The MHC class I-like Fc receptor promotes humorally mediated autoimmune disease.
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Immune complexes as therapy for autoimmunityThe antiinflammatory activity of IgG: the intravenous IgG paradoxThe role of the complement and the Fc gamma R system in the pathogenesis of arthritisTargeting the Fc receptor in autoimmune diseaseIgG placental transfer in healthy and pathological pregnanciesThe neonatal Fc receptor, FcRn, as a target for drug delivery and therapyReduction of IgG in nonhuman primates by a peptide antagonist of the neonatal Fc receptor FcRn.Gene expression analysis of interferon kappa in laser capture microdissected cervical epitheliumCan antibodies with specificity for soluble antigens mimic the therapeutic effects of intravenous IgG in the treatment of autoimmune disease?A novel murine model of fetal and neonatal alloimmune thrombocytopenia: response to intravenous IgG therapy.Targeting FcRn for therapy: from live cell imaging to in vivo studies in mice.Neonatal Fc receptor for IgG regulates mucosal immune responses to luminal bacteriaRegulation of immune responses by the neonatal fc receptor and its therapeutic implicationsNeonatal Fc receptor for IgG (FcRn) regulates cross-presentation of IgG immune complexes by CD8-CD11b+ dendritic cells.p21Cip1 is required for the development of monocytes and their response to serum transfer-induced arthritis.Neonatal Fc receptor blockade by Fc engineering ameliorates arthritis in a murine model.Absence of β2 integrins impairs regulatory T cells and exacerbates CD4+ T cell-dependent autoimmune carditisThe Paf oncogene is essential for hematopoietic stem cell function and development.Fully human monoclonal antibody inhibitors of the neonatal fc receptor reduce circulating IgG in non-human primates.Genetically engineered humanized mouse models for preclinical antibody studies.Analysis of Response Elements Involved in the Regulation of the Human Neonatal Fc Receptor Gene (FCGRT).Activation of peroxisome proliferator-activated receptor gamma (PPARgamma) by rosiglitazone suppresses components of the insulin-like growth factor regulatory system in vitro and in vivoAn essential role for IL-17 in preventing pathogen-initiated bone destruction: recruitment of neutrophils to inflamed bone requires IL-17 receptor-dependent signals.Improved tumor imaging and therapy via i.v. IgG-mediated time-sequential modulation of neonatal Fc receptor.Monoclonal antibodies directed against human FcRn and their applications.MHC class I family proteins retard systemic lupus erythematosus autoimmunity and B cell lymphomagenesis.Human antibodies induce arthritis in mice deficient in the low-affinity inhibitory IgG receptor Fc gamma RIIB.The immunologic functions of the neonatal Fc receptor for IgGAntibody-induced arthritis: disease mechanisms and genes involved at the effector phase of arthritis.Quantitative dynamic models of arthritis progression in the ratThe MHC class II-associated invariant chain interacts with the neonatal Fc gamma receptor and modulates its trafficking to endosomal/lysosomal compartments.NF-kappaB signaling regulates functional expression of the MHC class I-related neonatal Fc receptor for IgG via intronic binding sequences.Activation of the JAK/STAT-1 signaling pathway by IFN-gamma can down-regulate functional expression of the MHC class I-related neonatal Fc receptor for IgG.Loss of parasympathetic innervation leads to sustained expression of pro-inflammatory genes in the rat lacrimal gland.Role of Fc Receptors as a therapeutic target.An FcRn-dependent role for anti-flagellin immunoglobulin G in pathogenesis of colitis in mice.Immune and non-immune functions of the (not so) neonatal Fc receptor, FcRn.Inhibitors of the FcRn:IgG protein-protein interaction.Chapter 4: Multitasking by exploitation of intracellular transport functions the many faces of FcRn.The other side of immunoglobulin G: suppressor of inflammation.
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The MHC class I-like Fc receptor promotes humorally mediated autoimmune disease.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on May 2004
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
The MHC class I-like Fc receptor promotes humorally mediated autoimmune disease.
@en
The MHC class I-like Fc receptor promotes humorally mediated autoimmune disease.
@nl
type
label
The MHC class I-like Fc receptor promotes humorally mediated autoimmune disease.
@en
The MHC class I-like Fc receptor promotes humorally mediated autoimmune disease.
@nl
prefLabel
The MHC class I-like Fc receptor promotes humorally mediated autoimmune disease.
@en
The MHC class I-like Fc receptor promotes humorally mediated autoimmune disease.
@nl
P2093
P2860
P356
P1476
The MHC class I-like Fc receptor promotes humorally mediated autoimmune disease.
@en
P2093
Daniel J Shaffer
Derry Roopenian
Gregory J Christianson
Shreeram Akilesh
Stefka Petkova
Thomas J Sproule
P2860
P304
P356
10.1172/JCI18838
P407
P577
2004-05-01T00:00:00Z