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HDAC6 as a target for neurodegenerative diseases: what makes it different from the other HDACs?Mechanisms of Histone Deacetylase Inhibitor-Regulated Gene Expression in Cancer CellsLysine deacetylase (KDAC) regulatory pathways: an alternative approach to selective modulationBioactive heterocycles containing endocyclic N-hydroxy groupsHistone Deacetylase (HDAC) Inhibitor Kinetic Rate Constants Correlate with Cellular Histone Acetylation but Not Transcription and Cell ViabilityA Rational Approach for the Identification of Non-Hydroxamate HDAC6-Selective InhibitorsScreening of selective histone deacetylase inhibitors by proteochemometric modeling.Inhibition and mechanism of HDAC8 revisited.Utilization of Boron Compounds for the Modification of Suberoyl Anilide Hydroxamic Acid as Inhibitor of Histone Deacetylase Class II Homo sapiens.Synthesis and biological evaluation of largazole analogues with modified surface recognition cap groupsComputational exploration of zinc binding groups for HDAC inhibitionHistone deacetylase inhibitor activity in royal jelly might facilitate caste switching in bees.Interpreting clinical assays for histone deacetylase inhibitors.Phase II study of belinostat in patients with recurrent or refractory advanced thymic epithelial tumors.Antitumor mechanisms of amino Acid hydroxyurea derivatives in the metastatic colon cancer model.Discovery of HDAC inhibitors with potent activity against multiple malaria parasite life cycle stagesComputational design of a time-dependent histone deacetylase 2 selective inhibitor.Roles and post-translational regulation of cardiac class IIa histone deacetylase isoforms.HDACiDB: a database for histone deacetylase inhibitors.Search for the pharmacophore of histone deacetylase inhibitors using pharmacophore query and docking studyHistone Deacetylase 3 and 4 Complex Stimulates the Transcriptional Activity of the Mineralocorticoid Receptor.Fragment based G-QSAR and molecular dynamics based mechanistic simulations into hydroxamic-based HDAC inhibitors against spinocerebellar ataxia.Rational design and diversity-oriented synthesis of peptoid-based selective HDAC6 inhibitors.HDAC1 and HDAC2 are differentially expressed in endometriosis.Design, synthesis, and antitumor evaluation of novel histone deacetylase inhibitors equipped with a phenylsulfonylfuroxan module as a nitric oxide donorHistone deacetylase inhibitors suppress mutant p53 transcription via histone deacetylase 8.HDAC5 is required for maintenance of pericentric heterochromatin, and controls cell-cycle progression and survival of human cancer cells.Discovery of a Novel HDAC2 Inhibitor by a Scaffold-Merging Hybrid QueryHDAC9 is implicated in schizophrenia and expressed specifically in post-mitotic neurons but not in adult neural stem cells.Role of Hydroxamate-Based Histone Deacetylase Inhibitors (Hb-HDACIs) in the Treatment of Solid MalignanciesDevelopment of high-content assays for kidney progenitor cell expansion in transgenic zebrafish.Antidepressant-like properties of novel HDAC6-selective inhibitors with improved brain bioavailability.Targeting binding partners of the CBFβ-SMMHC fusion protein for the treatment of inversion 16 acute myeloid leukemia.Histone deacetylase inhibitors: potential targets responsible for their anti-cancer effect.Histone deacetylase inhibitors as therapeutic agents for acute central nervous system injuries.Inhibition of histone deacetylases in inflammatory bowel diseases.Bromodomains as therapeutic targets.Lysine acetylation in obesity, diabetes and metabolic disease.Epigenetics of autoimmune diabetes.Valproic acid for the treatment of malignant gliomas: review of the preclinical rationale and published clinical results.
P2860
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P2860
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 14 February 2010
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Inside HDAC with HDAC inhibitors.
@en
Inside HDAC with HDAC inhibitors.
@nl
type
label
Inside HDAC with HDAC inhibitors.
@en
Inside HDAC with HDAC inhibitors.
@nl
prefLabel
Inside HDAC with HDAC inhibitors.
@en
Inside HDAC with HDAC inhibitors.
@nl
P1476
Inside HDAC with HDAC inhibitors.
@en
P2093
Philippe Bertrand
P304
P356
10.1016/J.EJMECH.2010.02.030
P577
2010-02-14T00:00:00Z