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Maternal undernutrition and cardiometabolic disease: a Latin American perspectiveThe metabolic advantage of tumor cellsPhosphofructokinase 1 glycosylation regulates cell growth and metabolismDeath-associated protein kinase increases glycolytic rate through binding and activation of pyruvate kinaseTargeting cellular metabolism to improve cancer therapeuticsStable isotope-resolved metabolomics and applications for drug developmentArginine Metabolism in Bacterial Pathogenesis and Cancer TherapyTargeting metabolism in breast cancer: How far we can go?Hypoxia and metabolic adaptation of cancer cellsDevelopment, Maintenance, and Reversal of Multiple Drug Resistance: At the Crossroads of TFPI1, ABC Transporters, and HIF1Mitochondrial Dysfunction and Disturbed Coherence: Gate to Cancer.Dysregulated metabolism contributes to oncogenesisSirtuins in Cancer: a Balancing Act between Genome Stability and MetabolismTunneling nanotubes provide a unique conduit for intercellular transfer of cellular contents in human malignant pleural mesotheliomaPyruvate kinase M2 activators promote tetramer formation and suppress tumorigenesisSerine is a natural ligand and allosteric activator of pyruvate kinase M2Phosphoglycerate Mutase 1 Coordinates Glycolysis and Biosynthesis to Promote Tumor GrowthTyr26 phosphorylation of PGAM1 provides a metabolic advantage to tumours by stabilizing the active conformationStructural basis for the allosteric inhibitory mechanism of human kidney-type glutaminase (KGA) and its regulation by Raf-Mek-Erk signaling in cancer cell metabolismKRAS Genotype Correlates with Proteasome Inhibitor Ixazomib Activity in Preclinical In Vivo Models of Colon and Non-Small Cell Lung Cancer: Potential Role of Tumor Metabolism.Sirtuins in metabolism, DNA repair and cancerThe altered glucose metabolism in tumor and a tumor acidic microenvironment associated with extracellular matrix metalloproteinase inducer and monocarboxylate transportersROS homeostasis and metabolism: a critical liaison for cancer therapyMetabolic consequences of oncogenic IDH mutationsEmerging concepts in the molecular basis of pulmonary arterial hypertension: part I: metabolic plasticity and mitochondrial dynamics in the pulmonary circulation and right ventricle in pulmonary arterial hypertensionMitochondrial phosphoenolpyruvate carboxykinase (PEPCK-M) is a pro-survival, endoplasmic reticulum (ER) stress response gene involved in tumor cell adaptation to nutrient availabilityA robust tool for discriminative analysis and feature selection in paired samples impacts the identification of the genes essential for reprogramming lung tissue to adenocarcinomaReconstruction of Tissue-Specific Metabolic Networks Using CORDAStructure-based development of small molecule PFKFB3 inhibitors: a framework for potential cancer therapeutic agents targeting the Warburg effectNon-equilibrium hyperbolic transport in transcriptional regulationIdentification of 5-Iodotubercidin as a genotoxic drug with anti-cancer potentialAscorbic acid and a cytostatic inhibitor of glycolysis synergistically induce apoptosis in non-small cell lung cancer cellsProteomic analysis of signaling network regulation in renal cell carcinomas with differential hypoxia-inducible factor-2α expressionDichloroacetate enhances adriamycin-induced hepatoma cell toxicity in vitro and in vivo by increasing reactive oxygen species levelsDeregulation of mitochondrial ATPsyn-β in acute myeloid leukemia cells and with increased drug resistanceApoptotic efficacy of etomoxir in human acute myeloid leukemia cells. Cooperation with arsenic trioxide and glycolytic inhibitors, and regulation by oxidative stress and protein kinase activitiesBEMER Electromagnetic Field Therapy Reduces Cancer Cell Radioresistance by Enhanced ROS Formation and Induced DNA DamageExpression, regulation and function of phosphofructo-kinase/fructose-biphosphatases (PFKFBs) in glucocorticoid-induced apoptosis of acute lymphoblastic leukemia cells.Cancer stem cell theory and the warburg effect, two sides of the same coin?Metabolic targeting of malignant tumors: small-molecule inhibitors of bioenergetic flux.
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P2860
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 19 March 2010
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Targeting metabolic transformation for cancer therapy.
@en
Targeting metabolic transformation for cancer therapy.
@nl
type
label
Targeting metabolic transformation for cancer therapy.
@en
Targeting metabolic transformation for cancer therapy.
@nl
prefLabel
Targeting metabolic transformation for cancer therapy.
@en
Targeting metabolic transformation for cancer therapy.
@nl
P50
P356
P1476
Targeting metabolic transformation for cancer therapy
@en
P2093
Raúl V Durán
P2888
P304
P356
10.1038/NRC2817
P407
P577
2010-03-19T00:00:00Z