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Mechanisms underlying the cardiac pacemaker: the role of SK4 calcium-activated potassium channelsPacemaker Created in Human Ventricle by Depressing Inward-Rectifier K⁺ Current: A Simulation StudyIdentification and functional characterization of cardiac pacemaker cells in zebrafishPitx2c is reactivated in the failing myocardium and stimulates myf5 expression in cultured cardiomyocytesErbb2 is required for cardiac atrial electrical activity during developmentThe cardiac conduction systemLethal arrhythmias in Tbx3-deficient mice reveal extreme dosage sensitivity of cardiac conduction system function and homeostasisNotch signaling regulates murine atrioventricular conduction and the formation of accessory pathways.Defective Tbx2-dependent patterning of the atrioventricular canal myocardium causes accessory pathway formation in miceThe Popeye domain containing 2 (popdc2) gene in zebrafish is required for heart and skeletal muscle development.Direct conversion of quiescent cardiomyocytes to pacemaker cells by expression of Tbx18.Expression and distribution of voltage-gated ion channels in ferret sinoatrial nodeTbx2 and Tbx3 induce atrioventricular myocardial development and endocardial cushion formationTranscriptional suppression of connexin43 by TBX18 undermines cell-cell electrical coupling in postnatal cardiomyocytesFunctional redundancy between human SHOX and mouse Shox2 genes in the regulation of sinoatrial node formation and pacemaking function.Structure and function of the hearts of lizards and snakes.SHOX2 overexpression favors differentiation of embryonic stem cells into cardiac pacemaker cells, improving biological pacing ability.The short stature homeobox 2 (Shox2)-bone morphogenetic protein (BMP) pathway regulates dorsal mesenchymal protrusion development and its temporary function as a pacemaker during cardiogenesis.Phosphorylation of Shox2 is required for its function to control sinoatrial node formation.Long-range regulatory interactions at the 4q25 atrial fibrillation risk locus involve PITX2c and ENPEP.Tbx20 regulation of cardiac cell proliferation and lineage specialization during embryonic and fetal development in vivo.A common Shox2-Nkx2-5 antagonistic mechanism primes the pacemaker cell fate in the pulmonary vein myocardium and sinoatrial node.Transcription factor ISL1 is essential for pacemaker development and function.Identifying the evolutionary building blocks of the cardiac conduction system.Cardiomyogenesis of embryonic stem cells upon purinergic receptor activation by ADP and ATP.Cell-cell junction remodeling in the heart: possible role in cardiac conduction system function and arrhythmias?Genetic Regulation of Sinoatrial Node Development and Pacemaker Program in the Venous PoleIdentification of a Tbx1/Tbx2/Tbx3 genetic pathway governing pharyngeal and arterial pole morphogenesisBiology of the Sinus Node and its Disease.SK4 Ca2+ activated K+ channel is a critical player in cardiac pacemaker derived from human embryonic stem cells.The role of Wnt regulation in heart development, cardiac repair and disease: A tissue engineering perspective.The G-protein-gated K+ channel, IKACh, is required for regulation of pacemaker activity and recovery of resting heart rate after sympathetic stimulationMyocardial lineage development.Electrophysiological patterning of the heart.The anatomy of the conduction system: implications for the clinical cardiologist.A molecular and genetic outline of cardiac morphogenesis.Comparative cardiovascular physiology: future trends, opportunities and challenges.Urinary tract pacemaker cells: current knowledge and insights from nonrenal pacemaker cells provide a basis for future discovery.Molecular regulation of cardiomyocyte differentiation.Genetic variation in T-box binding element functionally affects SCN5A/SCN10A enhancer.
P2860
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P2860
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on February 2010
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Development of the pacemaker tissues of the heart.
@en
Development of the pacemaker tissues of the heart.
@nl
type
label
Development of the pacemaker tissues of the heart.
@en
Development of the pacemaker tissues of the heart.
@nl
prefLabel
Development of the pacemaker tissues of the heart.
@en
Development of the pacemaker tissues of the heart.
@nl
P1433
P1476
Development of the pacemaker tissues of the heart
@en
P2093
Andreas Kispert
Antoon F M Moorman
P304
P356
10.1161/CIRCRESAHA.109.205419
P577
2010-02-01T00:00:00Z