Translation initiation of ornithine decarboxylase and nucleocytoplasmic transport of cyclin D1 mRNA are increased in cells overexpressing eukaryotic initiation factor 4E.
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The signal sequence coding region promotes nuclear export of mRNAEukaryotic translation initiation factor 4E is a cellular target for toxicity and death due to exposure to cadmium chlorideNegative regulation of protein translation by mitogen-activated protein kinase-interacting kinases 1 and 2PML RING suppresses oncogenic transformation by reducing the affinity of eIF4E for mRNA.The proline-rich homeodomain protein, PRH, is a tissue-specific inhibitor of eIF4E-dependent cyclin D1 mRNA transport and growthTracking a refined eIF4E-binding motif reveals Angel1 as a new partner of eIF4EmTOR controls cell cycle progression through its cell growth effectors S6K1 and 4E-BP1/eukaryotic translation initiation factor 4ERegulation of cyclin D1 RNA stability by SNIP1Molecular dissection of the eukaryotic initiation factor 4E (eIF4E) export-competent RNPA new MIF4G domain-containing protein, CTIF, directs nuclear cap-binding protein CBP80/20-dependent translationA second look at cellular mRNA sequences said to function as internal ribosome entry sitesPhosphorylation of the cap-binding protein eukaryotic translation initiation factor 4E by protein kinase Mnk1 in vivoFunctional interaction between RAFT1/FRAP/mTOR and protein kinase cdelta in the regulation of cap-dependent initiation of translationNitric oxide-induced cytostasis and cell cycle arrest of a human breast cancer cell line (MDA-MB-231): potential role of cyclin D1A role for the eIF4E-binding protein 4E-T in P-body formation and mRNA decayExpression of constitutively active 4EBP-1 enhances p27Kip1 expression and inhibits proliferation of MCF7 breast cancer cellsSignalling to eIF4E in cancerA review of the association between osteosarcoma metastasis and protein translationTranslational control mechanisms in metabolic regulation: critical role of RNA binding proteins, microRNAs, and cytoplasmic RNA granulesStructural Insights into the Allosteric Effects of 4EBP1 on the Eukaryotic Translation Initiation Factor eIF4EeIF4E3 acts as a tumor suppressor by utilizing an atypical mode of methyl-7-guanosine cap recognitionPosttranscriptional control of gene expression in yeast.Target of rapamycin (TOR)-signaling and RAIP motifs play distinct roles in the mammalian TOR-dependent phosphorylation of initiation factor 4E-binding protein 1eIF4E promotes nuclear export of cyclin D1 mRNAs via an element in the 3'UTRCyclins: roles in mitogenic signaling and oncogenic transformationThe serine-threonine kinase MNK1 is post-translationally stabilized by PML-RARalpha and regulates differentiation of hematopoietic cellsEvidence that the Pim1 kinase gene is a direct target of HOXA9Protein kinase C alpha signaling inhibits cyclin D1 translation in intestinal epithelial cellsRibosome-mediated specificity in Hox mRNA translation and vertebrate tissue patterningIntestinal cell kinase, a MAP kinase-related kinase, regulates proliferation and G1 cell cycle progression of intestinal epithelial cells.Loss of the tumor suppressor gene NF2, encoding merlin, constitutively activates integrin-dependent mTORC1 signaling.Apoptosis resistance downstream of eIF4E: posttranscriptional activation of an anti-apoptotic transcript carrying a consensus hairpin structure.Asymmetrical beta-actin mRNA translation in growth cones mediates attractive turning to netrin-1.Cloning and characterization of human eIF4E genes.Multi-level gene expression profiles affected by thymidylate synthase and 5-fluorouracil in colon cancer.Pondering the promyelocytic leukemia protein (PML) puzzle: possible functions for PML nuclear bodies.An approach to analyse the specific impact of rapamycin on mRNA-ribosome association.Translation of a small subset of Caenorhabditis elegans mRNAs is dependent on a specific eukaryotic translation initiation factor 4E isoform.Ribavirin suppresses eIF4E-mediated oncogenic transformation by physical mimicry of the 7-methyl guanosine mRNA capThe PTEN/MMAC1 tumor suppressor phosphatase functions as a negative regulator of the phosphoinositide 3-kinase/Akt pathway.
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Translation initiation of ornithine decarboxylase and nucleocytoplasmic transport of cyclin D1 mRNA are increased in cells overexpressing eukaryotic initiation factor 4E.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on February 1996
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Translation initiation of orni ...... karyotic initiation factor 4E.
@en
Translation initiation of orni ...... karyotic initiation factor 4E.
@nl
type
label
Translation initiation of orni ...... karyotic initiation factor 4E.
@en
Translation initiation of orni ...... karyotic initiation factor 4E.
@nl
prefLabel
Translation initiation of orni ...... karyotic initiation factor 4E.
@en
Translation initiation of orni ...... karyotic initiation factor 4E.
@nl
P2093
P2860
P356
P1476
Translation initiation of orni ...... karyotic initiation factor 4E.
@en
P2093
P2860
P304
P356
10.1073/PNAS.93.3.1065
P407
P577
1996-02-01T00:00:00Z