, not telomere-independent functions of telomerase reverse transcriptase

Phenotypes in mTERT⁺/⁻ and mTERT⁻/⁻ mice are due to short telomeres, not telomere-independent functions of telomerase reverse transcriptase

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The telomere syndromes Telomerase: The Devil Inside Candidate genes of idiopathic pulmonary fibrosis: current evidence and research Telomerase and idiopathic pulmonary fibrosis Implications of telomere-independent activities of telomerase reverse transcriptase in human cancer Do telomeres adapt to physiological stress? Exploring the effect of exercise on telomere length and telomere-related proteins Axis of ageing: telomeres, p53 and mitochondria Loss-of-function mutations in the RNA biogenesis factor NAF1 predispose to pulmonary fibrosis-emphysema Many disease-associated variants of hTERT retain high telomerase enzymatic activity HPV16 E7 protein and hTERT proteins defective for telomere maintenance cooperate to immortalize human keratinocytes Telomeres shorten in response to oxidative stress in mouse skeletal muscle fibers Telomerase reverse transcriptase in the regulation of gene expression.Cytoplasmic TERT Associates to RNA Granules in Fully Mature Neurons: Role in the Translational Control of the Cell Cycle Inhibitor p15INK4B Reversibility of Defective Hematopoiesis Caused by Telomere Shortening in Telomerase Knockout Mice.Native gel electrophoresis of human telomerase distinguishes active complexes with or without dyskerin.Cancer-associated TERT promoter mutations abrogate telomerase silencing Wnt signaling regulates homeostasis of the periodontal ligament.Telomere-independent functions of telomerase in nuclei, cytoplasm, and mitochondria Telomeres and Telomerase in the Radiation Response: Implications for Instability, Reprograming, and Carcinogenesis.Telomerase Deficiency Causes Alveolar Stem Cell Senescence-associated Low-grade Inflammation in Lungs.Genetic studies provide clues on the pathogenesis of idiopathic pulmonary fibrosis.Assessing cell and organ senescence biomarkers Telomeres and age-related disease: how telomere biology informs clinical paradigms Telomeres, a busy platform for cell signaling.Telomere dynamics in mice and humans The role of telomeres and telomerase reverse transcriptase isoforms in pluripotency induction and maintenance Telomerase and estrogen-sensing activities are essential for continued mammary growth in vivo but dispensable for "reprogramming" neural stem cells.Essential role for mammalian apurinic/apyrimidinic (AP) endonuclease Ape1/Ref-1 in telomere maintenance.Telomerase reverse transcriptase promotes cancer cell proliferation by augmenting tRNA expression Telomerase at the intersection of cancer and aging.An investigation of the effects of the core protein telomerase reverse transcriptase on Wnt signaling in breast cancer cells.Potential of telomerase activation in extending health span and longevity.The role of telomere shortening in somatic stem cells and tissue aging: lessons from telomerase model systems.Telomeres and tissue engineering: the potential roles of TERT in VEGF-mediated angiogenesis.Transcriptional outcome of telomere signalling.Cardiac telomere length in heart development, function, and disease.Association between telomere length and survival in patients with idiopathic pulmonary fibrosis.Excitotoxic and Radiation Stress Increase TERT Levels in the Mitochondria and Cytosol of Cerebellar Purkinje Neurons.Telomerase reverse transcriptase promotes epithelial-mesenchymal transition and stem cell-like traits in cancer cells.Long telomeres bypass the requirement for telomere maintenance in human tumorigenesis.

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Phenotypes in mTERT⁺/⁻ and mTERT⁻/⁻ mice are due to short telomeres, not telomere-independent functions of telomerase reverse transcriptase

http://www.wikidata.org/entity/Q35096706

description

2011 nî lūn-bûn

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2011 թուականի Ապրիլին հրատարակուած գիտական յօդուած

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2011 թվականի ապրիլին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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Phenotypes in mTERT⁺/⁻ and mTE ...... lomerase reverse transcriptase

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Phenotypes in mTERT⁺/⁻ and mTE ...... lomerase reverse transcriptase

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Phenotypes in mTERT⁺/⁻ and mTE ...... lomerase reverse transcriptase

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Phenotypes in mTERT⁺/⁻ and mTE ...... lomerase reverse transcriptase

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Phenotypes in mTERT⁺/⁻ and mTE ...... lomerase reverse transcriptase

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Phenotypes in mTERT⁺/⁻ and mTE ...... lomerase reverse transcriptase

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Phenotypes in mTERT⁺/⁻ and mTE ...... lomerase reverse transcriptase

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Baktiar Karim

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Huimin Yu

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Nini Guo

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Sofia L Vidal-Cardenas

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P2860

A telomerase component is defective in the human disease dyskeratosis congenita

Telomerase modulates Wnt signalling by association with target gene chromatin

An RNA-dependent RNA polymerase formed by TERT and the RMRP RNA

Wild-derived inbred mouse strains have short telomeres.

Haploinsufficiency of telomerase reverse transcriptase leads to anticipation in autosomal dominant dyskeratosis congenita

The Wnt signaling pathway in development and disease

MEC3, MEC1, and DDC2 are essential components of a telomere checkpoint pathway required for cell cycle arrest during senescence in Saccharomyces cerevisiae.

Requirement for Wnt3 in vertebrate axis formation

For better or worse? Telomerase inhibition and cancer

Telomere dysfunction impairs DNA repair and enhances sensitivity to ionizing radiation

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2369-2379

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10.1128/MCB.05312-11

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12

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31

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Margaret A Strong

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2011-04-04T00:00:00Z

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21464209

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3133422

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