Structural Insights into the Allosteric Effects of 4EBP1 on the Eukaryotic Translation Initiation Factor eIF4E - Wikidata - awgldk - TriplyDB

Structural Insights into the Allosteric Effects of 4EBP1 on the Eukaryotic Translation Initiation Factor eIF4E

Structural Insights into the Allosteric Effects of 4EBP1 on the Eukaryotic Translation Initiation Factor eIF4E

http://www.wikidata.org/entity/Q27676269

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Eukaryotic translation initiation is controlled by cooperativity effects within ternary complexes of 4E-BP1, eIF4E, and the mRNA 5' cap Crystal structure of a minimal eIF4E-Cup complex reveals a general mechanism of eIF4E regulation in translational repression Structural Basis of the Interaction of MbtH-like Proteins, Putative Regulators of Nonribosomal Peptide Biosynthesis, with Adenylating Enzymes Human Management of a Wild Plant Modulates the Evolutionary Dynamics of a Gene Determining Recessive Resistance to Virus Infection.HIV-1 Gag Blocks Selenite-Induced Stress Granule Assembly by Altering the mRNA Cap-Binding Complex.The Role of Dynamics and Allostery in the Inhibition of the eIF4E/eIF4G Translation Initiation Factor Complex Characterization of the Raptor/4E-BP1 interaction by chemical cross-linking coupled with mass spectrometry analysis.The eukaryotic translation initiation factor eIF4E in the nucleus: taking the road less traveled.Eukaryotic initiation factor 4E-binding protein 1 (4E-BP1): a master regulator of mRNA translation involved in tumorigenesis.Structure of eIF4E in Complex with an eIF4G Peptide Supports a Universal Bipartite Binding Mode for Protein Translation.A versatile assay for RNA-binding proteins in living cells.The molecular choreography of protein synthesis: translational control, regulation, and pathways.4E-BPs require non-canonical 4E-binding motifs and a lateral surface of eIF4E to repress translation.Impersonalized medicine.Structural basis for LeishIF4E-1 modulation by an interacting protein in the human parasite Leishmania major.The Role of Dynamics and Allostery in the Inhibition of the eIF4E/eIF4G Translation Initiation Factor Complex

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P2860

Structural Insights into the Allosteric Effects of 4EBP1 on the Eukaryotic Translation Initiation Factor eIF4E

http://www.wikidata.org/entity/Q27676269

description

2012 nî lūn-bûn

@nan

2012 թուականի Փետրուարին հրատարակուած գիտական յօդուած

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2012 թվականի փետրվարին հրատարակված գիտական հոդված

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2012年の論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年论文

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Structural Insights into the A ...... lation Initiation Factor eIF4E

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Structural Insights into the A ...... lation Initiation Factor eIF4E

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Structural Insights into the A ...... lation Initiation Factor eIF4E

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Structural Insights into the A ...... lation Initiation Factor eIF4E

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J.JMB.2011.12.002

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Journal of Molecular Biology

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Structural Insights into the A ...... lation Initiation Factor eIF4E

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Amy K Wernimont

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Hee-Won Park

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Katherine L B Borden

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Laurent Volpon

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Lucy Nedyalkova

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Michael J Osborne

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Nadeem Siddiqui

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P2860

Regulation of human eIF4E by 4E-BP1: binding analysis using surface plasmon resonance

PML RING suppresses oncogenic transformation by reducing the affinity of eIF4E for mRNA.

Structural basis for mRNA Cap-Binding regulation of eukaryotic initiation factor 4E by 4E-binding protein, studied by spectroscopic, X-ray crystal structural, and molecular dynamics simulation methods

The translation initiation factor eIF-4E binds to a common motif shared by the translation factor eIF-4 gamma and the translational repressors 4E-binding proteins

The Protein Data Bank

Cap-dependent translation initiation in eukaryotes is regulated by a molecular mimic of eIF4G

Crystal structures of 7-methylguanosine 5'-triphosphate (m(7)GTP)- and P(1)-7-methylguanosine-P(3)-adenosine-5',5'-triphosphate (m(7)GpppA)-bound human full-length eukaryotic initiation factor 4E: biological importance of the C-terminal flexible reg

Biophysical studies of eIF4E cap-binding protein: recognition of mRNA 5' cap structure and synthetic fragments of eIF4G and 4E-BP1 proteins

Ribosome loading onto the mRNA cap is driven by conformational coupling between eIF4G and eIF4E

Crystallographic and mass spectrometric characterisation of eIF4E with N7-alkylated cap derivatives

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10.1016/J.JMB.2011.12.002

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