Biology of Aurora A kinase: implications in cancer manifestation and therapy.
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Protein phosphatase 6 regulates mitotic spindle formation by controlling the T-loop phosphorylation state of Aurora A bound to its activator TPX2Recent advances in the development of Aurora kinases inhibitors in hematological malignanciesAurora Kinase A expression predicts platinum-resistance and adverse outcome in high-grade serous ovarian carcinoma patients.Aurora kinase-A deficiency during skin development impairs cell division and stratificationTargeting high Aurora kinases expression as an innovative therapy for hepatocellular carcinoma.A new aurora in anaplastic thyroid cancer therapy.The WW-HECT protein Smurf2 interacts with the Docking Protein NEDD9/HEF1 for Aurora A activation.Targeting Aurora kinase-A downregulates cell proliferation and angiogenesis in neuroblastoma.Weighted frequent gene co-expression network mining to identify genes involved in genome stability.Update on aurora kinase inhibitors in gynecologic malignancies.Update on Aurora Kinase Targeted Therapeutics in Oncology.Inhibition of Aurora-A kinase induces cell cycle arrest in epithelial ovarian cancer stem cells by affecting NFĸB pathway.Inhibition of Aurora A promotes chemosensitivity via inducing cell cycle arrest and apoptosis in cervical cancer cells.A functional cooperativity between Aurora A kinase and LIM kinase1: implication in the mitotic processCo-inhibition of polo-like kinase 1 and Aurora kinases promotes mitotic catastrophe.Myc, Aurora Kinase A, and mutant p53(R172H) co-operate in a mouse model of metastatic skin carcinoma.Dual targeting of mTOR and aurora-A kinase for the treatment of uterine Leiomyosarcoma.Aurora A kinase (AURKA) in normal and pathological cell division.The investigational Aurora kinase A inhibitor MLN8237 induces defects in cell viability and cell-cycle progression in malignant bladder cancer cells in vitro and in vivo.A novel aurora-A inhibitor, BPR1K0609S1, sensitizes colorectal tumor cells to 5-fluorofracil (5-FU) treatmentAurora kinase A activates the vacuolar H+-ATPase (V-ATPase) in kidney carcinoma cellsAurora Kinase A is a Biomarker for Bladder Cancer Detection and Contributes to its Aggressive Behavior.Immunohistochemical/histochemical double staining method in the study of the columnar metaplasia of the oesophagus.The Aurora kinase A inhibitor TC-A2317 disrupts mitotic progression and inhibits cancer cell proliferation.Aurora A mediates cross-talk between N- and C-terminal post-translational modifications of p53Control of Aurora-A stability through interaction with TPX2.Elevated aurora kinase a protein expression in diabetic skin tissue.Therapeutic potential of mitotic interaction between the nucleoporin Tpr and aurora kinase A.The Effect of Aurora Kinase Inhibitor on Adhesion and Migration in Human Breast Cancer Cells and Clinical Implications.Analysis of potential genes associated with primary cilia in bladder cancer
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Biology of Aurora A kinase: implications in cancer manifestation and therapy.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on March 2010
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Biology of Aurora A kinase: implications in cancer manifestation and therapy.
@en
Biology of Aurora A kinase: implications in cancer manifestation and therapy.
@nl
type
label
Biology of Aurora A kinase: implications in cancer manifestation and therapy.
@en
Biology of Aurora A kinase: implications in cancer manifestation and therapy.
@nl
prefLabel
Biology of Aurora A kinase: implications in cancer manifestation and therapy.
@en
Biology of Aurora A kinase: implications in cancer manifestation and therapy.
@nl
P2093
P2860
P356
P1476
Biology of Aurora A kinase: implications in cancer manifestation and therapy.
@en
P2093
Dhanasekaran Karthigeyan
Jayasha Shandilya
Sallekoppal B Benaka Prasad
Shipra Agrawal
Tapas K Kundu
P2860
P304
P356
10.1002/MED.20203
P577
2010-03-01T00:00:00Z