P-glycoprotein confers methotrexate resistance in 3T6 cells with deficient carrier-mediated methotrexate uptake.
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Exploiting nanotechnology to overcome tumor drug resistance: Challenges and opportunitiesMDR1 and ERCC1 expression predict outcome of patients with locally advanced bladder cancer receiving adjuvant chemotherapy.Methylation-dependent silencing of the reduced folate carrier gene in inherently methotrexate-resistant human breast cancer cells.TLR signaling modulates side effects of anticancer therapy in the small intestine.Snapshots of ligand entry, malleable binding and induced helical movement in P-glycoprotein.Resistance to antifolates.P-glycoprotein function involves conformational transitions detectable by differential immunoreactivity.ABC multidrug transporters in schistosomes and other parasitic flatwormsMechanisms of antifolate resistance and methotrexate efficacy in leukemia cells.Mechanisms underlying methotrexate-induced pulmonary toxicity.Molecular mechanisms of cisplatin resistance in bladder cancer.In the Pursuit of Methotrexate Treatment Response Biomarker in Juvenile Idiopathic Arthritis-Are We Getting Closer to Personalised Medicine?Overexpression of P-glycoprotein induces acquired resistance to imatinib in chronic myelogenous leukemia cells.Mrp2 is involved in the efflux and disposition of fosinopril.Up-regulation of P-glycoprotein confers acquired resistance to 6-mercaptopurine in human chronic myeloid leukemia cells.P-glycoprotein limits oral availability, brain penetration, and toxicity of an anionic drug, the antibiotic salinomycin.The use of Tris-lipidation to modify drug cytotoxicity in multidrug resistant cells expressing P-glycoprotein or MRP1.Effect of cyclosporin on distribution of methotrexate into the brain of rats.MDR gene expression analysis of six drug-resistant ovarian cancer cell lines.CAN a P-gp modulator assist in the control of methotrexate concentrations in the rat brain? -inhibitory effects of rhodamine 123, a specific substrate for P-gp, on methotrexate excretion from the rat brain and its optimal route of administration.Characterizing the binding interactions between P-glycoprotein and eight known cardiovascular transport substrates.Effect of varying types of anti-arthritic drugs on Th1 and Th2 immune responses in mice.Involvement of P-glycoprotein in the release of cytokines from peripheral blood mononuclear cells treated with methotrexate and dexamethasone.Prognostic value of P-glycoprotein and leukocyte differentiation antigens in chronic myeloid leukemia.Genetic determinants for chemo- and radiotherapy resistance in bladder cancer.Investigation of the Importance of Multidrug Resistance-Associated Protein 4 (Mrp4/Abcc4) in the Active Efflux of Anionic Drugs Across the Blood-Brain Barrier.
P2860
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P2860
P-glycoprotein confers methotrexate resistance in 3T6 cells with deficient carrier-mediated methotrexate uptake.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on February 1996
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
P-glycoprotein confers methotr ...... -mediated methotrexate uptake.
@en
P-glycoprotein confers methotr ...... -mediated methotrexate uptake.
@nl
type
label
P-glycoprotein confers methotr ...... -mediated methotrexate uptake.
@en
P-glycoprotein confers methotr ...... -mediated methotrexate uptake.
@nl
prefLabel
P-glycoprotein confers methotr ...... -mediated methotrexate uptake.
@en
P-glycoprotein confers methotr ...... -mediated methotrexate uptake.
@nl
P2093
P2860
P356
P1476
P-glycoprotein confers methotr ...... -mediated methotrexate uptake.
@en
P2093
D de Graaf
E B Mechetner
I B Roninson
R C Sharma
R T Schimke
P2860
P304
P356
10.1073/PNAS.93.3.1238
P407
P577
1996-02-01T00:00:00Z