about
p73: a Positive or Negative Regulator of Angiogenesis, or Both?Modelling mutational landscapes of human cancers in vitro.Loss of Cdk2 and cyclin A2 impairs cell proliferation and tumorigenesisImmortalization of MEF is characterized by the deregulation of specific miRNAs with potential tumor suppressor activityEfficient introduction of specific TP53 mutations into mouse embryonic fibroblasts and embryonic stem cells.Pyruvate kinase isoform expression alters nucleotide synthesis to impact cell proliferationFibroblast sources: Where can we get them?Mice deficient in poly(C)-binding protein 4 are susceptible to spontaneous tumors through increased expression of ZFP871 that targets p53 for degradation.TP53 supports basal-like differentiation of mammary epithelial cells by preventing translocation of deltaNp63 into nucleoli.Controversial aspects of oncogene-induced senescence.The Intricate Interplay between Mechanisms Underlying Aging and Cancer.Freshly frozen E18 rat cortical cells can generate functional neural networks after standard cryopreservation and thawing proceduresModeling cancer driver events in vitro using barrier bypass-clonal expansion assays and massively parallel sequencing.Nutlin-3a selects for cells harbouring TP53 mutations.Impact of lysosomal storage disorders on biology of mesenchymal stem cells: Evidences from in vitro silencing of glucocerebrosidase (GBA) and alpha-galactosidase A (GLA) enzymes.SATB1 collaborates with loss of p16 in cellular transformation.Mammalian cells acquire epigenetic hallmarks of human cancer during immortalization.Carcinogen-specific mutational and epigenetic alterations in INK4A, INK4B and p53 tumour-suppressor genes drive induced senescence bypass in normal diploid mammalian cells.How to measure RNA expression in rare senescent cells expressing any specific protein such as p16Ink4a.Senescence in the aging process.ASCIZ/ATMIN is dispensable for ATM signaling in response to replication stress.Spontaneous inactivating p53 mutations and the "selfish cell".Runx3 plays a critical role in restriction-point and defense against cellular transformation.Mutation Analysis in Cultured Cells of Transgenic Rodents.Silencing of RB1 but not of RB2/P130 induces cellular senescence and impairs the differentiation potential of human mesenchymal stem cells.Cryopreservation of Primary Mouse Neurons: The Benefit of Neurostore Cryoprotective Medium.
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description
article científic
@ca
article scientifique
@fr
articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on 31 March 2010
@en
vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
How to become immortal: let MEFs count the ways
@en
How to become immortal: let MEFs count the ways.
@nl
type
label
How to become immortal: let MEFs count the ways
@en
How to become immortal: let MEFs count the ways.
@nl
prefLabel
How to become immortal: let MEFs count the ways
@en
How to become immortal: let MEFs count the ways.
@nl
P2093
P2860
P921
P356
P1433
P1476
How to become immortal: let MEFs count the ways
@en
P2093
Adam Odell
Jon Askham
Monica Hollstein
P2860
P304
P356
10.18632/AGING.100129
P577
2010-03-31T00:00:00Z