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Keeping mtDNA in shape between generationsAntimutator alleles of yeast DNA polymerase gamma modulate the balance between DNA synthesis and excisionLRPPRC is necessary for polyadenylation and coordination of translation of mitochondrial mRNAsDNA Damage and Repair in Schizophrenia and Autism: Implications for Cancer Comorbidity and BeyondMitochondrial Oxidative Stress, Mitochondrial DNA Damage and Their Role in Age-Related Vascular DysfunctionMitochondrial biology and Parkinson's diseaseSOD2 deficiency promotes aging phenotypes in mouse skinCytoplasmic hybrid (cybrid) cell lines as a practical model for mitochondriopathiesMechanism of homologous recombination and implications for aging-related deletions in mitochondrial DNAModelling age-related metabolic disorders in the mouseMitochondrial inverted repeats strongly correlate with lifespan: mtDNA inversions and agingOxidative stress is not a major contributor to somatic mitochondrial DNA mutationsMgm101 is a Rad52-related protein required for mitochondrial DNA recombination.The mitochondrial contact site complex, a determinant of mitochondrial architecture.Inflammation, Iron, Energy Failure, and Oxidative Stress in the Pathogenesis of Multiple SclerosisDeclining NAD(+) induces a pseudohypoxic state disrupting nuclear-mitochondrial communication during agingMitochondrial genomic variation associated with higher mitochondrial copy number: the Cache County Study on Memory Health and AgingDetectable clonal mosaicism in the human genomeCurrent versus future reproduction and longevity: a re-evaluation of predictions and mechanismsAccumulation of DNA damage in the aged hematopoietic stem cell compartmentThe ageing genome, clonal mosaicism and chronic disease.Dissecting the mechanisms underlying the accumulation of mitochondrial DNA deletions in human skeletal muscle.Overexpression of the mitochondrial methyltransferase TFB1M in the mouse does not impact mitoribosomal methylation status or hearing.Endurance exercise rescues progeroid aging and induces systemic mitochondrial rejuvenation in mtDNA mutator miceImpaired mitochondrial transport and Parkin-independent degeneration of respiratory chain-deficient dopamine neurons in vivoBiology and genetics of prions causing neurodegenerationMitochondrial DNA deletions and depletion within paraspinal musclesUltra-deep sequencing of mouse mitochondrial DNA: mutational patterns and their origins.Long-term health of dopaminergic neuron transplants in Parkinson's disease patients.Mitochondrial DNA association study of type 2 diabetes with or without ischemic stroke in Taiwan.Amelioration of oral mucositis pain by NASA near-infrared light-emitting diodes in bone marrow transplant patients.Nothobranchius as a model for aging studies. A review.Taking a "good" look at free radicals in the aging process.Animal Mitochondrial DNA as We Do Not Know It: mt-Genome Organization and Evolution in Nonbilaterian Lineages.Instability of the octarepeat region of the human prion protein gene.Similar patterns of clonally expanded somatic mtDNA mutations in the colon of heterozygous mtDNA mutator mice and ageing humansHigh-fat and obesogenic diets: current and future strategies to fight obesity and diabetes.Signaling the mitochondrial unfolded protein response.Mitochondrial DNA deletions are associated with non-B DNA conformationsHigh brain lactate is a hallmark of aging and caused by a shift in the lactate dehydrogenase A/B ratio
P2860
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P2860
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
gotara zanistî
@ku-latn
scientific article published on January 2010
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
name
Somatic mitochondrial DNA mutations in mammalian aging.
@en
Somatic mitochondrial DNA mutations in mammalian aging.
@nl
type
label
Somatic mitochondrial DNA mutations in mammalian aging.
@en
Somatic mitochondrial DNA mutations in mammalian aging.
@nl
prefLabel
Somatic mitochondrial DNA mutations in mammalian aging.
@en
Somatic mitochondrial DNA mutations in mammalian aging.
@nl
P1476
Somatic mitochondrial DNA mutations in mammalian aging.
@en
P2093
Nils-Göran Larsson
P304
P356
10.1146/ANNUREV-BIOCHEM-060408-093701
P577
2010-01-01T00:00:00Z