RAR-specific agonist/antagonists which dissociate transactivation and AP1 transrepression inhibit anchorage-independent cell proliferation.
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Retinoic acid receptors inhibit AP1 activation by regulating extracellular signal-regulated kinase and CBP recruitment to an AP1-responsive promoter.TIF2, a 160 kDa transcriptional mediator for the ligand-dependent activation function AF-2 of nuclear receptorsDifferential ligand-dependent interactions between the AF-2 activating domain of nuclear receptors and the putative transcriptional intermediary factors mSUG1 and TIF1Oral administration of a retinoic Acid receptor antagonist reversibly inhibits spermatogenesis in miceModulators of the structural dynamics of the retinoid X receptor to reveal receptor functionGene regulation of CYP4F11 in human keratinocyte HaCaT cells.Dual RXR Agonists and RAR Antagonists Based on the Stilbene Retinoid Scaffold.A mutation mimicking ligand-induced conformational change yields a constitutive RXR that senses allosteric effects in heterodimers.ATM-NF-kappaB connection as a target for tumor radiosensitizationKrüppel-like factor 5 mediates the transforming activity of oncogenic H-RasRetinoid pathway and cancer therapeuticsRetinoic acid enhances Foxp3 induction indirectly by relieving inhibition from CD4+CD44hi Cells.An Unexpected Mode Of Binding Defines BMS948 as A Full Retinoic Acid Receptor β (RARβ, NR1B2) Selective Agonist.Specific and redundant functions of retinoid X Receptor/Retinoic acid receptor heterodimers in differentiation, proliferation, and apoptosis of F9 embryonal carcinoma cells.Retinoids regulate survival and antigen presentation by immature dendritic cells.A regulatory cascade involving retinoic acid, Cbfa1, and matrix metalloproteinases is coupled to the development of a process of perichondrial invasion and osteogenic differentiation during bone formationNF-kappa B-mediated adaptive resistance to ionizing radiation.Synergistic activation of retinoic acid (RA)-responsive genes and induction of embryonal carcinoma cell differentiation by an RA receptor alpha (RAR alpha)-, RAR beta-, or RAR gamma-selective ligand in combination with a retinoid X receptor-specificDistinct retinoid X receptor-retinoic acid receptor heterodimers are differentially involved in the control of expression of retinoid target genes in F9 embryonal carcinoma cells.Loss of growth inhibitory effects of retinoic acid in human breast cancer cells following long-term exposure to retinoic acidHER-2 and NF-kappaB as the targets for therapy-resistant breast cancer.Retinoid signaling during spermatogenesis as revealed by genetic and metabolic manipulations of retinoic acid receptor alpha.Pharmacological activity of retinoic acid receptor alpha-selective antagonists in vitro and in vivo.Dynamic and combinatorial control of gene expression by nuclear retinoic acid receptors (RARs).Cell-type and promoter-context dependent retinoic acid receptor (RAR) redundancies for RAR beta 2 and Hoxa-1 activation in F9 and P19 cells can be artefactually generated by gene knockouts.A nuclear hormone receptor corepressor mediates transcriptional silencing by receptors with distinct repression domains.A novel role for helix 12 of retinoid X receptor in regulating repression.The N-CoR/histone deacetylase 3 complex is required for repression by thyroid hormone receptor.Retinoic acid inhibits induction of c-Jun protein by ultraviolet radiation that occurs subsequent to activation of mitogen-activated protein kinase pathways in human skin in vivo.Rational design of RAR-selective ligands revealed by RARbeta crystal stucture.CSK controls retinoic acid receptor (RAR) signaling: a RAR-c-SRC signaling axis is required for neuritogenic differentiation.Nuclear hormone receptor antagonism with AP-1 by inhibition of the JNK pathway.Treatment of melanoma cells with the synthetic retinoid CD437 induces apoptosis via activation of AP-1 in vitro, and causes growth inhibition in xenografts in vivo.Synergistic inhibition of prostate cancer cell lines by a 19-nor hexafluoride vitamin D3 analogue and anti-activator protein 1 retinoid.Serum microRNAs as predictors of risk for non-muscle invasive bladder cancer.
P2860
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P2860
RAR-specific agonist/antagonists which dissociate transactivation and AP1 transrepression inhibit anchorage-independent cell proliferation.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on March 1995
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
RAR-specific agonist/antagonis ...... ndependent cell proliferation.
@en
RAR-specific agonist/antagonis ...... ndependent cell proliferation.
@nl
type
label
RAR-specific agonist/antagonis ...... ndependent cell proliferation.
@en
RAR-specific agonist/antagonis ...... ndependent cell proliferation.
@nl
prefLabel
RAR-specific agonist/antagonis ...... ndependent cell proliferation.
@en
RAR-specific agonist/antagonis ...... ndependent cell proliferation.
@nl
P2093
P2860
P1433
P1476
RAR-specific agonist/antagonis ...... independent cell proliferation
@en
P2093
Balaguer P
Gronemeyer H
Ostrowski J
Starrett JE
P2860
P304
P356
10.1002/J.1460-2075.1995.TB07102.X
P407
P577
1995-03-01T00:00:00Z